Xanthine oxidase inhibitor/en: Difference between revisions
Xanthine oxidase inhibitor/en
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{{Short description|Substance that decreases activity of xanthine oxidase, an enzyme involved in purine metabolism}} | {{Short description|Substance that decreases activity of xanthine oxidase, an enzyme involved in purine metabolism}} | ||
{{Drug List/ja}} | |||
{| class="wikitable sortable" style="width:100%" | |||
|+XO阻害剤 | |||
|- | |||
!一般名 | |||
!先発名 | |||
!class="unsortable"| 日本 | |||
!創薬/開発 | |||
!備考 | |||
|- | |||
|[[allopurinol/ja]] | |||
|[https://gskpro.com/ja-jp/products-info/zyloric/index/ ザイロリック](Zyloric) | |||
([https://pins.japic.or.jp/pdf/newPINS/00048894.pdf PI]) ([https://gskpro.com/content/dam/global/hcpportal/ja_JP/products-info/zyloric/zyloric_tab-if.pdf IF]) | |||
|販売 | |||
|[[GSK plc]] | |||
| | |||
|- | |||
|[[febuxostat/ja]] | |||
|[https://medical.teijin-pharma.co.jp/product/iyaku/fe_fet.html フェブリク](Febric) ([https://pins.japic.or.jp/pdf/newPINS/00059341.pdf PI]) ([https://medical.teijin-pharma.co.jp/content/dam/teijin-medical-web/sites/documents/product/iyaku/fe_fet/fe_fet_if_2211.pdf IF]) | |||
|販売 | |||
|[[帝人ファーマ]] | |||
| | |||
|- | |||
|[[topiroxostat/ja]] | |||
|[https://med.skk-net.com/supplies/uriadec/ ウリアデック](Uriadec) | |||
([https://med.skk-net.com/supplies/products/item/UDC2205.pdf PI]) ([https://med.skk-net.com/supplies/products/item/UDC_if_2211.pdf IF]) | |||
|販売 | |||
|[[三和化学研究所]] | |||
| | |||
|- | |||
|} | |||
A '''xanthine oxidase inhibitor''' is any substance that [[Enzyme inhibitor|inhibits]] the activity of [[xanthine oxidase]], an [[enzyme]] involved in [[purine metabolism]]. In [[human]]s, inhibition of xanthine oxidase reduces the production of [[uric acid]], and several [[medication]]s that inhibit xanthine oxidase are [[Indication (medicine)|indicated]] for treatment of [[hyperuricemia]] and related medical conditions including [[gout]]. Xanthine oxidase inhibitors are being investigated for management of [[reperfusion injury]]. | A '''xanthine oxidase inhibitor''' is any substance that [[Enzyme inhibitor|inhibits]] the activity of [[xanthine oxidase]], an [[enzyme]] involved in [[purine metabolism]]. In [[human]]s, inhibition of xanthine oxidase reduces the production of [[uric acid]], and several [[medication]]s that inhibit xanthine oxidase are [[Indication (medicine)|indicated]] for treatment of [[hyperuricemia]] and related medical conditions including [[gout]]. Xanthine oxidase inhibitors are being investigated for management of [[reperfusion injury]]. | ||