Translations:Glimepiride/16/ja

経口糖尿病治療薬、インスリン製剤およびインスリンアナログ製剤、糖尿病に用いられるその他の薬剤（A10）

超速効型	Insulin aspart/ja Insulin glulisine/ja Insulin lispro/ja
速効型	Regular insulin/ja^#
長時間作用型	Insulin detemir/ja^# インスリングラルギン^# (+リキセナチド) NPH insulin/ja Lente insulin/ja^‡ Ultralente insulin/ja^‡
超長時間作業型	Insulin degludec/ja^# (+インスリンアスパルト, +リラグルチド) Insulin icodec/ja^† (+セマグルチド)
吸入可能	Exubera^‡ Afrezza

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

非インスリン

インスリン感作薬

ビグアナイド	Buformin/ja^‡ メトホルミン^# Phenformin/ja^‡
TZD/"グリタゾン" (PPAR)	Ciglitazone/ja^§ Darglitazone/ja^§ Englitazone/ja^§ Lobeglitazone/ja Netoglitazone/ja^§ Pioglitazone/ja Rivoglitazone/ja^† Rosiglitazone/ja Troglitazone/ja^‡
デュアルPPAR作動薬	Aleglitazar/ja^† Muraglitazar/ja^§ Saroglitazar/ja Tesaglitazar/ja^§
Amylin/jaアナログとDACRA	Cagrilintide/ja^§ Pramlintide/ja

セクレタゴーグ

K⁺_ATP

スルホニル尿素	第一世代: Acetohexamide/ja Carbutamide/ja Chlorpropamide/ja Glycyclamide/ja Metahexamide/ja Tolazamide/ja Tolbutamide/ja 第二世代: グリベンクラミド（グリブリド） Glibornuride/ja Glicaramide/ja Gliclazide/ja^# グリメピリド Glipizide/ja Gliquidone/ja Glisoxepide/ja Glyclopyramide/ja
Meglitinide/ja/"グリニド系"	Mitiglinide/ja Nateglinide/ja Repaglinide/ja

GLP-1受容体作動薬

GLP1ポリアゴニストペプチド	Mazdutide/ja (GLP-1/GCGR) Retatrutide/ja^§ (GLP-1/GIP/GCGR) Tirzepatide/ja (GLP-1/GIP)

DPP-4 阻害薬/"グリプチン"

その他

Aldose reductase inhibitor/ja	Epalrestat/ja Fidarestat/ja^§ Ranirestat/ja^† Tolrestat/ja^‡ Zenarestat/ja^§
Alpha-glucosidase inhibitor/ja	Acarbose/ja Miglitol/ja Voglibose/ja
SGLT2 阻害薬/"グリフロジン"	Canagliflozin/ja Dapagliflozin/ja Empagliflozin/ja^# Ertugliflozin/ja イプラグリフロジン Luseogliflozin/ja レモグリフロジン^§ セルグリフロジン^§ Sotagliflozin/ja Tofogliflozin/ja^† Velagliflozin/ja
その他	Benfluorex/ja^‡ Bromocriptine/ja Imeglimin/ja

配合薬

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Prostanoid/ja 伝達モジュレーター

受容体
(リガンド)

DP (D₂)

DP₁Tooltip Prostaglandin D2 receptor 1/ja	作動薬: プロスタグランジンD₂ Treprostinil/ja 拮抗薬: Asapiprant/ja Laropiprant/ja Vidupiprant/ja
DP₂Tooltip Prostaglandin D2 receptor 2/ja	作動薬: Indometacin/ja プロスタグランジンD₂ 拮抗薬: ADC-3680/ja AZD-1981/ja Bay U3405/ja Fevipiprant/ja MK-1029/ja MK-7246/ja QAV-680/ja Ramatroban/ja Setipiprant/ja Timapiprant/ja TM30089/ja Vidupiprant/ja

EP (E₂)

EP₁Tooltip Prostaglandin EP1 receptor/ja	作動薬: Beraprost/ja Enprostil/ja イロプロスト（シロプロスト） Latanoprost/ja Lubiprostone/ja Misoprostol/ja プロスタグランディンE₁ (alprostadil) プロスタグランディンE₂ (dinoprostone) Sulprostone/ja 拮抗薬: AH-6809/ja ONO-8130/ja SC-19220/ja SC-51089/ja SC-51322/ja
EP₂Tooltip Prostaglandin EP2 receptor/ja	作動薬: Butaprost/ja Misoprostol/ja プロスタグランディンE₁ (alprostadil) プロスタグランディンE₂ (dinoprostone) Treprostinil/ja 拮抗薬: AH-6809/ja PF-04418948/ja TG 4-155/ja
EP₃Tooltip Prostaglandin EP3 receptor/ja	作動薬: Beraprost/ja Carbacyclin/ja Cicaprost/ja Enprostil/ja イロプロスト（シロプロスト） Isocarbacyclin/ja Latanoprost/ja Misoprostol/ja プロスタグランディンD₂ プロスタグランディンE₁ (alprostadil) プロスタグランディンE₂ (dinoprostone) Remiprostol/ja Ricinoleic acid/ja Sulprostone/ja 拮抗薬: L-798106/ja
EP₄Tooltip Prostaglandin EP4 receptor/ja	作動薬: Lubiprostone/ja Misoprostol/ja プロスタグランディンE₁ (alprostadil) プロスタグランディンE₂ (dinoprostone) TCS-2510/ja 拮抗薬: Grapiprant/ja GW-627368/ja L-161982/ja ONO-AE3-208/ja
未分類	作動薬: 16,16-ジメチルプロスタグランディンE₂ Aganepag/ja Carboprost/ja Evatanepag/ja Gemeprost/ja Nocloprost/ja Omidenepag/ja プロスタグランディンF_2α (dinoprost) Simenepag/ja Taprenepag/ja

FP (F_2α)

IP (I₂)

拮抗薬: RO1138452/ja

TP (TX_A2)

未分類

酵素
(阻害剤)

COX (PTGS)	サリチル酸: Aloxiprin/ja アスピリン（アセチルサリチル酸）ベノリレート（ベノリレート） Carbasalate calcium/ja Diflunisal/ja Dipyrocetyl/ja Ethenzamide/ja Guacetisal/ja Magnesium salicylate/ja メサラジン（5-アミノサリチル酸） Methyl salicylate/ja Salacetamide/ja Salicin/ja Salicylamide/ja サリチル酸塩（サリチル酸） Salsalate/ja Sodium salicylate/ja Triflusal/ja; Acetic acids: Aceclofenac Acemetacin/ja Aclofenac/ja Amfenac/ja Alclofenac/ja Bendazac/ja Bromfenac/ja Bufexamac/ja Bumadizone/ja Cinmetacin/ja Clometacin/ja Diclofenac/ja Difenpiramide/ja Etodolac/ja Felbinac/ja Fenclofenac/ja Fentiazac/ja Glucametacin/ja インドメタシン（インドメタシン） Indometacin farnesil/ja Ketorolac/ja Lonazolac/ja Mofezolac/ja Nabumetone/ja Oxametacin/ja Oxindanac/ja Proglumetacin/ja Sulindac/ja Sulindac sulfide/ja Tolmetin/ja Zidometacin/ja Zomepirac/ja; プロピオン酸: Alminoprofen/ja Benoxaprofen/ja ブクロキシ酸（ブルクロキサート） Butibufen/ja Carprofen/ja Dexibuprofen/ja Dexindoprofen/ja Dexketoprofen/ja Fenbufen/ja Fenoprofen/ja Flunoxaprofen/ja Flurbiprofen/ja Ibuprofen/ja Ibuproxam/ja Indoprofen/ja Ketoprofen/ja Loxoprofen/ja Miroprofen/ja Naproxen/ja Naproxcinod/ja Oxaprozin/ja Pirprofen/ja Pranoprofen/ja Suprofen/ja Tarenflurbil/ja Tepoxalin/ja チアプロフェン酸（チアプロフェネート） Vedaprofen/ja; アントラニル酸類（フェナム酸類）: エトフェナム酸（エトフェナマート）フロクタフェン酸（フロクタフェン酸塩）フルフェナム酸（フルフェナマート）メクロフェナム酸（メクロフェナマート）メフェナム酸（メフェナマート）モルニフルミン酸（モルニフルメート）ニフルミン酸（ニフルメート）タリンフルミン酸（タリンフルメート）トルフェナム酸（トルフェナマート）; ピラゾロン: Azapropazone/ja Dipyrone/ja Isopyrin/ja Oxyphenbutazone/ja Phenylbutazone/ja; フェノール酸（オキシカム）: Ampiroxicam/ja Droxicam/ja Enolicam/ja Isoxicam/ja Lornoxicam/ja Meloxicam/ja Piroxicam/ja Tenoxicam/ja; 4-アミノキノリン: Antrafenine/ja Floctafenine/ja Glafenine/ja; キナゾリン: Fluproquazone/ja Proquazone/ja; アミノニコチン酸類: Clonixeril/ja Clonixin/ja Flunixin/ja; スルホナニリド: Flosulide/ja Nimesulide/ja; アミノフェノール（アニリン類）: Acetanilide/ja AM-404 (N-アラキドノイルアミノフェノール) Bucetin/ja パラセタモール（アセトアミノフェン） Parapropamol/ja Phenacetin/ja Propacetamol/ja; 選択的COX-2阻害薬（coxibs）: Apricoxib/ja Celecoxib/ja Cimicoxib/ja Deracoxib/ja Etoricoxib/ja Firocoxib/ja Lumiracoxib/ja Mavacoxib/ja Parecoxib/ja Polmacoxib/ja Robenacoxib/ja Rofecoxib/ja Tilmacoxib/ja Valdecoxib/ja; その他/分類なし: Anitrazafen/ja Clobuzarit/ja Curcumin/ja DuP-697/ja FK-3311/ja Flumizole/ja FR-122047/ja グリメピリド Hyperforin/ja Itazigrel/ja L-655240/ja L-670596/ja Licofelone/ja メナテトレノン (ビタミンK₂) NCX-466/ja NCX-4040/ja NS-398/ja Pamicogrel/ja Resveratrol/ja Romazarit/ja Rosmarinic acid/ja Rutecarpine/ja Satigrel/ja SC-236/ja SC-560/ja SC-58125/ja Tenidap/ja Tiflamizole/ja Timegadine/ja Trifenagrel/ja Tropesin/ja
PGD₂STooltip Prostaglandin D synthase/ja	Retinoid/ja Selenium/ja (selenium tetrachloride/ja, sodium selenite/ja, selenium disulfide/ja)
PGESTooltip Prostaglandin E synthase/ja	HQL-79/ja
PGFSTooltip Prostaglandin F synthase/ja	Bimatoprost/ja
PGI₂STooltip Prostacyclin synthase/ja	Tranylcypromine/ja
TXASTooltip Thromboxane A synthase/ja	Camonagrel/ja Dazmegrel/ja Dazoxiben/ja Furegrelate/ja Isbogrel/ja Midazogrel/ja Nafagrel/ja Nicogrelate/ja Ozagrel/ja Picotamide/ja Pirmagrel/ja Ridogrel/ja Rolafagrel/ja Samixogrel/ja Terbogrel/ja U63557A/ja

その他

こちらも参照: 受容体／シグナルモジュレーター; ロイコトリエンシグナル伝達調節薬

R型選択性: SNX-482/ja

α₂δ サブユニット-選択性 (gabapentinoid/ja): 4-Methylpregabalin/ja
Arbaclofen/ja
Arbaclofen placarbil/ja
Atagabalin/ja
Baclofen/ja
Gabapentin/ja
Gabapentin enacarbil/ja
Imagabalin/ja
Mirogabalin/ja
PD-200,347/ja
PD-217,014/ja
PD-299,685/ja
Phenibut/ja
Pregabalin/ja

活性剤

L型選択性: Bay K8644/ja

カリウム

VGKCs

阻害剤

hERG/ja (KCNH2, K_v11.1)-specific: Ajmaline/ja
Amiodarone/ja
AmmTX3/ja
Astemizole/ja
Azaspiracid/ja
AZD1305/ja
Azimilide/ja
Bedaquiline/ja
BeKm-1
BmTx3/ja
BRL-32872/ja
Chlorpromazine/ja
Cisapride/ja
Clarithromycin/ja
Darifenacin/ja
Dextropropoxyphene/ja
Diallyl trisulfide/ja
Domperidone/ja
E-4031/ja
Ergtoxin/ja
Erythromycin/ja
Gigactonine/ja
Haloperidol/ja
Ketoconazole/ja
Norpropoxyphene/ja
Orphenadrine/ja
Pimozide/ja
PNU-282,987/ja
Promethazine/ja
Quinidine/ja
Ranolazine/ja
Roxithromycin/ja
Sertindole/ja
Solifenacin/ja
Tamulotoxin/ja
Terodiline/ja
Terfenadine/ja
Thioridazine/ja
Tolterodine/ja
Vanoxerine/ja
Vernakalant/ja

KCNQ (K_v7)-specific: Linopirdine/ja
XE-991/ja
スプーキートキシン（SsTx）

活性剤

KCNQ (K_v7)-specific: Flupirtine/ja
Retigabine/ja

IRKs

阻害剤

K_ATPTooltip ATP-sensitive potassium channel/ja-specific: Acetohexamide/ja
Carbutamide/ja
Chlorpropamide/ja
グリベンクラミド（グリブリド）
Glibornuride/ja
Glicaramide/ja
Gliclazide/ja
グリメピリド
Glipizide/ja
Gliquidone/ja
Glisoxepide/ja
Glyclopyramide/ja
Glycyclamide/ja
Metahexamide/ja
Mitiglinide/ja
Nateglinide/ja
Repaglinide/ja
Tolazamide/ja
Tolbutamide/ja

GIRKTooltip G protein-coupled inwardly rectifying potassium channel/ja-specific: Barium/ja
Caramiphen/ja
Cloperastine/ja
Clozapine/ja
Dextromethorphan/ja
Ethosuximide/ja
Ifenprodil/ja
Tertiapin/ja
Tipepidine/ja

活性剤

K_ATPTooltip ATP-sensitive potassium channel/ja-specific: Aprikalim/ja
Bimakalim/ja
Cromakalim/ja
Diazoxide/ja
Emakalim/ja
Levcromakalim/ja
Mazokalim/ja
Minoxidil/ja
Minoxidil sulfate/ja
Naminidil/ja
Nicorandil/ja
Pinacidil/ja
Rilmakalim/ja
Sarakalim/ja

GIRKTooltip G protein-coupled inwardly rectifying potassium channel/ja-specific: ML-297 (VU0456810)

K_Ca

阻害剤	BK_Ca-specific: エタノール（アルコール） GAL-021/ja
活性剤	BK_Ca-specific: Flufenamic acid/ja Meclofenamic acid/ja Niflumic acid/ja Nimesulide/ja ロットレリン（マロトキシン） Tolfenamic acid/ja

K2Ps

阻害剤	12-O-Tetradecanoylphorbol-13-acetate/ja Arachidonic acid/ja Fluoxetine/ja Norfluoxetine/ja
活性剤	Riluzole/ja

ナトリウム

VGSCs

阻害剤

Antianginals: Ranolazine/ja

局所麻酔薬: pFBT
Amylocaine/ja
Articaine/ja
Benzocaine/ja
Bupivacaine/ja (Levobupivacaine/ja, Ropivacaine/ja)
Butacaine/ja
Butamben/ja
Chloroprocaine/ja
Cinchocaine/ja
Cocaine/ja
Cyclomethycaine/ja
Dimethocaine/ja
Diphenhydramine/ja
Etidocaine/ja
Hexylcaine/ja
Iontocaine/ja
Lidocaine/ja
Mepivacaine/ja
Meprylcaine/ja
Metabutoxycaine/ja
Orthocaine/ja
Piperocaine/ja
Prilocaine/ja
Procaine/ja
Propoxycaine/ja
Proxymetacaine/ja
Risocaine/ja
Tetracaine/ja
Trimecaine/ja

活性剤

Aconitine/ja
アトラコトキシン (ω-アトラコトキシン, Robustoxin/ja, Versutoxin/ja)
Batrachotoxin/ja
Ciguatoxin/ja
Grayanotoxin/ja
Poneratoxin/ja

ENaC

阻害剤	Amiloride/ja Benzamil/ja Triamterene/ja
活性剤	Solnatide/ja

ASICs

阻害剤	A-317567/ja Amiloride/ja Aspirin/ja Ibuprofen/ja PcTX1/ja

塩素

CaCCs

阻害剤	Crofelemer/ja DIDS/ja Ethacrynic acid/ja Flufenamic acid/ja Fluoxetine/ja Furosemide/ja Glibenclamide/ja Mefloquine/ja Mibefradil/ja Niflumic acid/ja
活性剤	Carbachol/ja

CFTR

阻害剤	Glibenclamide/ja Lonidamine/ja Piretanide/ja
活性剤	1,7-Phenanthroline/ja 1,10-Phenanthroline/ja 4,7-Phenanthroline/ja 7,8-Benzoquinoline/ja Ivacaftor/ja Phenanthridine/ja

未整理

阻害剤	Bumetanide/ja Flufenamic acid/ja Meclofenamic acid/ja Mefenamic acid/ja Mepacrine/ja Niflumic acid/ja Talniflumate/ja Tolfenamic acid/ja Trifluoperazine/ja

その他

TRPsTooltip Transient receptor potential channels/ja	代わりにここを参照
LGICsTooltip Ligand gated ion channels/ja	代わりにここを参照

こちらも参照: 受容体／シグナル伝達モジュレーター • 一過性受容体電位チャネルモジュレーター