Sulfonylurea/ja: Difference between revisions

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</gallery>

~~<div lang~~=~~"en" dir~~=~~"ltr" class~~=~~"mw-content-ltr">~~

===分類===

~~===Classification~~===

スルホニル尿素は、その抗糖尿病作用の治療効率に基づいて3つのクラスに分類される：

~~Sulfonylureas are divided into 3 classes on basis of therapeutic efficiency of their antidiabetic action:~~

* 第一世代の薬剤：

* ~~First-generation drugs:~~

~~They include~~ [[acetohexamide]], [[carbutamide]], [[chlorpropamide]], [[glycyclamide]] ~~(tolcyclamide),~~ [[metahexamide]], [[tolazamide]] ~~and~~ [[tolbutamide]].

* 第二世代薬：

* ~~Second-generation drugs:~~

~~They include~~ [[glibenclamide]] ~~(glyburide),~~ [[glibornuride]], [[gliclazide]], [[glipizide]], [[gliquidone]], [[glisoxepide]] ~~and~~ [[glyclopyramide]].

* 第三世代薬：

* ~~Third-generation drugs:~~

[[glimepiride/ja|グリメピリド]]も含まれるが、第2世代薬とみなされることもある。

~~They include~~ [[glimepiride]]~~, although it is sometimes considered a second-generation drug.~~

===~~Mechanism of action~~===

===作用機序===

[[File:Glucose Insulin Release Pancreas.svg|thumb|~~Diagram of glucose reduction and insulin release in the pancreas~~]]

[[File:Glucose Insulin Release Pancreas.svg|thumb|膵臓におけるグルコース減少とインスリン分泌の図]]

~~</div>~~

@@ Line 58: / Line 58: @@
 </gallery>
-<div lang="en" dir="ltr" class="mw-content-ltr">
+===分類===
-===Classification===
+スルホニル尿素は、その抗糖尿病作用の治療効率に基づいて3つのクラスに分類される：
-Sulfonylureas are divided into 3 classes on basis of therapeutic efficiency of their antidiabetic action:
+* 第一世代の薬剤：
-* First-generation drugs:
+[[acetohexamide/ja|アセトヘキサミド]]、[[carbutamide/ja|カルブタミド]]、[[chlorpropamide/ja|クロルプロパミド]]、[[glycyclamide/ja|グリシクラミド]]（トルサイクラミド）、[[metahexamide/ja|メタヘキサミド]]、[[tolazamide/ja|トラザミド]]、[[tolbutamide/ja|トルブタミド]]などがある。
-They include [[acetohexamide]], [[carbutamide]], [[chlorpropamide]], [[glycyclamide]] (tolcyclamide), [[metahexamide]], [[tolazamide]] and [[tolbutamide]].
+* 第二世代薬：
-* Second-generation drugs:
+[[glibenclamide/ja|グリベンクラミド]]（グリブリド）、[[glibornuride/ja|グリボルヌリド]]、[[gliclazide/ja|グリクラジド]]、[[glipizide/ja|グリピジド]]、[[gliquidone/ja|グリキドン]]、[[glisoxepide/ja|グリソキセピド]]、[[glyclopyramide/ja|グリクロピラミド]]などである。
-They include [[glibenclamide]] (glyburide), [[glibornuride]], [[gliclazide]], [[glipizide]], [[gliquidone]], [[glisoxepide]] and [[glyclopyramide]].
+* 第三世代薬：
-* Third-generation drugs:
+[[glimepiride/ja|グリメピリド]]も含まれるが、第2世代薬とみなされることもある。
-They include [[glimepiride]], although it is sometimes considered a second-generation drug.
-===Mechanism of action===
+===作用機序===
-[[File:Glucose Insulin Release Pancreas.svg|thumb|Diagram of glucose reduction and insulin release in the pancreas]]
+[[File:Glucose Insulin Release Pancreas.svg|thumb|膵臓におけるグルコース減少とインスリン分泌の図]]
-</div>
 <div lang="en" dir="ltr" class="mw-content-ltr">