Vitamin B12/ja: Difference between revisions

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==定義==

==Definition==

~~Vitamin B~~<sub>12</sub> ~~is a~~ [[~~coordination complex~~]] of [[~~cobalt~~]]~~, which occupies the center of a~~ [[corrin]] ~~ligand and is further bound to a~~ [[benzimidazole]] ligand and adenosyl group. A number of related species are known and these behave similarly, in particular all function as vitamins. This collection of compounds is sometimes referred to as "cobalamins". These chemical compounds have a similar molecular structure, each of which shows vitamin activity in a vitamin-deficient biological system, they are referred to as [[vitamer]]~~s. The vitamin activity is as a~~ [[coenzyme~~]], meaning that its presence is required for some enzyme-catalyzed reactions.~~

ビタミンB<sub>12</sub>は[[cobalt/ja|コバルト]]の[[coordination complex/ja|配位錯体]]で、[[corrin/ja|コリン]]配位子の中心を占め、さらに[[benzimidazole/ja|ベンズイミダゾール]]配位子とアデノシル基が結合している。多くの近縁種が知られており、これらは同様の挙動を示し、特にすべてがビタミンとして機能する。この化合物群は「コバラミン」と呼ばれることもある。これらの化合物は類似した分子構造を持ち、それぞれがビタミン欠乏の生体系でビタミン活性を示すことから、[[vitamer/ja|ビタマー]]と呼ばれる。ビタミンの活性は[[coenzyme/ja|補酵素]]としてのもので、酵素触媒反応にその存在が必要であることを意味する。

* [[adenosylcobalamin]]

* [[cyanocobalamin]], the adenosyl ligand in vitamin B<sub>12</~~sub> is replaced by [[cyanide~~]].

* [[hydroxocobalamin]], the adenosyl ligand in vitamin B<sub>12</sub> is replaced by [[hydroxide]].

* [[methylcobalamin]], the adenosyl ligand in vitamin B<sub>12</sub> is replaced by [[methyl]].

~~</div>~~

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 {{TOC limit}}
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+==定義==
-==Definition==
+{{Anchor|Definition}}
-Vitamin B<sub>12</sub> is a [[coordination complex]] of [[cobalt]], which occupies the center of a [[corrin]] ligand and is further bound to a [[benzimidazole]] ligand and adenosyl group. A number of related species are known and these behave similarly, in particular all function as vitamins. This collection of compounds is sometimes referred to as "cobalamins". These chemical compounds have a similar molecular structure, each of which shows vitamin activity in a vitamin-deficient biological system, they are referred to as [[vitamer]]s. The vitamin activity is as a [[coenzyme]], meaning that its presence is required for some enzyme-catalyzed reactions.
+ビタミンB<sub>12</sub>は[[cobalt/ja|コバルト]]の[[coordination complex/ja|配位錯体]]で、[[corrin/ja|コリン]]配位子の中心を占め、さらに[[benzimidazole/ja|ベンズイミダゾール]]配位子とアデノシル基が結合している。多くの近縁種が知られており、これらは同様の挙動を示し、特にすべてがビタミンとして機能する。この化合物群は「コバラミン」と呼ばれることもある。これらの化合物は類似した分子構造を持ち、それぞれがビタミン欠乏の生体系でビタミン活性を示すことから、[[vitamer/ja|ビタマー]]と呼ばれる。ビタミンの活性は[[coenzyme/ja|補酵素]]としてのもので、酵素触媒反応にその存在が必要であることを意味する。
-* [[adenosylcobalamin]]
-* [[cyanocobalamin]], the adenosyl ligand in vitamin B<sub>12</sub> is replaced by [[cyanide]].
-* [[hydroxocobalamin]], the adenosyl ligand in vitamin B<sub>12</sub> is replaced by [[hydroxide]].
-* [[methylcobalamin]], the adenosyl ligand in vitamin B<sub>12</sub> is replaced by [[methyl]].
-</div>
 <div lang="en" dir="ltr" class="mw-content-ltr">