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15:51, 5 February 2024 Fire talk contribs created page water-soluble vitamin biosynthetic process (Q20490) (wbeditentity-create:2|en: water-soluble vitamin biosynthetic process, The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water.)
15:50, 5 February 2024 Fire talk contribs created page biotin biosynthetic process (Q20489) (wbeditentity-create:2|en: biotin biosynthetic process, The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.)
12:03, 5 February 2024 Fire talk contribs created page biotin metabolic process (Q20488) (wbeditentity-create:2|en: biotin metabolic process, the chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions)
11:59, 5 February 2024 Fire talk contribs created page Template:Diabetes/ja (Created page with "{{Navbox | name = Diabetes/ja | title = 糖尿病 | state = {{{state<includeonly>|autocollapse</includeonly>}}} | basestyle = background-color:turquoise | listclass = hlist | group1 = 型 | list1 = * 1型 * 2型 * LADA * Gestational diabetes/ja ** Diabetes and pregnancy/ja * Prediabetes/ja ** Impaired fasting glucose/ja ** Impaired glucose tolerance/j...")
11:51, 5 February 2024 Fire talk contribs created page Template:Oral hypoglycemics/ja (Created page with "{{Navbox with collapsible groups | name = Oral hypoglycemics and insulin analogs/ja | title = 経口糖尿病治療薬、インスリン製剤およびインスリンアナログ製剤、糖尿病に用いられるその他の薬剤（A10） | state = {{{state<includeonly>|expanded</includeonly>}}} | listclass = hlist | group1 = インスリン/insulin analog/ja|イ...")
11:32, 5 February 2024 Fire talk contribs created page Category:Sundown (Created page with "{{ビタミン}} Category:Dietary supplement Brand")
11:31, 5 February 2024 Fire talk contribs created page Sundown, Inc (Created page with "{{Infobox company | name = Sundown, Inc. | logo = | caption = | image = | image_caption = | trading_name = | native_name = | native_name_lang = | romanized_name = | former_name = | type = | traded_as = | ISIN = | industry = | genre = | fate = | predecessor = | successor = | foundation...")
11:28, 5 February 2024 Fire talk contribs created page Sundown Naturals (Redirected page to Sundown, Inc) Tag: New redirect
11:25, 5 February 2024 Fire talk contribs created page Vitamin B (Redirected page to B Vitamins) Tag: New redirect
11:24, 5 February 2024 Fire talk contribs created page Vitamin B/ja (Redirected page to ビタミンB群) Tag: New redirect
11:24, 5 February 2024 Fire talk contribs created page Vitamin B9/ja (Redirected page to 葉酸) Tag: New redirect
11:13, 5 February 2024 Fire talk contribs created page File:SundownNaturals B-Complex.jpg (Sundown Naturals B Complex)
11:13, 5 February 2024 Fire talk contribs uploaded File:SundownNaturals B-Complex.jpg (Sundown Naturals B Complex)
10:49, 5 February 2024 Fire talk contribs created page Translations:Diabetes medication/21/ja (Created page with "複数の後方視的研究の結果、ロシグリタゾンの安全性が懸念されているが、グループ全体としては糖尿病に有益な効果をもたらすことが確立されている。最も懸念されるのは、服用患者における重篤な心イベントの増加である。 ADOPT試験では、このタイプの薬剤による初期治療が病気の進行を防ぐ可能性があることが示された、糖尿病管理の臨床診療...")
10:48, 5 February 2024 Fire talk contribs created page Translations:Diabetes medication/59/ja (Created page with "{{DEFAULTSORT:Anti-Diabetic Drug}} Category:Anti-diabetic drugs")
10:48, 5 February 2024 Fire talk contribs created page Translations:Diabetes medication/58/ja (Created page with "{{Oral hypoglycemics/ja}} {{Major Drug Groups/ja}} {{Diabetes/ja}}")
10:48, 5 February 2024 Fire talk contribs created page Translations:Diabetes medication/57/ja (Created page with "== さらに読む == * {{cite book |author=Lebovitz, Harold E. |title=Therapy For Diabetes Mellitus and Related Disorders |publisher=American Diabetes Association |location=Alexandria, VA |year=2004 |edition=4th |isbn=978-1-58040-187-6 |url-access=registration |url=https://archive.org/details/therapyfordiabet0000unse_w1x1 }} * {{cite book |author1=Adams, Michael Ian |author2=Holland, Norman Norwood |title=Core Concepts in Pharmacology |url=https://archive.org/detail...")
10:48, 5 February 2024 Fire talk contribs created page Translations:Diabetes medication/56/ja (Created page with "== 代替医療 == {{Anchor|Alternative Medicine}} アーユルヴェーダ治療の効果は研究されているが、関連する研究や調査の方法論的欠陥のために、これらの治療の有効性に関する結論を出すことはできず、推奨するには証拠が不十分である。")
22:33, 4 February 2024 Fire talk contribs created page biotin binding (Q20487) (wbeditentity-create:2|en: biotin binding, Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation)
22:32, 4 February 2024 Fire talk contribs created page biotinate (Q20486) (wbeditentity-create:2|en: biotinate, chemical compound)
22:31, 4 February 2024 Fire talk contribs created page response to biotin (Q20485) (wbeditentity-create:2|en: response to biotin, Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.)
22:24, 4 February 2024 Fire talk contribs created page biotin (Q20484) (wbeditentity-create:2|en: biotin, chemical compound)
22:23, 4 February 2024 Fire talk contribs created page vitamin B (Q20483) (wbeditentity-create:2|en: vitamin B, group of vitamins)
22:21, 4 February 2024 Fire talk contribs created page B vitamins (Created page with "{{サプリメント}} {{Pathnav|Dietary supplement|frame=1}} {{Short description|Group of vitamins}} {{TOC_Right}} '''B vitamins''' are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. They are a chemically diverse class of compounds, but are associated in diet, often occurring together in the same foods. Dietary supplements containing all eight ar...")
20:59, 4 February 2024 Fire talk contribs created page Translations:Diabetes medication/55/ja (Created page with "==ジェネリック医薬品== {{Anchor|Generic}} 多くの抗糖尿病薬がジェネリック医薬品として入手可能である。これらには以下が含まれる： * スルホニル尿素薬-グリメピリド、グリピジド、グリブリド * ビグアナイド薬-メトホルミン * チアゾリジン系薬剤（Tzd）-ピオグリタゾン、アクトスジェネリック * Alpha-g...")
20:56, 4 February 2024 Fire talk contribs created page Category:Healthy Origins (Created page with "{{ビタミン}} Category:Dietary supplement Brand")
20:56, 4 February 2024 Fire talk contribs created page Healthy Origins (Created page with "{{Infobox company | name = Healthy Origins | logo = | caption = | image = | image_caption = | trading_name = | native_name = | native_name_lang = | romanized_name = | former_name = | type = | traded_as = | ISIN = | industry = | genre = | fate = | predecessor = | successor = | foundation...")
20:28, 4 February 2024 Fire talk contribs created page Template:ビタミン (Created page with "{| class="wikitable mw-collapsible mw-collapsed" |+ class="nowrap" | (EDIT) <big>ビタミン製品一覧</big> ! 種類 !! メーカ !! 写真 !! 製品名 !! 成分 !! 備考 |- |ビタミン D || Healthy Origins || 100px|| [https://healthyorigins.com/collections/healthy-origins-products?filter.v.price.gte=&filter.v.price.lte=&filter.p.product_type=Vitamin+...")
20:25, 4 February 2024 Fire talk contribs created page File:HealthyOrigins VitaminD3.jpg (Healthy Origins Vitamin D3 2000IU)
20:25, 4 February 2024 Fire talk contribs uploaded File:HealthyOrigins VitaminD3.jpg (Healthy Origins Vitamin D3 2000IU)
20:15, 4 February 2024 Fire talk contribs marked Calcium supplement for translation
20:13, 4 February 2024 Fire talk contribs marked Mineral (nutrient) for translation
20:10, 4 February 2024 Fire talk contribs marked Vitamin for translation
20:03, 4 February 2024 Fire talk contribs marked Vitamin D for translation
20:02, 4 February 2024 Fire talk contribs created page Translations:Vitamin/71/ja (Created page with "{{横線}}")
20:01, 4 February 2024 FuzzyBot talk contribs created page Translations:Vitamin/71/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
20:01, 4 February 2024 Fire talk contribs marked Vitamin for translation
19:43, 4 February 2024 Fire talk contribs created page Template:Vitamin D receptor modulators/ja (Created page with "{{Navbox | name = Vitamin D receptor modulators/ja | title = [ビタミンD受容体モジュレーター | bodyclass = hlist | state = {{{state<includeonly>|collapsed</includeonly>}}} | groupstyle = text-align:center; | group1 = {{abbrlink|VDR|Vitamin D receptor}} | list1 = * ''作動薬:'' 7-デヒドロコレステロール * 22-Oxacalcitriol/ja * 25-Hydroxyergocalciferol/ja * アルファカルシドール * Calcife...")
19:37, 4 February 2024 Fire talk contribs created page Translations:Diabetes medication/54/ja (Created page with "|- | メトホルミン | 肝臓に作用して糖新生を抑制し、AMPKシグナルを増加させることでインスリン抵抗性を低下させる。 | * 体重減少を伴う * 他の抗糖尿病薬と比較して低血糖のリスクが低い。 * 低密度リポ蛋白を減少させる。 * トリグリセリドを減少させる。 * 血圧には影響しない * 糖尿...")
19:28, 4 February 2024 Fire talk contribs created page Translations:Diabetes medication/53/ja (Created page with "{| class="wikitable sortable" |- ! colspan="5" style="background-color: #CCEEEE;" | 抗糖尿病薬の比較 |- ! ドラッグクラス ! 作用機序 ! 利点 ! 欠点 |- | スルホニル尿素 (glyburide/ja, glimepiride/ja, glipizide/ja) | KATPチャネルを阻害することで、膵臓β細胞からのインスリン分泌を刺激する。 | * 安価 * 作用発現が速い * blood pres...")
19:10, 4 February 2024 Fire talk contribs created page Translations:Diabetes medication/52/ja (Created page with "==比較== {{Anchor|Comparison}} 以下の表は、一般的な抗糖尿病薬をクラス分けして比較したものである。この表で「よりリスクが低い」、「より利便性が高い」などと比較している場合は、表の他の薬剤との比較である。")
19:10, 4 February 2024 Fire talk contribs created page Translations:Vitamin D/108/ja (Created page with "1969年、ビタミンD受容体と呼ばれるビタミンDに対する特異的結合タンパク質が同定された。その後間もなく、ビタミンDからカルシフェジオール、そして生物学的に活性な形態であるカルシトリオールへの変換が確認された。プレビタミンD3を介した皮膚におけるビタミンD3の光合成とそれに続く代謝が1980年に報告され...")
19:09, 4 February 2024 Fire talk contribs created page Translations:Vitamin D/107/ja (Created page with "1923年、ウィスコンシン大学のアメリカ人生化学者ハリー・スティーンボックは、紫外線を照射すると食品やその他の有機物のビタミンD含有量が増加することを実証した。ネズミの餌に紫外線を照射したところ、ネズミのくる病が治った。私財{{US$|300}}を投じて、スティーンボックは発明の特許を取得した。彼の...")
19:09, 4 February 2024 Fire talk contribs created page Translations:Vitamin D/106/ja (Created page with "1925年、7-デヒドロコレステロールに光を照射すると、脂溶性物質の一種（現在ではD3として知られている）が生成されることが確立された。アルフレッド・ファビアン・ヘスはこう述べている：「光はビタミンDに等しい。ドイツのゲッティンゲン大学の:en:Adolf Otto Reinhold Windaus|アドル...")
19:01, 4 February 2024 Fire talk contribs created page Translations:Vitamin D/105/ja (Created page with "== 歴史 == {{Anchor|History}} {{Further/ja|Vitamin/ja#History}} ビタミンDが発見されたのは1922年である。アメリカの研究者エルマー・マッコラムとマルグリット・デイヴィスは1914年にタラ肝油の中に後に"ビタミンA"と呼ばれる物質を発見した。イギリスの医師エドワード・メランビー...")
18:57, 4 February 2024 Fire talk contribs created page Translations:Diabetes medication/51/ja (Created page with "SGLT2阻害薬の副作用は、その作用機序に直接由来するものである；これらには以下のリスクの増加が含まれる：ケトアシドーシス、尿路感染症、カンジダ性外陰炎、低血糖症などである。")
18:56, 4 February 2024 Fire talk contribs created page Translations:Diabetes medication/50/ja (Created page with "例えば、以下のようなものがある： * ダパグリフロジン * カナグリフロジン * エンパグリフロジン * レモグリフロジン")
18:55, 4 February 2024 Fire talk contribs created page Translations:Diabetes medication/49/ja (Created page with "==SGLT2阻害剤== {{Anchor|SGLT2 inhibitors}} {{Main/ja|Gliflozin/ja}} SGLT2阻害薬は、腎臓のネフロンの腎尿細管に存在するナトリウム-グルコース結合トランスポーター2タンパク質をブロックし、グルコースの腎尿細管への再吸収、尿中へのグルコースの排泄を促進する。これにより、軽度の体重減少と、低血糖の危険性がほ...")
18:53, 4 February 2024 Fire talk contribs created page Translations:Vitamin D/104/ja (Created page with "カルシトリオールに対する細胞のいくつかの反応は、古典的なVDRE転写経路では速すぎるようで、ビタミンDの様々な''非ゲノム的''作用の発見につながった。膜に結合したPDIA3は、おそらくこの経路における代替受容体として機能しているのであろう。古典的なVDRはまだ役割を果たしているかもしれない。")
18:52, 4 February 2024 Fire talk contribs created page Translations:Vitamin D/103/ja (Created page with "=== 細胞内メカニズム === {{See also/ja|Vitamin D receptor/ja| Calcitriol/ja}} カルシトリオールは標的細胞に入り、細胞質内のビタミンD受容体に結合する。この活性化された受容体は核に入り、遺伝子上の特定のDNA配列であるビタミンD応答エレメント（VDRE）に結合する。これらの遺伝子の転写が刺激され、ビタミンDの作用を媒介するタンパ...")

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