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- 09:05, 4 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/9/ja (Created page with "ピリドキサールリン酸は人体内で数多くの役割を担っている。以下にいくつか例を挙げる： * '''セロトニンの代謝と生合成''' ピリドキサールリン酸は芳香族L-アミノ酸脱炭酸酵素の補要素である。これにより、[[5-Hydroxytryptophan/ja|5-ヒドロキシトリプトファン]...")
- 09:01, 4 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/8/ja (Created page with "== 人体における役割== {{Anchor|Role in human body}} {{Main/ja|Vitamin B6/ja}}")
- 09:01, 4 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/7/ja (Created page with "PLPは、レボドパからドーパミンへの変換に関与し、興奮性神経伝達物質であるグルタミン酸から抑制性神経伝達物質であるGABAへの変換を促進し、SAMを脱炭酸させてポリアミンの前駆体であるプロピルアミンを形成させる。")
- 09:00, 4 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/6/ja (Created page with "また、ヘム合成における縮合反応でも活性を示す。")
- 09:00, 4 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/5/ja (Created page with "PLPは、セリンデヒドラターゼやGDP-4-ケト-6-デオキシマンノース-3-デヒドラターゼ（ColD）が行う反応など、様々なβ-脱離反応にも関与している。")
- 08:59, 4 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/4/ja (Created page with "トランスアミノ化では、脱プロトン化後にキノノイド中間体が別の位置でプロトンを受け入れ、ケチミンとなる。得られたケチミンは加水分解され、アミノ基が複合体上に残る。さらに、PLPはペルオサミンやデソサミンのような珍しい糖に作用するアミノトランスフェラーゼ（またはトランスアミナーゼ）によって...")
- 08:59, 4 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/3/ja (Created page with "==補酵素としての役割== {{Anchor|Role as a coenzyme}} PLPはすべてのトランスアミノ化反応、および特定の脱炭酸、脱アミノ化、アミノ酸のラセミ化反応において補酵素として働く。 PLPのアルデヒド基は、アミノトランスフェラーゼ酵素の特定のリジン基のε-アミノ基...")
- 21:39, 3 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/30/ja (Created page with "== こちらも参照 == *Aromatic-L-amino-acid decarboxylase/ja *Ornithine decarboxylase/ja")
- 21:38, 3 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/31/ja (Created page with "== 外部リンク == * {{ATC|A11|HA06}}")
- 21:38, 3 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/32/ja (Created page with "{{Vitamin/ja}} {{Enzyme cofactors/ja}}")
- 21:38, 3 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/33/ja (Created page with "{{DEFAULTSORT:Pyridoxal Phosphate}} Category:B vitamins Category:Organophosphates Category:3-Hydroxypropenals Category:Aromatic ketones")
- 21:38, 3 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/2/ja (Created page with "'''ピリドキサールリン酸'''（'''PLP'''、ピリドキサール5'-リン酸、'''P5P'''）は、ビタミンB<sub>6</sub>の活性型であり、様々な酵素反応における補酵素である。国際生化学分子生物学連合は140以上のPLP依存性活性をカタログ化しており、分類され...")
- 21:36, 3 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/1/ja (Created page with "{{chembox | Verifiedfields = changed | verifiedrevid = 393759663 | ImageFile_Ref = {{chemboximage|correct|??}} | ImageFile = Pyridoxal-phosphate.svg | ImageSize = | ImageName = Skeletal formula | ImageCaption = 理想化された骨格式 | ImageFile1 = Pyridoxal-phosphate-from-xtal-3D-bs-17.png | ImageSize1 = 210px | ImageName1 = Ball-and-stick model | ImageCaption1 = 結晶構造に基づくBall-and-stick model/ja|ボ...")
- 21:36, 3 April 2024 Fire talk contribs created page Pyridoxal phosphate/ja (Created page with "ピリドキサールリン酸") Tags: Mobile edit Mobile web edit
- 21:35, 3 April 2024 Fire talk contribs created page Translations:Pyridoxal phosphate/Page display title/ja (Created page with "ピリドキサールリン酸")
- 21:34, 3 April 2024 Fire talk contribs marked Pyridoxal phosphate for translation
- 21:34, 3 April 2024 Fire talk contribs limited languages for translatable page Pyridoxal phosphate to Japanese
- 21:33, 3 April 2024 Fire talk contribs created page Category:Aromatic ketones (Created page with "{{Commonscat}} Category:Aromatic compounds Category:Ketones {{CatAutoTOC}}")
- 21:33, 3 April 2024 Fire talk contribs created page Category:3-Hydroxypropenals (Created page with "{{cat main|Malondialdehyde}} Category:Beta-hydroxy ketones Category:Enones")
- 21:30, 3 April 2024 Fire talk contribs created page pyridoxal phosphate transmembrane transporter activity (Q21781) (wbeditentity-create:2|en: pyridoxal phosphate transmembrane transporter activity, Enables the directed movement of pyridoxal phosphate into, out of or within a cell, or between cells; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.)
- 21:28, 3 April 2024 Fire talk contribs created page pyridoxamine metabolic process (Q21780) (wbeditentity-create:2|en: pyridoxamine metabolic process, The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the b)
- 21:24, 3 April 2024 Fire talk contribs created page pyridoxal phosphate metabolic process (Q21779) (wbeditentity-create:2|en: pyridoxal phosphate metabolic process, The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.)
- 21:23, 3 April 2024 Fire talk contribs created page pyridoxal phosphate biosynthetic process (Q21778) (wbeditentity-create:2|en: pyridoxal phosphate biosynthetic process, The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.)
- 21:21, 3 April 2024 Fire talk contribs created page pyridoxal 5'-phosphate salvage (Q21777) (wbeditentity-create:2|en: pyridoxal 5'-phosphate salvage, Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis.)
- 21:20, 3 April 2024 Fire talk contribs created page pyridoxal phosphate biosynthetic process from pyridoxamine (Q21776) (wbeditentity-create:2|en: pyridoxal phosphate biosynthetic process from pyridoxamine, The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine.)
- 21:13, 3 April 2024 Fire talk contribs created page pyridoxal phosphate (Q21775) (wbeditentity-create:2|en: pyridoxal phosphate, chemical compound)
- 21:09, 3 April 2024 Fire talk contribs created page Template:Enzyme cofactors/ja (Created page with "{{Navbox | name = Enzyme cofactors/ja | title = 酵素補要素 | state = {{{state|autocollapse}}} | listclass = hlist | group1 = アクティブ・フォーム | list1 = {{Navbox|subgroup | group1 = vitamin/ja | list1 = * TPP / ThDP (B<sub>1</sub>) * FMN, FAD (B<sub>2</sub>) * Nicotinamide adenine dinucleotide/ja|...")
- 21:05, 3 April 2024 Fire talk contribs created page Template:Enzyme cofactors (Created page with "{{Navbox | name = Enzyme cofactors | title = Enzyme cofactors | state = {{{state|autocollapse}}} | listclass = hlist | group1 = Active forms | list1 = {{Navbox|subgroup | group1 = vitamins | list1 = * TPP / ThDP (B<sub>1</sub>) * FMN, FAD (B<sub>2</sub>) * NAD<sup>+</sup>, Nicotinamide adenine dinuc...")
- 21:04, 3 April 2024 Fire talk contribs created page Pyridoxal phosphate (Created page with "{{short description|Active form of vitamin B6}} {{chembox | Verifiedfields = changed | verifiedrevid = 393759663 | ImageFile_Ref = {{chemboximage|correct|??}} | ImageFile = Pyridoxal-phosphate.svg | ImageSize = | ImageName = Skeletal formula | ImageCaption = Idealised skeletal formula | ImageFile1 = Pyridoxal-phosphate-from-xtal-3D-bs-17.png | ImageSize1 = 210px | ImageName1 = Ball-and-stick model | ImageCaption1 = Ball-and-stick model based on the crystal stru...")
- 20:57, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/12/ja (Created page with "==代謝== {{Anchor|Metabolism}} ある情報源では、''ピリドキシン''の半減期は最大20日とされているが、別の情報源では、''ビタミンB<sub>6</sub>''の半減期は25～33日とされている。異なる情報源を考慮した結果、ピリドキシンの半減期は通常数週間であると結論づけられる。")
- 20:56, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/11/ja (Created page with "==メカニズム== {{Anchor|Mechanism}} ピリドキシンはビタミンBの仲間である。体内でアミノ酸、炭水化物、脂質を作るのに必要である。食事中の供給源としては果物、野菜、穀物などがある。 グリコーゲン代謝に関連する筋ホスホリラーゼ活性にも必要である。")
- 20:55, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/10/ja (Created page with "==副作用== {{Anchor|Side effects}} 通常、忍容性は高いが、過剰摂取による毒性はあり得る。時折、頭痛、しびれ、眠気などの副作用が現れる。 ピリドキシンの過剰摂取は、協調性の低下、しびれ、触覚、温度、振動に対する感覚の低下を特徴とする末梢感覚神経障害を引き起こす可能性がある。健康なヒトのピリドキシンの血中濃度は2.1～21.7 ng/mLである...")
- 20:55, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/9/ja (Created page with "ピリドキシンとドキシラミンの併用は、妊婦のつわりの治療薬として用いられる。")
- 20:54, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/8/ja (Created page with "==医薬用途== {{Anchor|Medical uses}} 治療薬（経口薬または注射薬）として、ピリドキシン欠乏症、鉄芽球性貧血、ピリドキシン依存性てんかん、特定の代謝異常、イソニアジド治療の副作用、およびある種のキノコ中毒の治療または予...")
- 20:52, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/13/ja (Created page with "==歴史== {{Anchor|History}} ピリドキシンは1934年に発見され、1938年に単離され、1939年に初めて製造された。ピリドキシンはWHO必須医薬品リストに掲載されている。ピリドキシンはジェネリック医薬品としても市販薬としても入手可能である。朝食用シリアルなどの食品...")
- 20:51, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/14/ja (Created page with "== 外部リンク == * {{Commons category-inline}} * {{cite web| url = https://druginfo.nlm.nih.gov/drugportal/name/pyridoxine | publisher = U.S. National Library of Medicine| work = Drug Information Portal| title = Pyridoxine }} * [http://gmd.mpimp-golm.mpg.de/Spectrums/73e34958-2680-41b1-a8d7-40e1650703bc.aspx Pyridoxine mass spectrum]")
- 20:51, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/15/ja (Created page with "{{Vitamin/ja}} {{Portal bar|Medicine}}")
- 20:51, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/16/ja (Created page with "Category:B vitamins Category:Hydroxypyridines Category:World Health Organization essential medicines Category:Wikipedia medicine articles ready to translate Category:Cofactors Category:Primary alcohols Category:Triols")
- 20:50, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/7/ja (Created page with "<!-- Side effects and mechanism --> 通常、忍容性は良好である。時折、副作用として頭痛、しびれ、眠気が起こる。通常の用量であれば、妊娠中や授乳中でも安全である。ピリドキシンはビタミンのビタミンB族に属する。体内でアミノ酸、炭水化物、脂質を代謝するのに必要であ...")
- 20:49, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/6/ja (Created page with "<!-- Definition and medical uses --> '''ピリドキシン'''（'''Pyridoxine'''）は、ビタミンB<sub>6</sub>の一種で、食品によく含まれ、栄養補助食品として使用される。サプリメントとしては、ピリドキシン欠乏症、鉄芽球性貧血、ピリドキシン依存性てんかん、特定の...")
- 20:47, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/5/ja (Created page with "<!-- Identifiers --> | CAS_number = 65-23-6 | CAS_supplemental = | PubChem = 1054 | PubChemSubstance = | IUPHAR_ligand = | DrugBank = DB00165 | ChemSpiderID = 1025 | UNII = KV2JZ1BI6Z | KEGG = D08454 | ChEBI = 16709 | ChEMBL = 1364 | NIAID_ChemDB = | synonyms = vitamin B<sub>6</sub>, pyridoxol pyridoxine hydrochloride <!-- Chemical and physical data --> | chemical_formula...")
- 20:47, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/4/ja (Created page with "<!-- Pharmacokinetic data --> | bioavailability = | protein_bound = | metabolism = | metabolites = | onset = | elimination_half-life = 数週間（詳細は#代謝を参照のこと） | duration_of_action = | excretion =")
- 20:47, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/3/ja (Created page with "| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> | legal_AU_comment = | legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_CA_comment = | legal_DE = <!-- Anlage I, II, III or Unscheduled--> | legal_DE_comment = | legal_NZ = <!-- Class A, B, C --> | legal_NZ_comment = | legal_UK = P | legal_UK_comment = | legal_US = OTC | legal_US_comment = / Rx-only | legal_UN = <!-- N I, II, III, IV / P I, II, III, IV--> | legal_U...")
- 20:46, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/2/ja (Created page with "<!-- Clinical data --> | pronounce = | tradename = | Drugs.com = {{Drugs.com|monograph|pyridoxine-hydrochloride}} | MedlinePlus = | licence_EU = <!-- EMA requires brand name --> | licence_US = <!-- FDA may use generic name --> | DailyMedID = Pyridoxine | pregnancy_AU = | pregnancy_AU_comment = Exempt | pregnancy_category= | dependency_liability = | addiction_liability = | routes_of_administration = By mouth, intrave...")
- 20:46, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/1/ja (Created page with "{{Infobox drug | drug_name = | INN = | type =<!-- empty --> | IUPAC_name = 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol | image = Pyridoxin.svg | width = | alt = | image2 = Pyridoxine-from-xtal-3D-bs-17.png | width2 = | alt2 = | caption = ピリドキシン")
- 20:46, 3 April 2024 Fire talk contribs created page Pyridoxine/ja (Created page with "ピリドキシン")
- 20:46, 3 April 2024 Fire talk contribs created page Translations:Pyridoxine/Page display title/ja (Created page with "ピリドキシン")
- 20:46, 3 April 2024 Fire talk contribs marked Pyridoxine for translation
- 20:46, 3 April 2024 Fire talk contribs limited languages for translatable page Pyridoxine to Japanese
- 20:42, 3 April 2024 Fire talk contribs created page visual epilepsy (Q21774) (wbeditentity-create:2|en: visual epilepsy, Human disease)