Main public logs

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17:59, 5 April 2024 Fire talk contribs created page Translations:Folinic acid/6/ja (Created page with " | IUPAC_name = (''2S'')-2-<nowiki/>{[4-[(2-amino-5-formyl-4-oxo-5,6,7,8- tetrahydro-1''H''-pteridin-6-yl)methylamino] benzoyl]amino}pentanedioic acid | C=20 | H=23 | N=7 | O=7 | SMILES = O=C(O)[C@@H](NC(=O)c1ccc(cc1)NCC3N(/C2=C(/N/C(=N\C2=O)N)NC3)C=O)CCC(=O)O | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h...")
17:59, 5 April 2024 Fire talk contribs created page Translations:Folinic acid/5/ja (Created page with " | IUPHAR_ligand = 4816 | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 1492-18-8 | PubChem = 6006 | DrugBank_Ref = {{drugbankcite|changed|drugbank}} | DrugBank = DB00650 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 5784 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = RPR1R4C0P4 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 1679 | synonyms = citrovorum factor, 5-formyltetrahydrofolate")
17:58, 5 April 2024 Fire talk contribs created page Translations:Folinic acid/4/ja (Created page with " | bioavailability = Dose dependent | protein_bound = ~15% | metabolism = | elimination_half-life = 6.2 hours | excretion = Kidney/ja")
17:58, 5 April 2024 Fire talk contribs created page Translations:Folinic acid/3/ja (Created page with " | legal_AU =  | legal_AU_comment = | legal_BR =  | legal_BR_comment = | legal_CA =  | legal_CA_comment = | legal_DE =  | legal_DE_comment = | legal_NZ =  | legal_NZ_comment = | legal_UK = <!-- GSL, P, POM,...")
17:58, 5 April 2024 Fire talk contribs created page Translations:Folinic acid/2/ja (Created page with " | pronounce = Leucovorin {{IPAc-en|ˌ|lj|uː|k|oʊ|ˈ|v|ɔː|r|ɪ|n}} | tradename = Many | Drugs.com = {{drugs.com|monograph|leucovorin-calcium}} | MedlinePlus = a608038 | DailyMedID = Leucovorin calcium | pregnancy_AU = A | routes_of_administration = 静脈内注射, IM, 口から | ATC_prefix = V03 | ATC_suffix = AF03")
17:58, 5 April 2024 Fire talk contribs created page Translations:Folinic acid/1/ja (Created page with "{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 470454241 | image = Folinic acid.svg | alt = フォリン酸の骨格式 | width = 250 | image2 = Leucovorin molecule ball.png | alt2 = フォリン酸分子のボール＆スティック・モデル")
17:57, 5 April 2024 Fire talk contribs created page Translations:Folinic acid/Page display title/ja (Created page with "フォリン酸")
17:57, 5 April 2024 Fire talk contribs marked Folinic acid for translation
17:57, 5 April 2024 Fire talk contribs limited languages for translatable page Folinic acid to Japanese
17:55, 5 April 2024 Fire talk contribs created page Category:Chemotherapeutic adjuvants (Created page with "{{Detoxifying agents for antineoplastic treatment|state=collapsed}} {{Commons cat|Chemotherapeutic adjuvants}} {{Cat main|Adjuvant therapy}} Category:Antineoplastic drugs")
17:52, 5 April 2024 Fire talk contribs created page 5-formyltetrahydrofolate transport (Q21793) (wbeditentity-create:2|en: 5-formyltetrahydrofolate transport, The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore.)
17:51, 5 April 2024 Fire talk contribs created page 5-formyltetrahydrofolate transmembrane transporter activity (Q21792) (wbeditentity-create:2|en: 5-formyltetrahydrofolate transmembrane transporter activity, Enables the directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells.)
17:49, 5 April 2024 Fire talk contribs created page lactam (Q21791) (wbeditentity-create:2|en: lactam, class of chemical compounds)
17:47, 5 April 2024 Fire talk contribs created page benzamide (Q21790) (wbeditentity-create:2|en: benzamide, any chemical compound with benzamido group)
17:45, 5 April 2024 Fire talk contribs created page folinic acid (Q21789) (wbeditentity-create:2|en: folinic acid, group of stereoisomers)
17:42, 5 April 2024 Fire talk contribs created page Template:Detoxifying agents for antineoplastic treatment/ja (Created page with "{{Navbox | name = Detoxifying agents for antineoplastic treatment/ja | title = 化学療法治療におけるデトックス (V03AF) | state = {{{state<includeonly>|autocollapse</includeonly>}}} | listclass = hlist | group1 = Folic acid/ja / methotrexate/ja | list1 = * フォリン酸の塩 ** 葉酸カルシウム／レボホリナートカルシウム ** 葉酸ナト...")
17:37, 5 April 2024 Fire talk contribs created page Template:Detoxifying agents for antineoplastic treatment (Created page with "{{Navbox | name = Detoxifying agents for antineoplastic treatment | title = Detoxifying agents for chemotherapy treatment (V03AF) | state = {{{state<includeonly>|autocollapse</includeonly>}}} | listclass = hlist | group1 = Folic acid / methotrexate | list1 = * Salts of Folinic acid ** calcium folinate/calcium levofolinate ** sodium folinate/sodium levofolinate | group2 = Uric acid (Tumor lysis syndr...")
17:37, 5 April 2024 Fire talk contribs created page Folinic acid (Created page with "{{Short description|Derivative of folic acid used in cancer treatment}} {{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 470454241 | image = Folinic acid.svg | alt = Skeletal formula of folinic acid | width = 250 | image2 = Leucovorin molecule ball.png | alt2 = Ball-and-stick model of the folinic acid molecule  | pronounce = Leucovorin {{IPAc-en|ˌ|lj|uː|k|oʊ|ˈ|v|ɔː|r|ɪ|n}} | tradename = Many | Drugs.com = {{dr...")
16:24, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/9/ja (Created page with "Category:EC 6.3.2 Category:Enzymes of known structure")
16:24, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/8/ja (Created page with "{{Ligases CO CS and CN/ja}} {{Enzymes/ja}} {{Portal bar|Biology|border=no}}")
16:24, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/7/ja (Created page with "==参照== * {{cite journal | vauthors = GRIFFIN MJ, BROWN GM | title = The Biosynthesis of Folic Acid. III. Enzymatic Formation of Dihydrofolic Acid from Dihydropteroic Acid and of Tetrahydropteroylpolyglutamic Acid Compounds from Tetrahydrofolic Acid | date = 1964 | journal = J. Biol. Chem. | volume = 239 | pages = 310–6 | doi = 10.1016/S0021-9258(18)51783-X | pmid = 14114858 | doi-access = free }} * {{cite journal | vauthors = Bognar AL, Osborne C, Shane B, Si...")
16:23, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/6/ja (Created page with "2007年末現在、このクラスの酵素については3つの構造が解明されており、PDBのアクセッションコードは{{PDB link|1W78}}、{{PDB link|1W7K}}、{{PDB link|2BMB}}である。")
16:23, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/5/ja (Created page with "==構造研究== {{Anchor|Structural studies}}")
16:23, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/4/ja (Created page with "この酵素はリガーゼのファミリーに属し、特に酸-D-アミノ酸リガーゼ（ペプチド合成酵素）として炭素-窒素結合を形成する。この酵素クラスの|系統名は'''7,8-ジヒドロテロエート:L-グルタミン酸リガーゼ（ADP形成）'''である。その他の一般的な名称としては、'''ジヒドロ葉酸合成酵素'''、'''7,8-ジヒドロ葉酸合成酵素'''、'''H2-...")
16:20, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/3/ja (Created page with "この酵素の3つの基質はATP、7,8-ジヒドロテロエート、L-グルタミン酸であり、3つの産物はADP、リン酸、7,8-ジヒドロテロイルグルタミン酸である。")
16:18, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/2/ja (Created page with ":ATP + 7,8-dihydropteroate + L-glutamate <math>\rightleftharpoons</math> ADP + phosphate + 7,8-dihydropteroylglutamate")
16:18, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/1/ja (Created page with "{{infobox enzyme | Name = ジヒドロ葉酸合成酵素 | EC_number = 6.3.2.12 | CAS_number = 37318-62-0 | GO_code = 0008841 | image = 1w7k.jpg | width = 270 | caption = ジヒドロ葉酸合成酵素モノマー, 大腸菌 }} 酵素学において、'''ジヒドロ葉酸合成酵素'''（{{EnzExplorer|6.3.2.12}}）は、化学反応を触媒する酵素である。")
16:18, 5 April 2024 Fire talk contribs created page Dihydrofolic acid/ja (Created page with "ジヒドロ葉酸合成酵素")
16:17, 5 April 2024 Fire talk contribs created page Translations:Dihydrofolic acid/Page display title/ja (Created page with "ジヒドロ葉酸合成酵素")
16:17, 5 April 2024 Fire talk contribs marked Dihydrofolic acid for translation
16:17, 5 April 2024 Fire talk contribs limited languages for translatable page Dihydrofolic acid to Japanese
16:11, 5 April 2024 Fire talk contribs created page 7,8-dihydrofolic acid (Q21788) (wbeditentity-create:2|en: 7,8-dihydrofolic acid, chemical compound)
16:10, 5 April 2024 Fire talk contribs created page Category:EC 6.3.2 (Created page with "Category:EC 6.3")
16:09, 5 April 2024 Fire talk contribs created page Category:Enzymes of known structure (Created page with "{{Commons}} This category groups enzymes for which at least one atomic-resolution structure has been deposited in the Protein Data Bank. Category:Enzymes {{CatAutoTOC}}")
16:08, 5 April 2024 Fire talk contribs created page Template:Ligases CO CS and CN/ja (Created page with "{{Navbox | name = Ligases CO CS and CN/ja | title = 酵素: CO CS CN ligase/ja (EC 6.1-6.3) | state = {{{state|}}} | listclass = hlist | group1 = 6.1: 炭素-酸素 | list1 = * Aminoacyl tRNA synthetase/ja ** アラニン ** アルギニン ** [[Asparagine—tRNA ligase/ja|アスパラギン]...")
16:03, 5 April 2024 Fire talk contribs created page Template:Ligases CO CS and CN (Created page with "{{Navbox | name = Ligases CO CS and CN | title = Enzymes: CO CS and CN ligases (EC 6.1-6.3) | state = {{{state|}}} | listclass = hlist | group1 = 6.1: Carbon-Oxygen | list1 = * Aminoacyl tRNA synthetase ** Alanine ** Arginine ** Asparagine ** [[Aspartate—tRNA ligase|Aspartate]...")
16:03, 5 April 2024 Fire talk contribs created page Template:PDB link (Created page with "[https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode={{{1}}} {{{1}}}]<noinclude>{{Documentation}} </noinclude>")
16:02, 5 April 2024 Fire talk contribs created page Template:EnzExplorer (Created page with "EC [https://www.enzyme-database.org/query.php?ec={{{1}}} {{{1}}}]<noinclude> {{doc}} Category:Enzymes templates </noinclude>")
16:01, 5 April 2024 Fire talk contribs created page Template:Infobox enzyme (Created page with "{{infobox | above = {{{name|{{{Name|{{PAGENAME}} }}}}}} | bodystyle = {{#switch:{{{align|}}} | left = float:left; clear:left; margin: 0.5em 1em 0.5em 0; | center = float:none; margin:auto | none = float:none; margin: 0.5em 0 0.5em 0; | right | #default = }} | image = {{#invoke:InfoboxImage|InfoboxImage|image={{{image|}}}|size={{{image_size|{{{width|}}}}}}|sizedefault=frameless|alt={{{alt|}}}}} | caption = {{{caption|}}} | headerstyle = background-color: #ddd | lab...")
15:59, 5 April 2024 Fire talk contribs created page Dihydrofolic acid (Created page with "<languages /> <translate> {{Short description|Class of enzymes}} {{infobox enzyme | Name = Dihydrofolate synthase | EC_number = 6.3.2.12 | CAS_number = 37318-62-0 | GO_code = 0008841 | image = 1w7k.jpg | width = 270 | caption = Dihydrofolate synthase monomer, E.Coli }} In enzymology, a '''dihydrofolate synthase''' ({{EnzExplorer|6.3.2.12}}) is an enzyme that catalyzes the chemical reaction :ATP + 7,8-dihydropteroate + L-g...")
15:26, 5 April 2024 Fire talk contribs created page Translations:Folate/46/ja (Created page with "欧州連合の規制では、エネルギー、たんぱく質、脂肪、飽和脂肪、炭水化物、糖質、塩分を表示することが義務づけられている。任意栄養素は、相当量含まれる場合に表示することができる。1日当たりの摂取量の代わりに、基準摂取量（RI）のパーセンテージで表示される。葉酸については、2011年に100%RIが200 μgに設定された。")
15:26, 5 April 2024 Fire talk contribs created page Translations:Folate/45/ja (Created page with "===食品表示=== 米国の食品および栄養補助食品の表示では、1食あたりの摂取量は1日あたりの摂取量（デイリー・バリュー）に対する割合（％DV）で表される。葉酸の表示目的では、1日あたりの価値の100％は400 μgであった。2016年5月27日の更新では、400 μgに据え置かれた。更新された表示規制への準拠は、年間食品売上高がUS$10 百万以...")
15:26, 5 April 2024 Fire talk contribs created page Translations:Folate/44/ja (Created page with "ULを超える量の葉酸の長期摂取を求めた臨床試験のレビューでは、懸念が提起されている。サプリメント由来の過剰摂取は、天然食品由来の摂取よりも懸念され、ビタミンB12との相対的な割合が、有害作用の重要な要因となる可能性がある。一説によると、葉酸を生物学的に活性な形に変換する酵素ジヒドロ葉酸還元酵素...")
15:25, 5 April 2024 Fire talk contribs created page Translations:Folate/43/ja (Created page with "===安全性=== 葉酸は水溶性ビタミンであり、定期的に尿を通して体外に排出されるため、葉酸による毒性のリスクは低い。葉酸の大量摂取に関連する潜在的な問題のひとつは、ビタミンB12欠乏による悪性貧血の診断にマスキング効果をもたらすことであり、ビタミンB12欠乏患者では神経障害を誘発または悪化させる可能性さえ...")
15:24, 5 April 2024 Fire talk contribs created page Translations:Folate/42/ja (Created page with "米国医学研究所は、推定平均必要量（EAR）、推奨食事許容量（RDA）、適正摂取量（AI）、耐容上限摂取量（UL）を定義しており、これらを総称して食事摂取基準（DRI）と呼ぶ。欧州食品安全機関（EFSA）は、RDAの代わりに人口基準摂取量（PRI）、EARの代わりに平均必要量を用いて、これらの情報の集合体...")
15:24, 5 April 2024 Fire talk contribs created page Translations:Folate/41/ja (Created page with "{| class="wikitable" |+米国国立衛生研究所 (U.S.) 栄養勧告 μg DFE/day for RDA, μg 葉酸 for Tolerable upper intake levels/ja (UL) |- ! rowspan="2"|年齢 !colspan="2"|幼児 ! colspan="2"|子供と大人 ! colspan="2"|妊婦 ! colspan="2"|授乳中の女性 |- ! (AI) ! (UL) ! (RDA) ! (UL) ! (RDA) ! (UL) ! (RDA) ! (UL) |- | 0–6ヶ月 | 65 | 設定されていない | style ="text-align: center;" | – | style...")
15:21, 5 April 2024 Fire talk contribs created page Translations:Folate/40/ja (Created page with "==食事推奨量== {{Anchor|Dietary recommendations}} サプリメントで摂取する葉酸と、食品中に含まれるさまざまな形態の葉酸とでは生物学的利用能が異なるため、食事性葉酸等価量（DFE）制度が確立された。1DFEは、食事性葉酸1 μgと定義される。葉酸サプリメントの1 μgは、1.7 μg DFEとカウントされる。この違いの理由は、葉酸を食品に添加したり、食...")
15:21, 5 April 2024 Fire talk contribs created page Translations:Folate/39/ja (Created page with "=== ビタミンB12の活性化=== thumb|葉酸メチオニンサイクルの簡略模式図|360px メチルTHFはビタミンB12をメチル-B12（メチルコバラミン）に変換する。メチル-B12は、ホモシステインメチルトランスフェラーゼによって触媒される反応で、ホモシステインを[...")
15:19, 5 April 2024 Fire talk contribs created page Translations:Folate/38/ja (Created page with "葉酸ホルミルは、GMPとAMPの前駆体であるイノシン一リン酸の生合成における2つのステップに必要である。メチレンテトラヒドロ葉酸は、dUMP（2{{プライム}}-デオキシウリジン-5{{プライム}}-リン酸）からdUMP（2{{prime}}-デオキシチミジン-5{{prime}}-リン酸）の生合成に必要なC1中心を提供する。この変換はthymidylate synthas...")
15:18, 5 April 2024 Fire talk contribs created page Translations:Folate/37/ja (Created page with "=== DNA合成 === {{main/ja|Purine metabolism/ja|Pyrimidine metabolism/ja}} 葉酸誘導体はプリンとピリミジンの生合成に関与する。")