Xanthine oxidase inhibitor: Difference between revisions

Line 3:

{{Short description|Substance that decreases activity of xanthine oxidase, an enzyme involved in purine metabolism}}

{| class="wikitable sortable" style="width:100%"

|+XO阻害剤

|-

!一般名

!先発名

!class="unsortable"| 日本

!創薬/開発

!備考

|-

|[[allopurinol/ja]]

|[https://gskpro.com/ja-jp/products-info/zyloric/index/ ザイロリック](Zyloric)

([https://pins.japic.or.jp/pdf/newPINS/00048894.pdf PI]) ([https://gskpro.com/content/dam/global/hcpportal/ja_JP/products-info/zyloric/zyloric_tab-if.pdf IF])

|販売

|[[GSK plc]]

|

|-

|[[febuxostat/ja]]

|[https://medical.teijin-pharma.co.jp/product/iyaku/fe_fet.html フェブリク](Febric) ([https://pins.japic.or.jp/pdf/newPINS/00059341.pdf PI]) ([https://medical.teijin-pharma.co.jp/content/dam/teijin-medical-web/sites/documents/product/iyaku/fe_fet/fe_fet_if_2211.pdf IF])

|販売

|[[帝人ファーマ]]

|

|-

|[[topiroxostat/ja]]

|[https://med.skk-net.com/supplies/uriadec/ ウリアデック](Uriadec)

([https://med.skk-net.com/supplies/products/item/UDC2205.pdf PI]) ([https://med.skk-net.com/supplies/products/item/UDC_if_2211.pdf IF])

|販売

|[[三和化学研究所]]

|-

|}

A '''xanthine oxidase inhibitor''' is any substance that [[Enzyme inhibitor|inhibits]] the activity of [[xanthine oxidase]], an [[enzyme]] involved in [[purine metabolism]]. In [[human]]s, inhibition of xanthine oxidase reduces the production of [[uric acid]], and several [[medication]]s that inhibit xanthine oxidase are [[Indication (medicine)|indicated]] for treatment of [[hyperuricemia]] and related medical conditions including [[gout]]. Xanthine oxidase inhibitors are being investigated for management of [[reperfusion injury]].

@@ Line 3: / Line 3: @@
 <!--T:1-->
 {{Short description|Substance that decreases activity of xanthine oxidase, an enzyme involved in purine metabolism}}
+{{Drug List/ja}}
+{| class="wikitable sortable" style="width:100%"
+|+XO阻害剤
+|-
+!一般名
+!先発名
+!class="unsortable"| 日本
+!創薬/開発
+!備考
+|-
+|[[allopurinol/ja]]
+|[https://gskpro.com/ja-jp/products-info/zyloric/index/ ザイロリック](Zyloric)
+([https://pins.japic.or.jp/pdf/newPINS/00048894.pdf PI]) ([https://gskpro.com/content/dam/global/hcpportal/ja_JP/products-info/zyloric/zyloric_tab-if.pdf IF])
+|販売
+|[[GSK plc]]
+|
+|-
+|[[febuxostat/ja]]
+|[https://medical.teijin-pharma.co.jp/product/iyaku/fe_fet.html フェブリク](Febric) ([https://pins.japic.or.jp/pdf/newPINS/00059341.pdf PI]) ([https://medical.teijin-pharma.co.jp/content/dam/teijin-medical-web/sites/documents/product/iyaku/fe_fet/fe_fet_if_2211.pdf IF])
+|販売
+|[[帝人ファーマ]]
+|
+|-
+|[[topiroxostat/ja]]
+|[https://med.skk-net.com/supplies/uriadec/ ウリアデック](Uriadec)
+([https://med.skk-net.com/supplies/products/item/UDC2205.pdf PI]) ([https://med.skk-net.com/supplies/products/item/UDC_if_2211.pdf IF])
+|販売
+|[[三和化学研究所]]
+|-
+|}
 A '''xanthine oxidase inhibitor''' is any substance that [[Enzyme inhibitor|inhibits]] the activity of [[xanthine oxidase]], an [[enzyme]] involved in [[purine metabolism]].  In [[human]]s, inhibition of xanthine oxidase reduces the production of [[uric acid]], and several [[medication]]s that inhibit xanthine oxidase are [[Indication (medicine)|indicated]] for treatment of [[hyperuricemia]] and related medical conditions including [[gout]]. Xanthine oxidase inhibitors are being investigated for management of [[reperfusion injury]].