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Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 19:28, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/18/ja (Created page with "==薬理学{{Anchor|Pharmacology}}== 摂取後、エイコサペンタエン酸エチル（E-EPA）はエイコサペンタエン酸（EPA）に代謝される。EPAは小腸で吸収され、循環に入る。血漿中濃度のピークは摂取後約5時間で、半減期は約89時間である。EPAは主に肝臓で脂肪分解される。")
- 19:27, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/17/ja (Created page with "== 副作用{{Anchor|Side effects}}== 魚介類アレルギーのある人は特に注意が必要である。また、他のオメガ3脂肪酸と同様に、エイコサペンタエン酸エチル（E-EPA）を摂取すると、抗凝固薬を服用している人は出血時間が延長するリスクがある。 臨床試験で最も多く報告された副作用は関節痛であり、口や喉の痛み...")
- 19:27, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/16/ja (Created page with "===栄養補助食品=== 海産物をベースとしたオメガ3系サプリメントには、心血管疾患や早死を抑制する効果があることが示唆されている。 これらの効果は、糖尿病患者のような他の集団では発揮されないかもしれない。 栄養補助食品の成分は、処方薬ほど注意深く管理されておらず、処方薬のように臨床試験で固定されテストされていない、 また、処方...")
- 19:26, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/15/ja (Created page with "* オメガ-3-酸エチルエステル（商品名オマコール［米国ではアミカーやオムトリグとの混同を避けるためロバザに改称］）、2016年3月現在、4種類のジェネリック医薬品がある。 * オメガ-3カルボン酸（Epanova）；Epanovaの商品名は米国で販売中止となった。")
- 19:25, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/14/ja (Created page with "オメガ3系魚油をベースにした薬物は他にもあり、用途や作用機序が似ている：")
- 19:23, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/13/ja (Created page with "=== その他の魚油ベースの薬物===")
- 19:23, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/12/ja (Created page with "一般に、トリグリセリドを有意に（15％以上）低下させるためには、処方薬物または栄養補助食品として長鎖オメガ-3脂肪酸を大量（2.0～4.0g/日）摂取する必要があり、その摂取量では、その効果は有意（20％～35％、500 mg/dLを超える人では最大45％）になる可能性がある。エイコサペンタエン酸（EPA）とドコサヘキサエン酸（DHA）の両方がトリグリセ...")
- 19:22, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/11/ja (Created page with "米国では、イコサペントエチルは、トリグリセリド値が高く（150 mg/dL以上）、心血管疾患または糖尿病が確立しており、さらに2つ以上の心血管疾患の危険因子を有する成人において、心筋梗塞、脳卒中、冠動脈血行再建術、入院を要する不安定狭心症のリスクを軽減するために、最大限の忍容性を有するスタチン療法の補助薬として適応されている...")
- 19:22, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/27/ja (Created page with "== 社会と文化{{Anchor|Society and culture}} == === 法的地位=== 2021年1月28日、欧州医薬品庁（EMA）のヒト用医薬品委員会（CHMP）は、心血管リスクが高い人の心血管イベントリスク軽減を目的とした医薬品バズケパの販売承認を推奨する肯定的意見を採択した。この医薬品の申請者はAmarin Pharmaceuticals社である。アイルランド・リミテッ...")
- 19:21, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/28/ja (Created page with "{{Lipid modifying agents/ja}} {{Portal bar | Medicine}}")
- 19:21, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/29/ja (Created page with "{{DEFAULTSORT:Ethyl Eicosapentaenoic Acid}} Category:Biochemistry Category:Ethyl esters Category:Fatty acid esters Category:Polyolefins Category:Treatment of bipolar disorder Category:Fish products Category:Hypolipidemic agents")
- 19:20, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/10/ja (Created page with "==医療用途{{Anchor|Medical uses}}== 欧州連合（EU）では、イコサペントエチルはスタチン療法の補助として心血管リスクを軽減する効能である。")
- 19:19, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/9/ja (Created page with "オメガ3脂肪酸から作られる。エイコサペンタエン酸（EPA）を原料としている。米国食品医薬品局（FDA）は2012年、アマリン社にイコサペントエチルの承認を与え、オメガ3酸エチルエステル（商品名Lovaza、それ自体は2004年に承認）に次ぐ2番目の魚油ベースの医薬品となった。...")
- 19:18, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/8/ja (Created page with "最も一般的な副作用は、筋骨格痛、末梢性浮腫（脚や手のむくみ）、心房細動、関節痛（関節の痛み）である。その他の一般的な副作用としては、出血、便秘、痛風、発疹などがある。")
- 19:18, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/7/ja (Created page with "'''エイコサペンタエン酸エチル'''（'''E-EPA'''、'''icosapent ethyl'''）は、脂質異常症および高トリグリセリド血症の治療に用いられる医薬品である。150 mg/dL以上の高トリグリセリド血症の成人には、食事の変更と併用して使用される。さらに、スタチン（最大耐用量）との併用が求められることが多い。")
- 19:17, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/6/ja (Created page with "<!-- Chemical and physical data --> | IUPAC_name = Ethyl (5''Z'',8''Z'',11''Z'',14''Z'',17''Z'')-icosa-5,8,11,14,17-pentaenoate | C=22 | H=34 | O=2 | SMILES = CCC=CCC=CCC=CCC=CCC=CCCCC(=O)OCC | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C22H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h5-6,8-9,11-12,14-15,17-18H,3-4,7,10,13,16,19-21H2,1-2H3/b6-5-,9-8-,12-11-,15-14-,18-17- | StdInChI_comment...")
- 19:17, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/5/ja (Created page with "<!-- Identifiers --> | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 86227-47-6 | CAS_supplemental = | PubChem = 9831415 | IUPHAR_ligand = 7441 | DrugBank_Ref = | DrugBank = DB08887 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 8007147 | UNII_Ref = | UNII = 6GC8A4PAYH | KEGG_Ref = | KEGG = D01892 | KEGG2_Ref = | KEGG2 =...")
- 19:17, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/4/ja (Created page with "<!-- Pharmacokinetic data --> | bioavailability = | protein_bound = | metabolism = | metabolites = | onset = | elimination_half-life = | duration_of_action = | excretion =")
- 19:16, 15 April 2024 Fire talk contribs created page Ethyl eicosapentaenoic acid/ja (Created page with "<!-- Clinical data --> | pronounce = | tradename = Vascepa, Vazkepa | Drugs.com = {{drugs.com|monograph|icosapent-ethyl}} | MedlinePlus = a613024 | licence_CA = <!-- Health Canada may use generic or brand name (generic name preferred) --> | licence_EU = yes | DailyMedID = Icosapent_ethyl | licence_US = Vascepa | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = [...")
- 19:16, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/3/ja (Created page with "<!-- Legal status --> | legal_AU = S4 | legal_AU_comment = | legal_BR = <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F--> | legal_BR_comment = | legal_CA = Rx-only | legal_CA_comment = | legal_DE = <!-- Anlage I, II, III or Unscheduled--> | legal_DE_comment = | legal_NZ = <!-- Class A, B, C --> | legal_NZ_comment = | legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C --> | legal...")
- 19:16, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/2/ja (Created page with "<!-- Clinical data --> | pronounce = | tradename = Vascepa, Vazkepa | Drugs.com = {{drugs.com|monograph|icosapent-ethyl}} | MedlinePlus = a613024 | licence_CA = <!-- Health Canada may use generic or brand name (generic name preferred) --> | licence_EU = yes | DailyMedID = Icosapent_ethyl | licence_US = Vascepa | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = [...")
- 19:16, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/1/ja (Created page with "{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | drug_name = | INN = | type = <!-- empty --> | image = Ethyl eicosapentaenoate.png | width = 200 | alt = | caption = | USAN = Icosapent ethyl")
- 19:16, 15 April 2024 Fire talk contribs created page Translations:Ethyl eicosapentaenoic acid/Page display title/ja (Created page with "イコサペント酸エチル")
- 19:16, 15 April 2024 Fire talk contribs marked Ethyl eicosapentaenoic acid for translation
- 19:16, 15 April 2024 Fire talk contribs limited languages for translatable page Ethyl eicosapentaenoic acid to Japanese
- 19:14, 15 April 2024 Fire talk contribs created page Template:ParameterUseFirst (Redirected page to Template:If empty) Tag: New redirect
- 19:13, 15 April 2024 Fire talk contribs created page Category:Fish products (Created page with "Category:Animal products Products")
- 19:13, 15 April 2024 Fire talk contribs created page Category:Treatment of bipolar disorder (Created page with "{{Commons}} {{Cat main}} Category:Bipolar disorder Bipolar Disorder Bipolar")
- 19:12, 15 April 2024 Fire talk contribs created page Category:Polyolefins (Created page with "{{Cat main|Polyolefin}} {{Commons category}} Category:Organic polymers Category:Alkenes")
- 19:12, 15 April 2024 Fire talk contribs created page Category:Fatty acid esters (Created page with "{{Commons category|Fatty acid esters}} Category:Carboxylate esters Category:Fatty acid derivatives")
- 19:12, 15 April 2024 Fire talk contribs created page Category:Ethyl esters (Created page with "'''Ethyl esters''' are esters of ethanol. {{Commons cat|Ethyl esters}} Category:Alkyl esters Category:Ethoxy compounds")
- 19:11, 15 April 2024 Fire talk contribs created page Category:Infobox drug with local INN variant (Created page with "{{hidden category}} Drugs that have a local INN variant, different from INN. Local variants are used by: AAN (Australia), BAN (UK, commonwealth), JAN (Japan), USAN (US). Populated by {{tl|Infobox drug}}, when any parameter {{para|1=AAN=, BAN=, JAN=, USAN}} has input. Category:Infobox drug tracking categories")
- 19:10, 15 April 2024 Fire talk contribs created page platelet aggregation inhibitors (Q22054) (wbeditentity-create:2|en: platelet aggregation inhibitors, class of pharmaceuticals that decrease platelet aggregation and inhibit thrombus formation)
- 15:39, 15 April 2024 Fire talk contribs created page wax-ester hydrolase activity (Q22053) (wbeditentity-create:2|en: wax-ester hydrolase activity, Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.)
- 15:38, 15 April 2024 Fire talk contribs created page long-chain-alcohol O-fatty-acyltransferase activity (Q22052) (wbeditentity-create:2|en: long-chain-alcohol O-fatty-acyltransferase activity, Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA.)
- 15:37, 15 April 2024 Fire talk contribs created page wax ester (Q22051) (wbeditentity-create:2|en: wax ester, ester of a fatty acid and a fatty alcohol)
- 15:36, 15 April 2024 Fire talk contribs created page wax monoester (Q22050) (wbeditentity-create:2|en: wax monoester, class of chemical compounds)
- 15:34, 15 April 2024 Fire talk contribs created page icosapent ethyl (Q22049) (wbeditentity-create:2|en: icosapent ethyl, chemical compound)
- 15:31, 15 April 2024 Fire talk contribs created page Template:Infobox drug/localINNvariants (Created page with "{{trim|1={{#invoke:String |replace| source={{{synonyms|}}}<!-- -->{{#if:{{{AAN|}}} |, {{{AAN}}} (AAN <small>{{abbr|AU|Australia}}</small>)}}<!-- -->{{#if:{{{BAN|}}} |, {{{BAN}}} (BAN <small>{{abbr|UK|United Kingdom}}</small>) }}<!-- -->{{#if:{{{JAN|}}} |, {{{JAN}}} (JAN <small>{{abbr|JP|Japan}}</small>) }}<!-- -->{{#if:{{{USAN|}}} |, {{{USAN}}} (USAN <small...")
- 15:30, 15 April 2024 Fire talk contribs created page Antilipemic Agents/ja (Redirected page to 脂質低下薬) Tag: New redirect
- 15:30, 15 April 2024 Fire talk contribs created page Antilipemic Agents (Redirected page to Lipid-lowering agent) Tag: New redirect
- 15:29, 15 April 2024 Fire talk contribs created page Ethyl eicosapentaenoic acid (Created page with "{{Short description|Medication}} {{Infobox drug | Verifiedfields = changed | Watchedfields = changed | drug_name = | INN = | type = <!-- empty --> | image = Ethyl eicosapentaenoate.png | width = 200 | alt = | caption = | USAN = Icosapent ethyl <!-- Clinical data --> | pronounce = | tradename = Vascepa, Vazkepa | Drugs.com = {{drugs.com|mono...")
- 14:58, 15 April 2024 Fire talk contribs marked Lipid-lowering agent for translation
- 14:53, 15 April 2024 Fire talk contribs marked Lipid-lowering agent for translation
- 21:31, 14 April 2024 Fire talk contribs created page Translations:Docosahexaenoic acid/30/ja (Created page with "===魚油に含まれるDHAとEPA=== 魚油は、EPAとDHAを含むオメガ3脂肪酸の混合物を含むカプセルで広く販売されている。サプリメントカプセルに含まれる酸化された魚油は、EPAとDHAのレベルが低いかもしれない。光、酸素への暴露、熱はすべて魚油サプリメントの酸化の原因となる。保管時に低温に保たれている高品質の製品を...")
- 21:30, 14 April 2024 Fire talk contribs created page Translations:Docosahexaenoic acid/29/ja (Created page with "===ベジタリアンとビーガンの研究==== {{Main/ja|Vegetarian nutrition/ja#Omega-3 fatty acids}} ベジタリアンの食事に含まれるDHAの量は限られており、ビーガンの食事にはDHAが含まれないのが一般的である。予備研究では、藻類をベースとしたサプリメントはDHA濃度を増加させた。成人のベジタリアンやビーガンにおけるDHA欠乏...")
- 21:29, 14 April 2024 Fire talk contribs created page Translations:Docosahexaenoic acid/28/ja (Created page with "製造されたDHAの中には、藻類から抽出されたベジタリアン製品もあり、DHAやEPAなどの他のオメガ3を含む魚油と市場で競合している。魚油もDHAも、食品添加物として加工された後は無味無臭である。")
- 21:29, 14 April 2024 Fire talk contribs created page Translations:Docosahexaenoic acid/27/ja (Created page with "===食品添加物としての利用=== DHAは食品サプリメントとして広く利用されている。最初は主に乳児用ミルクに使用されていた。2019年、米国食品医薬品局はDHAの適格ヘルスクレームを公表した。")
- 21:28, 14 April 2024 Fire talk contribs created page Translations:Docosahexaenoic acid/26/ja (Created page with "===藻類由来のDHAの発見=== 1980年代初頭、NASAは長期間の宇宙飛行で酸素と栄養を生成できる植物ベースの食物源に関する科学的研究を後援した。ある種の海洋藻類は豊富な栄養素を生産し、DHAとアラキドン酸という2つの多価不飽和脂肪酸を含む藻類ベースの植物性オイルの開発につながった。")
- 21:27, 14 April 2024 Fire talk contribs created page Translations:Docosahexaenoic acid/25/ja (Created page with "食品として摂取される哺乳類の脳も、直接摂取するのに適している。例えば牛の脳には、100gあたり約855mgのDHAが含まれている。DHAはある種の特殊な組織で見られる主要な脂肪酸かもしれないが、脳は別として、これらの組織は通常、精細管や網膜のようにサイズが小さい。そのため、脳を除いた動物性食品に含まれるDHAの量は、一般的に...")