Main public logs
Jump to navigation
Jump to search
Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 10:01, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/21/ja (Created page with "歴史的に、生理学的形態は当初シアノコバラミンであると考えられていた。これは、細菌によって生産されたヒドロキソコバラミンが細菌培養物から分離した後、活性炭カラムで精製中にシアノコバラミンに変化したためである（シアン化物は活性炭に天然に存在するため）。シアノコバラミンがほとん...")
- 10:01, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/20/ja (Created page with "==生産== {{Anchor|Production}} シアノコバラミンは細菌発酵によって商業的に調製される。様々な微生物による発酵により、メチルコバラミン、ヒドロキソコバラミン、アデノシルコバラミンの混合物が得られる。これらの化合物は亜硝酸ナトリウムと...")
- 09:59, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/19/ja (Created page with "この方法で調製されるコバラミン類似体には、天然に存在する補酵素メチルコバラミンやコバミドのほか、ビニルコバラミン、カルボキシメチルコバラミン、シクロヘキシルコバラミンなど、天然には存在しないコバラミンも含まれる。この反応は、化学的脱ハロゲン化、有機試薬、光増感触媒系の...")
- 09:58, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/18/ja (Created page with "例えば、シアノコバラミンは、{{chem|B|12s}}への還元を経て、対応するハロゲン化アルキル、ハロゲン化アシル、アルケンまたはアルキンの付加によって、その類似体であるコバラミンに変換することができる。立体障害は{{chem|B|12}}補酵素アナログの合成における主要な制限因子である...")
- 09:55, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/17/ja (Created page with "{{chem|B|12s}}は水溶液中で知られている最も求核性の高い種の一つである。この性質により、ハロゲン化アルキルやハロゲン化ビニルに対する求核攻撃によって、異なる置換基を持つコバラミン類似体を簡便に調製することができる。")
- 09:55, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/16/ja (Created page with "{{chem|B|12r}}と{{chem|B|12s}}はシアノコバラミンから電位制御還元、またはアルカリ溶液中の水素化ホウ素ナトリウム、酢酸中の亜鉛を用いた化学還元、またはチオールの作用によって調製することができる。{{chem|B|12r}}も{{chem|B|12s}}も酸素のない条件下では無期限に安定である。{{chem|B|12r}}は溶液中では橙...")
- 09:54, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/15/ja (Created page with "===化学反応=== thumb|Co(I)(上)、Co(II)(中)、Co(III)(下)の還元型シアノコバラミン コバラミンでは、コバルトは通常3価のCo(III)の状態で存在する。しかし、還元条件下では、コバルト中心はCo(II)、あるいはCo(I)に還元され、通常、それぞれ還元型、超還元型を表す{{chem|B|12r}}、{{chem|B|12s}}と表記される。")
- 09:53, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/14/ja (Created page with "シアノコバラミンはビタミン{{chem|B|12}}ファミリー（体内に入れると{{chem|B|12}}として機能する化学物質のファミリー）の中で最も広く製造されているビタマーの一つであり、その理由はシアノコバラミンが{{chem|B|12}}の中で最も空気中で安定だからである。細菌発酵によって生成された後、精製するのが最も簡単である。...")
- 09:51, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/13/ja (Created page with "==化学== {{Anchor|Chemistry}} ビタミン{{chem|B|12}}は、ビタミン{{chem|B|12}}のあらゆるビタマーの「総称記述子」名である。ヒトを含む動物はシアノコバラミンを活性型ビタミン{{chem|B|12}}化合物のいずれかに変換することができる。")
- 09:50, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/12/ja (Created page with "ビタミン{{chem|B|12}}欠乏を同時に伴う巨赤芽球性貧血の治療に{{chem|B|12}}ビタミン（シアノコバラミンも含む）を用いると、貧血解消時に赤血球産生の亢進とそれに伴うカリウムの細胞内取り込みにより低カリウム血症になる可能性がある。シアノコバラミンで治療した場合、Leber's disease/ja|...")
- 09:49, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/11/ja (Created page with "==副作用== {{Anchor|Side effects}} シアノコバラミン注射の起こりうる副作用には、じんましん、呼吸困難などのアレルギー反応、顔の発赤、腕、手、足、足首または下肢の腫れ、極度の口渇、および下痢が含まれる。重篤でない副作用には、頭痛、めまい、下肢痛、かゆみ、または発疹がある。")
- 09:48, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/10/ja (Created page with "シアノコバラミンもまた、ヒドロキシコバラミンを青酸中毒の治療に静脈内投与した後に体内で生成される（そして尿を介して排泄される）。")
- 09:48, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/9/ja (Created page with "==医療用途== {{Anchor|Medical use}} シアノコバラミンは通常、胃または腸の一部または全部を外科的に切除した後に処方され、ビタミン{{chem|B|12}}の十分な血清レベルを確保する。また、悪性貧血、ビタミン{{chem|B|12}}欠乏症（食物からの摂取量が少ないか、遺伝的またはその他の要因で吸収でき...")
- 09:46, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/30/ja (Created page with "=== 吸収と輸送 === ビタミン{{chem|B|12}}の不十分な吸収はセリアック病と関係があるかもしれない。ビタミン{{chem|B|12}}の腸管吸収には3つの異なるタンパク質分子が必要である： ハプトコリン、内在因子、トランスコバラミンIIである。")
- 09:45, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/8/ja (Created page with "<!-- Society and culture --> シアノコバラミンが最初に製造されたのは1940年代である。ジェネリック医薬品や市販薬として入手可能である。2021年には、5{{nbsp}}万件以上の処方で、米国で110番目によく処方される医薬品であった。")
- 09:44, 7 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/7/ja (Created page with "<!-- Side effects and mechanism --> シアノコバラミンは一般に忍容性が高い。軽度の副作用には、下痢、吐き気、胃のむかつき、かゆみなどがある。重篤な副作用には、アナフィラキシー、心不全を引き起こす低血中カリウムなどがある。コバルトアレルギーのある人やレーバー病の...")
- 22:13, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/31/ja (Created page with "== こちらも参照 == * メチルコバラミン * ヒドロキソコバラミン * アデノシルコバラミン * Cobalamin biosynthesis/ja")
- 22:13, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/32/ja (Created page with "{{-}}")
- 22:13, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/33/ja (Created page with "{{ATC navboxes/ja|A11|B03}} {{Tetrapyrroles/ja}} {{Dietary supplement/ja}} {{Portal bar | Medicine}}")
- 22:13, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/34/ja (Created page with "Category:B vitamins Category:Organocobalt compounds Category:Cofactors Category:Vitamin B12 Category:Corrinoids Category:Wikipedia medicine articles ready to translate")
- 22:12, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/6/ja (Created page with "<!-- Chemical and physical data --> | IUPAC_name = | C=63 | H=88 | Co=1 | N=14 | O=14 | P=1 | SMILES = CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3] | StdInChI = 1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19...")
- 22:11, 6 April 2024 Fire talk contribs created page Cyanocobalamin/ja (Created page with "<!-- Legal status --> | legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> | legal_AU_comment = | legal_BR = <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F--> | legal_BR_comment = | legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_CA_comment = | legal_DE = <!-- Anlage I, II, III or Unscheduled--> | legal_DE_comment = | legal_NZ = <!-- Class A, B, C --> | legal_NZ_comment = | legal_UK = <!-- GSL, P, POM...")
- 22:10, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/5/ja (Created page with "<!-- Identifiers --> | CAS_number = 68-19-9 | CAS_supplemental = | PubChem = 16212801 | PubChemSubstance = | IUPHAR_ligand = | DrugBank = DB00115 | ChemSpiderID = 24921423 | UNII = P6YC3EG204 | KEGG = D00166 | ChEBI = | ChEMBL = 2110563 | NIAID_ChemDB = | PDB_ligand = | synonyms =")
- 22:10, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/4/ja (Created page with "<!-- Pharmacokinetic data --> | bioavailability = | protein_bound = | metabolism = | metabolites = | onset = | elimination_half-life = | duration_of_action = | excretion =")
- 22:10, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/3/ja (Created page with "<!-- Legal status --> | legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> | legal_AU_comment = | legal_BR = <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F--> | legal_BR_comment = | legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_CA_comment = | legal_DE = <!-- Anlage I, II, III or Unscheduled--> | legal_DE_comment = | legal_NZ = <!-- Class A, B, C --> | legal_NZ_comment = | legal_UK = <!-- GSL, P, POM...")
- 22:10, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/2/ja (Created page with "<!-- Clinical data --> | pronounce = sye AN oh koe BAL a min | tradename = Cobolin-M, Depo-Cobolin, others | Drugs.com = {{drugs.com|ppa|cyanocobalamin}} | MedlinePlus = a604029 | DailyMedID = Cyanocobalamin | pregnancy_AU= | pregnancy_AU_comment = Exempt | pregnancy_category= | routes_of_administration = By mouth/ja, intramuscular/ja, nasal spray/ja | class = | ATCvet = | ATC_prefix = B03...")
- 22:10, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/1/ja (Created page with "{{Infobox drug | image = Cyanocobalamin-b12.png | width = | alt = | caption = 骨格式 | image2 = Cyanocobalamin-from-xtal-3D-st-noH.png | width2 = | alt2 = | caption2 = 結晶構造に基づくシアノコバラミンのスティックモデル")
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Cyanocobalamin/en (Updating to match new version of source page) Tags: Mobile edit Mobile web edit
- 22:09, 6 April 2024 Fire talk contribs created page Translations:Cyanocobalamin/Page display title/ja (Created page with "シアノコバラミン")
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/34/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/33/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/32/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/31/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/30/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/29/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/28/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/27/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/26/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/25/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/24/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/23/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/22/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/21/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/20/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/19/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/18/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/17/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/16/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/15/en (Importing a new version from external source)
- 22:09, 6 April 2024 FuzzyBot talk contribs created page Translations:Cyanocobalamin/14/en (Importing a new version from external source)
