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Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 16:10, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/13/ja (Created page with "{{Stimulants/ja}}{{Vitamins/ja}}")
- 16:10, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/12/ja (Created page with "==外部リンク== *{{Commons category-inline|Pyritinol}}")
- 16:10, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/11/ja (Created page with "== こちらも参照 == * Emoxypine/ja * Pirisudanol/ja * スルブチアミン")
- 16:10, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/10/ja (Created page with "その他のまれな副作用：急性膵炎、光アレルギー性発疹。")
- 16:09, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/9/ja (Created page with "== 副作用 == {{Anchor|Adverse effects}} 副作用には吐き気、頭痛、まれにアレルギー反応（軽度の皮膚反応）などがある。 2004年に行われた6件の症例報告の調査では、ピリチノールと特定の疾患に対するいくつかの薬物を服用している場合、重篤な胆汁うっ滞性肝炎との関連が示唆されている。")
- 16:08, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/8/ja (Created page with " ")
- 16:08, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/7/ja (Created page with "== 利用可能性 == {{Anchor|Availability}} オーストリア、ドイツ、フランス、イタリア、ポルトガル、ギリシャなどヨーロッパ各国で「認知症症候群における慢性的に低下した脳機能の対症療法」および「頭蓋大脳外傷の後遺症の支持療法」として承認されている。フランスでは、臨床試験の結果に基づいて疾患修飾薬としてrheumatoid arthritis/ja|関節リ...")
- 16:07, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/6/ja (Created page with "'''ピリチノール'''（'''Pyritinol'''）は、ピリドキシンジスルフィドまたはピリチオキシン（欧州薬物名Encephabol、Encefabol、Cerbon 6）とも呼ばれ、ビタミンB<sub>6</sub>（ピリドキシン塩酸塩）の半合成水溶性類似体である。1961年にMerck研究所によって、2つのビタミンB<sub>6</sub>化合物（ピリドキシン）をジスルフィド結合させることに...")
- 16:05, 4 April 2024 Fire talk contribs created page Pyritinol/ja (Created page with "{{Infobox drug | Verifiedfields = changed | verifiedrevid = 464377508 | IUPAC_name = 5,5'-[dithiobis(methylene)]bis[4-(hydroxymethyl)-2-methylpyridin-3-ol] | image = Pyritinol.svg")
- 16:05, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/5/ja (Created page with "<!--Chemical data--> | C=16 | H=20 | N=2 | O=4 | S=2 | smiles = Oc1c(c(cnc1C)CSSCc2c(c(O)c(nc2)C)CO)CO | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = SIXLXDIJGIWWFU-UHFFFAOYSA-N }}")
- 16:05, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/4/ja (Created page with "<!--Identifiers--> | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 1098-97-1 | ATC_prefix = N06 | ATC_suffix = BX02 | PubChem = 14190 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 13561 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = AK5Q5FZH2R | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D02160 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 488093")
- 16:05, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/3/ja (Created page with "<!--Pharmacokinetic data--> | bioavailability = | metabolism = | elimination_half-life = 2.5 hours | excretion =")
- 16:05, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/2/ja (Created page with "<!--Clinical data--> | tradename = | pregnancy_category = | legal_status = | routes_of_administration =")
- 16:05, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/1/ja (Created page with "{{Infobox drug | Verifiedfields = changed | verifiedrevid = 464377508 | IUPAC_name = 5,5'-[dithiobis(methylene)]bis[4-(hydroxymethyl)-2-methylpyridin-3-ol] | image = Pyritinol.svg")
- 16:05, 4 April 2024 Fire talk contribs created page Translations:Pyritinol/Page display title/ja (Created page with "ピリチノール")
- 16:05, 4 April 2024 Fire talk contribs marked Pyritinol for translation
- 16:05, 4 April 2024 Fire talk contribs limited languages for translatable page Pyritinol to Japanese
- 16:04, 4 April 2024 Fire talk contribs created page Category:Phenols (Created page with "{{Commons cat|Phenols}} {{Cat main|Phenols}} '''Phenols''' are aromatic compounds with a hydroxyl functional group. The chemistry of the hydroxyl group in this chemical environment is substantially different than those found in alcohols. Category:Hydroxyarenes Category:Benzene derivatives")
- 16:04, 4 April 2024 Fire talk contribs created page Category:Pyridines (Created page with "{{Commons category}} {{Cat main|Pyridine}} Category:Heterocyclic compounds with 1 ring Category:Aromatic nitrogen heterocycles Category:Six-membered rings")
- 16:04, 4 April 2024 Fire talk contribs created page Category:Antioxidants (Created page with "{{Commons category}} {{Cat main|Antioxidant}} Category:Anti-aging substances Category:Biomolecules by physiological function Category:Free radicals")
- 16:02, 4 April 2024 Fire talk contribs created page pyritinol (Q21787) (wbeditentity-create:2|en: pyritinol, chemical compound)
- 16:01, 4 April 2024 Fire talk contribs created page Template:Stimulants/ja (Created page with "{{Navbox | name = Stimulants/ja | title = Stimulant/ja | listclass = hlist | state = {{{state<includeonly>|collapsed</includeonly>}}} | belowstyle = font-style:italic | group1 = Adamantane/ja | list1 = * Adapromine/ja * Amantadine/ja * Bromantane/ja * Memantine/ja * Rimantadine/ja | group2 = アデノシン拮抗薬 | list2 = * 8-Chlorotheophylline/ja * 8-Cyclopentyl-1,3-dimethylxanthine/ja|8-シクロペン...")
- 15:41, 4 April 2024 Fire talk contribs created page Template:Stimulants (Created page with "{{Navbox | name = Stimulants | title = Stimulants | listclass = hlist | state = {{{state<includeonly>|collapsed</includeonly>}}} | belowstyle = font-style:italic | group1 = Adamantanes | list1 = * Adapromine * Amantadine * Bromantane * Memantine * Rimantadine | group2 = Adenosine antagonists | list2 = * 8-Chlorotheophylline * 8-Cyclopentyltheophylline * 8-Phenyltheophylline...")
- 15:41, 4 April 2024 Fire talk contribs created page Pyritinol (Created page with "<languages /> <translate> {{Short description|Chemical compound}} {{Infobox drug | Verifiedfields = changed | verifiedrevid = 464377508 | IUPAC_name = 5,5'-[dithiobis(methylene)]bis[4-(hydroxymethyl)-2-methylpyridin-3-ol] | image = Pyritinol.svg <!--Clinical data--> | tradename = | pregnancy_category = | legal_status = | routes_of_administration = <!--Pharmacokinetic data--> | bioavailability = | metabolism = | elimination_half-life = 2.5 hours | excretion =...")
- 15:22, 4 April 2024 Fire talk contribs created page Template:See/ja (Created page with "<includeonly>{{rellink|1 = {{#if:{{{1|}}}|「{{see/core|{{{1}}}|{{{l1|{{{1}}}}}}}}」 | 「{{error|エラー：記事名が入力されていません}}」 }}{{#if:{{{2|}}}|{{#if:{{{3|}}}|、|および}}「{{see/core|{{{2}}}|{{{l2|{{{2}}}}}}}}」 }}{{#if:{{{3|}}}|{{#if:{{{4|}}}|、|、および}}「{{see/core|{{{3}}}|{{{l3|{{{3}}}}}}}}」 }}{{#if:{{{4|}}}|{{#if:{{{5|}}}|、|、および}}「{{see/core|{{{4}}}|{{{l4|{{{4}}}}}}}}」 }}{{#if:{{{5|}}}|{{#if:{{{6|}}}|、|、...")
- 14:58, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/15/ja (Created page with "Category:Hydroxypyridines Category:B vitamins Category:Dietary supplements")
- 14:58, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/14/ja (Created page with "{{Vitamins/ja}}")
- 14:58, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/13/ja (Created page with "==外部リンク== * Clinical trials testing Pyridoxamine (clinicaltrials.gov): ** [http://clinicaltrials.gov/ct2/results?term=NCT00320060 Effect of Pyridorin in Patients With Diabetic Nephropathy] (NCT00320060) ** [http://clinicaltrials.gov/ct2/results?term=NCT00320021 Effect of Pyridorin in Patients With Diabetic Nephropathy] (NCT00320021) ** [http://clinicaltrials.gov/ct2/results?term=NCT00734253 Safety and Efficacy Study of Pyridorin...")
- 14:58, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/12/ja (Created page with "==こちらも参照== * Pyridoxamine-oxaloacetate transaminase/ja * Pyridoxamine-pyruvate transaminase/ja * Pyridoxamine-phosphate transaminase/ja * List of investigational antipsychotics/ja")
- 14:58, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/11/ja (Created page with "NephroGenex社は、2型糖尿病患者における糖尿病性神経障害の治療薬としてピリドリンのフェーズ2b試験を実施・完了し、フェーズ3試験を開始した。2016年2月24日、NephroGenex社は資金不足のため第3相試験の一時中断を余儀なくされ、最終的には同年末に終了した。その後、同社は2016年4月30日に連邦破産法第11条の適用を申請した。その後まもなく、NephroGenex社...")
- 14:57, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/10/ja (Created page with "2006年、Biostratum社はピリドリンの権利を別の会社NephroGenex社にライセンス供与した。")
- 14:57, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/9/ja (Created page with "2009年1月12日、FDAはピリドキサミンを含む製品は1994年栄養補助食品健康教育法が定義する栄養補助食品の定義から除外されるという裁定を下した。FDAは、1999年7月にBioStratum社が申請し、1999年9月1日に発効したピリドリンの治験薬としての地位は、"新薬として調査承認される前に、この物質が食品または栄養補...")
- 14:56, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/8/ja (Created page with "ピリドリンは初期の臨床試験で成功を収め、224人の患者を対象とした第II相試験で糖尿病性神経障害の進行を遅らせる効果が認められた。しかし2005年、バイオストラタムは資金不足に陥り、第III相試験を開始することができなかった。 Biostratum社の投資家は、Biostratum社にはピリドキサミン自体の特許がなく、ピリドキサミンは栄養補助食品として一般に...")
- 14:54, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/7/ja (Created page with "==FDAの規制活動== ピリドキサミンは、しばしば塩酸塩として栄養補助食品として販売されていた。しかし、米国では、ピリドキサミンは糖尿病性腎症の進行を防ぐためにBiostratum社によって設計された薬物であるPyridorinの有効成分であるため、医薬品として規制されなけ...")
- 14:52, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/6/ja (Created page with "ピリドキサミンはまた、ジカルボニル中間体との反応により、脂質過酸化反応中の高度な脂質酸化最終生成物の生成を阻害する。他の前臨床研究では、ピリドキサミンは糖尿病や腎結石疾患に伴う糖尿病性神経障害や網膜症の治療に有効である可能性がある。 ある研究では...")
- 14:48, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/5/ja (Created page with "糖尿病の動物モデルを用いた様々な前臨床試験から、ピリドキサミンが 腎臓 の 組織学的 状態をアミノグアニジンと同等かそれ以上に改善することが示唆された。これらの結果から、ピリドキサミンは糖尿病性腎症の治療における臨床的有用性が検討されている。")
- 14:44, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/4/ja (Created page with "ピリドキサミンはメイラード反応を阻害し、糖尿病の医学的合併症に関連する高度糖化最終生成物の形成を阻害することができる。ピリドキサミンは、糖化タンパク質から放出されるアマドリ産物の形成における中間体を捕捉するという仮説がある。お...")
- 14:42, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/3/ja (Created page with "==研究== {{Anchor|Research}} ピリドキサミンは多くの遷移金属イオンとかなり弱い錯体を形成することができ、Cu<sup>2+</sup>とFe<sup>3+</sup>を好む。ピリドキサミンの3'-ヒドロキシル基は、効率的なヒドロキシラジカル消去を可能にする。")
- 14:41, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/2/ja (Created page with "'''ピリドキサミン'''（'''Pyridoxamine'''）は、ビタミンB<sub>6</sub>の一形態である。化学的にはピリジン環構造を基本としており、ヒドロキシル、メチル、アミノメチル、ヒドロキシメチル置換基を持つ。ピリドキシンとは4位の置換基で異なる。その環の...")
- 14:39, 4 April 2024 Fire talk contribs created page Pyridoxamine/ja (Created page with "{{Chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464377112 | ImageFile_Ref = {{chemboximage|correct|??}} | ImageFile = Pyridoxamin.svg | ImageSize = 120px | PIN = 4-(Aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol | OtherNames = |Section1={{Chembox Identifiers | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = C00534 | InChI = 1/C8H12N2O2/c1-5-8(12)7(2-9)6(4-11)3-10-5/h3,11-12H,2,4,9H2,1H3 | InChIKey = NHZMQXZHNVQTQA-UHFFFAOYAS | StdInCh...") Tags: Mobile edit Mobile web edit
- 14:39, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/1/ja (Created page with "{{Chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464377112 | ImageFile_Ref = {{chemboximage|correct|??}} | ImageFile = Pyridoxamin.svg | ImageSize = 120px | PIN = 4-(Aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol | OtherNames = |Section1={{Chembox Identifiers | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = C00534 | InChI = 1/C8H12N2O2/c1-5-8(12)7(2-9)6(4-11)3-10-5/h3,11-12H,2,4,9H2,1H3 | InChIKey = NHZMQXZHNVQTQA-UHFFFAOYAS | StdInCh...")
- 14:38, 4 April 2024 Fire talk contribs created page Translations:Pyridoxamine/Page display title/ja (Created page with "ピリドキサミン")
- 14:38, 4 April 2024 Fire talk contribs marked Pyridoxamine for translation
- 14:38, 4 April 2024 Fire talk contribs limited languages for translatable page Pyridoxamine to Japanese
- 14:37, 4 April 2024 Fire talk contribs created page Preferred IUPAC name (Redirected page to en:Preferred IUPAC name) Tag: New redirect
- 09:35, 4 April 2024 Fire talk contribs created page pyridoxamine transmembrane transport (Q21786) (wbeditentity-create:2|en: pyridoxamine transmembrane transport, The directed movement of pyridoxamine across a membrane.)
- 09:34, 4 April 2024 Fire talk contribs created page pyridoxamine transmembrane transporter activity (Q21785) (wbeditentity-create:2|en: pyridoxamine transmembrane transporter activity, Enables the directed movement of pyridoxamine into, out of or within a cell, or between cells. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collec)
- 09:31, 4 April 2024 Fire talk contribs created page pyridoxamine transport (Q21784) (wbeditentity-create:2|en: pyridoxamine transport, The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyr)
- 09:30, 4 April 2024 Fire talk contribs created page pyridoxamine binding (Q21783) (wbeditentity-create:2|en: pyridoxamine binding, Interacting selectively and non-covalently with pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.)
- 09:29, 4 April 2024 Fire talk contribs created page pyridoxamine (Q21782) (wbeditentity-create:2|en: pyridoxamine, chemical compound)