Main public logs

Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

• 20:35, 12 March 2024 Fire talk contribs created page Template:Italics correction/calc (Created page with "{{#switch:{{{1}}} |d|i|j|k|ℓ|r|t|v|w|x|y|z|C|D|E|F|G|H|I|J|K|M|N|P|U|V|W|X|Y|Z|γ|δ|ζ|ξ|ϖ|π|σ|τ|Ε|Ζ|Η|Ι|Κ|Μ|Ν|Ξ|Π|Ρ|Σ|Υ|ϒ|Χ|Ψ=0.05em |c|g|s|u|B|G|O|Q|R|S|α|β|ε|ϵ|ϑ|θ|κ|μ|ν|ς|υ|χ|ψ|ω|Β|Θ|Ο|Ω=0.05em |a|b|∂|e|h|m|n|o|p|q|A|L|η|ι|λ|ο|ϱ|ρ|φ|ϕ|Α|Δ|Λ|Φ=0em |f|l|T|Γ|Τ=0.15em |0.1em }}<noinclude><!-- Latin lower-case: abc∂defghijlℓmnopqrstuvwxyz Latin upper-case: ABCDEFGHIJLNOPQRSTUVWXYZ Greek lower-case: αβγδεϵ...")
• 20:34, 12 March 2024 Fire talk contribs created page Category:Sulfonylureas (Created page with "{{Cat main|Sulfonylureas}} {{Commons cat|Sulfonylureas}} Category:Anti-diabetic drugs Category:Sulfonamides Category:Ureas")
• 20:33, 12 March 2024 Fire talk contribs created page Category:Disulfiram-like drugs (Created page with "{{Commonscat|Disulfiram-like drugs}} {{Cat main|Disulfiram-like drug}} Disulfiram-like drugs that produce sensitivity to the toxic effects of alcohol (drug). Mostly acetaldehyde dehydrogenase inhibitors. Category:Alcohol Category:Alcohol abuse Category:Enzyme inhibitors")
• 20:32, 12 March 2024 Fire talk contribs created page sulfonylurea (Q21470) (wbeditentity-create:2|en: sulfonylurea, class of organic compounds)
• 20:31, 12 March 2024 Fire talk contribs created page Template:Prime (Created page with "{{{1|}}}<span class="nowrap" style="padding-left:{{{sp|{{Italics correction/calc|{{{2|{{#invoke:String|pos|{{{1|f}}}|-1}}}}}}}}}};">{{{c|′}}}</span><noinclude> {{documentation}} </noinclude>")
• 20:30, 12 March 2024 Fire talk contribs created page Sulfonylurea (Created page with "{{Short description|Class of organic compounds used in medicine and agriculture}} thumb|right|General structural formula of a sulfonylurea. The functional group consists of a sulfonyl group and a N-substituted ureylene group '''Sulfonylureas''' or '''sulphonylureas''' are a class of organic compounds used in medicine and agriculture. The functional group consists of a sulfonyl group (-S(=O)₂) with i...")
• 20:24, 12 March 2024 Fire talk contribs created page Hypoglycemic agent/ja (Redirected page to 糖尿病治療薬) Tag: New redirect
• 20:23, 12 March 2024 Fire talk contribs created page Hypoglycemic agent (Redirected page to Diabetes medication) Tag: New redirect
• 20:21, 12 March 2024 Fire talk contribs created page Translations:Sitagliptin/7/ja (Created page with "<!-- Definition and medical uses --> '''シタグリプチン'''（'''sitagliptin''', ブランド名'''ジャヌビア'''他）は、2型糖尿病の治療に用いられる抗糖尿病薬である。イギリスではメトホルミンやスルホニルウレアよりも優先度が低いとされている。口から服用する。また、fixed-dos...")
• 20:19, 12 March 2024 Fire talk contribs created page Translations:Sitagliptin/6/ja (Created page with "<!-- Chemical and physical data --> | IUPAC_name = (''R'')-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-''a'']pyrazin-7(8''H'')-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine | C=16 | H=15 | F=6 | N=5 | O=1 | SMILES = Fc1cc(c(F)cc1F)C[C@@H](N)CC(=O)N3Cc2nnc(n2CC3)C(F)(F)F | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/...")
• 20:19, 12 March 2024 Fire talk contribs created page Translations:Sitagliptin/5/ja (Created page with "<!-- Identifiers --> | index2_label = as salt | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 486460-32-6 | CAS_supplemental = | PubChem = 4369359 | IUPHAR_ligand = 6286 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB01261 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 3571948 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = QFP0P1DV7Z | KEGG_Ref = | KEGG = D08516 | KEGG2_Ref = | KEGG2 = D06645 | ChEBI_Ref = {{ebic...")
• 20:18, 12 March 2024 Fire talk contribs created page Translations:Sitagliptin/4/ja (Created page with "<!-- Pharmacokinetic data --> | bioavailability = 87% | protein_bound = 38% | metabolism = 肝臓 (CYP3A4- と CYP2C8-介在) | metabolites = | onset = | elimination_half-life = 8 to 14 h | duration_of_action = | excretion = Kidney/ja (80%)")
• 20:18, 12 March 2024 Fire talk contribs created page Sitagliptin/ja (Created page with "<!-- Legal status --> | legal_AU = S4 | legal_AU_comment = | legal_BR = <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F --> | legal_BR_comment = | legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_CA_comment = | legal_DE = <!-- Anlage I, II, III or Unscheduled --> | legal_DE_comment = | legal_NZ = <!-- Class A, B, C --> | legal_NZ_comment = | legal_UK = POM | legal_UK_comment = | legal_US = Rx-only | legal_US_comment...") Tags: Mobile edit Mobile web edit
• 20:18, 12 March 2024 Fire talk contribs created page Translations:Sitagliptin/3/ja (Created page with "<!-- Legal status --> | legal_AU = S4 | legal_AU_comment = | legal_BR = <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F --> | legal_BR_comment = | legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_CA_comment = | legal_DE = <!-- Anlage I, II, III or Unscheduled --> | legal_DE_comment = | legal_NZ = <!-- Class A, B, C --> | legal_NZ_comment = | legal_UK = POM | legal_UK_comment = | legal_US = Rx-only | legal_US_comment...")
• 20:17, 12 March 2024 Fire talk contribs created page Translations:Sitagliptin/2/ja (Created page with "<!-- Clinical data --> | pronounce = {{IPAc-en|audio=En-us-Sitagliptin.ogg|s|ɪ|t|ə|ˈ|g|l|ɪ|p|t|ɪ|n}} | tradename = Januvia, Zituvio, others | Drugs.com = {{drugs.com|monograph|sitagliptin}} | MedlinePlus = a606023 | DailyMedID = Sitagliptin | pregnancy_AU = B3 | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = 経口 | class = | ATC_prefix = A10 | ATC_suffix = BH01 | ATC_supplemental =")
• 20:17, 12 March 2024 Fire talk contribs created page Translations:Sitagliptin/1/ja (Created page with "{{Infobox drug | Watchedfields = changed | verifiedrevid = 464392221 | image = Sitagliptin.svg | width = 254 | alt = | image2 = Sitagliptin 3D.png | alt2 = | caption =")
• 20:17, 12 March 2024 Fire talk contribs created page Translations:Sitagliptin/Page display title/ja (Created page with "シタグリプチン")
• 20:17, 12 March 2024 Fire talk contribs marked Sitagliptin for translation
• 20:17, 12 March 2024 Fire talk contribs limited languages for translatable page Sitagliptin to Japanese
• 20:15, 12 March 2024 Fire talk contribs created page Category:Triazoles (Created page with "{{Cat main|Triazole}} {{Commons cat|Triazoles}} Category:Azoles Category:Five-membered rings")
• 20:15, 12 March 2024 Fire talk contribs created page Category:Drugs developed by Merck & Co. (Created page with "{{Commonscat}} {{Cat main|Merck & Co.}} Category:Brands by company Category:Drug brand names Category:Health care brands Brands {{CatAutoTOC}}")
• 20:15, 12 March 2024 Fire talk contribs created page Category:Trifluoromethyl compounds (Created page with "{{Commons category|Trifluoromethyl compounds}} {{Cat main|Trifluoromethyl}} {{CatAutoTOC}} Category:Organofluorides")
• 20:14, 12 March 2024 Fire talk contribs created page Category:Drugboxes which contain changes to watched fields (Created page with "{{polluted category}} {{hidden category}} {{Chemical data validation}} This category contains pages which have been tagged by User:CheMoBot as having 'watched' fields which have been changed since the page has been verified (see Wikipedia:WikiProject Chemicals/Chembox validation). V Chemical data validation {{CatAutoTOC}}")
• 20:11, 12 March 2024 Fire talk contribs created page sitagliptin (Q21469) (wbeditentity-create:2|en: sitagliptin, chemical compound)
• 20:10, 12 March 2024 Fire talk contribs created page Template:Merck&Co/ja (Created page with "{{Navbox |name = Merck&Co/ja |title = Merck & Co., Inc. |state = {{{state|autocollapse}}} |bodyclass = hlist |group1 = 子会社 |list1 = * Acceleron Pharma * Cubist Pharmaceuticals * H. K. Mulford Company * Schering-Plough * Viralytics |group2 = 製品 |list2 = * アレンドロネート * Aprepitant/ja * Ertapenem/ja * Ezetimibe/ja * Ezetimibe/simvastatin/ja * Finasteride/ja * Fosaprepit...")
• 20:06, 12 March 2024 Fire talk contribs created page Template:Merck&Co (Created page with "{{Navbox |name = Merck&Co |title = Merck & Co., Inc. |state = {{{state|autocollapse}}} |bodyclass = hlist |group1 = Corporate directors |list1 = * Richard Clark * Johnnetta Cole * William Harrison * William Kelley * Rochelle Lazarus * Thomas Shenk * Anne Tatlock * Samuel Thier * Wendell Weeks * Peter Wendell |group2 = Subsidiaries |list2...")
• 20:05, 12 March 2024 Fire talk contribs created page Sitagliptin (Created page with "{{Short description|Diabetes medication}} {{Infobox drug | Watchedfields = changed | verifiedrevid = 464392221 | image = Sitagliptin.svg | width = 254 | alt = | image2 = Sitagliptin 3D.png | alt2 = | caption = <!-- Clinical data --> | pronounce = {{IPAc-en|audio=En-us-Sitagliptin.ogg|s|ɪ|t|ə|ˈ|g|l|ɪ|p|t|ɪ|n}} | tradename = Januvia, Zituvio, others | Drugs.com = {{drugs.com|monograph|sitagliptin}} | MedlinePlus = a606023 | DailyMedID = Sitagliptin | pregnancy_AU...")
• 19:59, 12 March 2024 Fire talk contribs created page Oral hypoglycemic/ja (Redirected page to 糖尿病治療薬) Tag: New redirect
• 19:59, 12 March 2024 Fire talk contribs created page Oral hypoglycemic (Redirected page to Diabetes medication) Tag: New redirect
• 19:57, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/20/ja (Created page with "{{DEFAULTSORT:Dipeptidyl Peptidase-4 Inhibitor}} ")
• 19:57, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/19/ja (Created page with "{{Oral hypoglycemics/ja}} {{Enzyme inhibition/ja}}")
• 19:57, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/18/ja (Created page with "== こちらも参照 == * Development of dipeptidyl peptidase-4 inhibitors/ja")
• 19:57, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/17/ja (Created page with "==併用薬物== {{Anchor|Combination drugs}} DPP-4阻害薬の中には、メトホルミンと併用することで相乗効果を発揮し、グルカゴン様ペプチド1（GLP-1）のレベルを上昇させ、肝の|グルコース産生を低下させる。")
• 19:56, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/16/ja (Created page with "2014年のメタアナリシスでは、DPP-4阻害薬で治療された患者における膵臓がんリスク増加のエビデンスは認められなかったが、入手可能なデータ量が少ないため、可能性のあるリスクを完全に除外することはできなかった。")
• 19:56, 12 March 2024 Fire talk contribs created page Translations:Biguanide/16/ja (Created page with "====副作用と毒性==== 最も一般的な副作用は下痢と消化不良であり、患者の最大30％に発現する。 最も重要で重篤な副作用は乳酸アシドーシスであるため、メトホルミンは進行した慢性腎臓病では禁忌である。メトホルミンを開始する前に腎機能を評価すべきである。フェンホルミンとブホルミンはメト...")
• 19:55, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/15/ja (Created page with "===癌=== DPP-4阻害薬シタグリプチンを投与されたラットおよび臓器提供者の膵臓に前癌性変化がみられたという報告を受けて、米国FDAと欧州医薬品庁はそれぞれ、DPP-4阻害薬と膵癌との関連の可能性に関するすべての臨床および前臨床データの独立したレビューを行った。ニューイングランド・ジャーナル・オブ・メディシン誌への共同書簡の中で、両機...")
• 19:54, 12 March 2024 Fire talk contribs created page Translations:Biguanide/15/ja (Created page with "ビグアナイドは銅と相互作用することが示されており、特にミトコンドリアでは、2+酸化状態の銅（Cu(II)）をキレート化することによって、細胞の代謝を阻害する。")
• 19:53, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/14/ja (Created page with "2020年のコクラン系統的レビューでは、2型糖尿病の治療においてメトホルミン単剤療法とジペプチジルペプチダーゼ-4阻害薬を比較した場合、全死亡、重篤な有害事象、心血管死亡、非致死的心筋梗塞、非致死的脳卒中、または末期腎疾患の減少を示す十分なエビデンスは認められなかっ...")
• 19:52, 12 March 2024 Fire talk contribs created page Translations:Biguanide/14/ja (Created page with "しかし、高インスリン血症では、ビグアナイド薬は血漿中のインスリンの空腹時レベルを低下させる。 ビグアナイド薬の治療的用途は、肝臓での糖新生を減少させ、その結果、血液中のグルコース濃度を低下させる傾向からきている。 ビグアナイドはまた、体内の細胞が血流中にすでに存在するグルコースを吸収しやすくする傾向があ...")
• 19:52, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/13/ja (Created page with "2018年の観察研究では、炎症性腸疾患（具体的には潰瘍性大腸炎）の発症リスクの上昇が示唆され、3～4年の使用でピークに達し、4年以上の使用で減少した。")
• 19:52, 12 March 2024 Fire talk contribs created page Translations:Biguanide/13/ja (Created page with "主にII型糖尿病に用いられるメトホルミンは、生体内でインスリン感受性を高め、血漿グルコース濃度の低下、グルコース取り込みの増加、糖新生の減少をもたらすと考えられている。")
• 19:51, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/12/ja (Created page with "2018年のメタ解析によると、DPP-4阻害薬の使用は、プラセボまたは無治療と比較して、急性膵炎の発症リスクを58％増加させることが示された。")
• 19:51, 12 March 2024 Fire talk contribs created page Translations:Biguanide/12/ja (Created page with "ビグアナイド薬は、スルホニル尿素やメグリチニドなどの他の血糖降下薬とは異なり、インスリンの分泌に影響を与えない。 したがって、ビグアナイド薬は2型糖尿病患者に有効であり、インスリン療法と併用すれば1型糖尿病にも有効である。")
• 19:50, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/11/ja (Created page with "2014年のレビューで、サキサグリプチンおよびアログリプチンによる心不全のリスク増加が発見され、FDAは2016年に関連薬物のラベルに警告を追加した。")
• 19:50, 12 March 2024 Fire talk contribs created page Translations:Biguanide/11/ja (Created page with "====作用機序=== ビグアナイド薬の作用機序は完全には解明されておらず、メトホルミンについては多くの機序が提唱されている。")
• 19:49, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/10/ja (Created page with "米国食品医薬品局（FDA）は、2型糖尿病治療薬であるシタグリプチン、サキサグリプチン、リナグリプチン、アログリプチンが、関節痛を引き起こし、重篤な障害を引き起こす可能性があると警告している。FDAは、ジペプチジルペプチダーゼ-4（DPP-4）阻害薬と呼ばれるこのクラスの薬物のラベルに...")
• 19:48, 12 March 2024 Fire talk contribs created page Translations:Biguanide/10/ja (Created page with "====歴史==== {{details/ja|metformin/ja#History}} ''ガレガ・オフィシナリス''（フランスのライラック）は、何世紀にもわたって糖尿病治療に用いられてきた。1920年代、'''ガレガ'''の抽出物からグアニジン化合物が発見された。動物実験では、これらの化合物が血糖値を下げることが示された。毒性の低い誘導体であるsynthalin/ja|シ...")
• 19:47, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/9/ja (Created page with "副作用には鼻咽頭炎、頭痛、吐き気、心不全、過敏症、皮膚反応などがある。")
• 19:44, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/8/ja (Created page with "==副作用== {{Anchor|Adverse effects}} すでにスルホニルウレアを服用している場合、DPP-4薬物クラスの薬を服用すると低血糖のリスクが高まる。")
• 19:43, 12 March 2024 Fire talk contribs created page Translations:Biguanide/17/ja (Created page with "===抗マラリア薬=== 第二次世界大戦中、フランク・ローズが率いるイギリスのチームが、いくつかのビグアナイドが抗マラリア薬として有用であることを発見した（詳細はそちらを参照）。ずっと後になって、それらは活性のあるジヒドロトリアジン誘導体に代謝されるプロドラッグであることが...")