Main public logs

Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

• 12:59, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/11/ja (Created page with "===多嚢胞性卵巣症候群=== GLP-1作動薬は、単独またはメトホルミンとの併用で、多嚢胞性卵巣症候群の治療薬として推奨されている。併用療法は、体重、インスリン感受性、アンドロゲン亢進症、および月経周期不順の改善においてより高い有効性を示している。この使用法は適応外...")
• 12:56, 6 February 2024 Fire talk contribs created page thiamine pyrophosphate binding (Q20556) (wbeditentity-create:2|en: thiamine pyrophosphate binding, Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.)
• 12:55, 6 February 2024 Fire talk contribs created page Thiamin Diphosphate (Q20555) (wbeditentity-create:2|en: Thiamin Diphosphate, chemical compound)
• 12:52, 6 February 2024 Fire talk contribs created page thiamine diphosphate metabolic process (Q20554) (wbeditentity-create:2|en: thiamine diphosphate metabolic process, The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.)
• 12:51, 6 February 2024 Fire talk contribs created page thiamine diphosphate biosynthetic process (Q20553) (wbeditentity-create:2|en: thiamine diphosphate biosynthetic process, The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.)
• 12:49, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/10/ja (Created page with "===非アルコール性脂肪性肝疾患=== GLP-1作動薬は、非アルコール性脂肪性肝疾患（NAFLD）の治療薬として研究されている。 2023年のシステマティックレビューによれば、GLP-1作動薬は現在使用されているピオグリタゾンやビタミンEと少なくとも同等の効果があり、脂肪症、バルーン壊死、小葉の炎症...")
• 12:45, 6 February 2024 Fire talk contribs created page thiamin-triphosphatase activity (Q20552) (wbeditentity-create:2|en: thiamin-triphosphatase activity, Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate.)
• 12:44, 6 February 2024 Fire talk contribs created page thiamine(1+) triphosphate(4-) (Q20551) (wbeditentity-create:2|en: thiamine(1+) triphosphate(4-), chemical compound)
• 12:42, 6 February 2024 Fire talk contribs created page thiamine-diphosphate kinase activity (Q20550) (wbeditentity-create:2|en: thiamine-diphosphate kinase activity, Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate.)
• 12:39, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/9/ja (Created page with "===肥満症=== GLP-1作動薬は、BMIが30を超えるか、またはBMIが27を超え、少なくとも1つの体重関連合併症を有する患者において、生活習慣介入（カロリー制限および運動）の上乗せ療法として推奨されている。セマグルチドなどの一部のGLP-1作動薬は、他の減量薬よりも効果が高いが、それでも体重減少を引き起こすという点ではbariatric surg...")
• 12:36, 6 February 2024 Fire talk contribs created page thiamine-diphosphatase activity (Q20549) (wbeditentity-create:2|en: thiamine-diphosphatase activity, Catalysis of the reaction: TDP + H2O = TMP + phosphate.)
• 12:33, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/8/ja (Created page with "===心血管疾患=== GLP-1作動薬は、肥満の治療に用いると心臓保護作用を示す。")
• 12:32, 6 February 2024 Fire talk contribs created page acid phosphatase activity (Q20548) (wbeditentity-create:2|en: acid phosphatase activity, Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.)
• 12:30, 6 February 2024 Fire talk contribs created page thiamine phosphate phosphatase activity (Q20547) (wbeditentity-create:2|en: thiamine phosphate phosphatase activity, Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate.)
• 12:28, 6 February 2024 Fire talk contribs created page thiamine kinase activity (Q20546) (wbeditentity-create:2|en: thiamine kinase activity, Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate.)
• 12:22, 6 February 2024 Fire talk contribs created page 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity (Q20545) (wbeditentity-create:2|en: 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity, Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H(+).)
• 12:17, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/7/ja (Created page with "GLP-1作動薬は1型糖尿病に対してFDAの承認を受けていないが、1型糖尿病患者の体重とグルコースコントロールを改善するために、インスリンに加えて適応外で使用することができる。")
• 12:16, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/6/ja (Created page with "2021年のメタアナリシスでは、2型糖尿病の治療にGLP-1アナログを使用した場合、全死因死亡率が12％減少し、心血管および腎アウトカムの有意な改善も認められた。13の心血管アウトカム試験を含むメタアナリシスでは、SGLT-2阻害薬は、特に推算糸球体濾過量（eGFR）が60 mL/min未満の被験者において、3点...")
• 12:15, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/5/ja (Created page with "==適応症== {{Anchor|Indications}} ===2型糖尿病=== GLP-1作動薬は、当初2型糖尿病のために開発された。2022年の米国糖尿病学会（ADA）の糖尿病診療基準では、動脈硬化性心血管系疾患または心不全のリスクが高い、またはある患者における2型糖尿病のファーストライン[...")
• 12:11, 6 February 2024 Fire talk contribs created page 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium (Q20544) (wbeditentity-create:2|en: 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium, chemical compound)
• 12:10, 6 February 2024 Fire talk contribs created page thiamine pyridinylase activity (Q20543) (wbeditentity-create:2|en: thiamine pyridinylase activity, Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine.)
• 12:07, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/4/ja (Created page with "==作用機序== {{Anchor|Mechanism of action}} GLP-1作動薬は、GLP-1受容体を活性化することによって作用する。GLP-1作動薬は、胃排出を遅らせ、グルカゴンの放出を阻害し、インスリン産生を刺激するため、2型糖尿病の高血糖を軽減する。それらは食物摂取を減少させ、それによって体重も...")
• 12:02, 6 February 2024 Fire talk contribs created page 4-methyl-5-(2-phosphonatooxyethyl)thiazole(2-) (Q20542) (wbeditentity-create:2|en: 4-methyl-5-(2-phosphonatooxyethyl)thiazole(2-), chemical compound)
• 12:00, 6 February 2024 Fire talk contribs created page hydroxyethylthiazole kinase activity (Q20541) (wbeditentity-create:2|en: hydroxyethylthiazole kinase activity, Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+).)
• 11:59, 6 February 2024 Fire talk contribs created page 4-methyl-5-thiazoleethanol (Q20540) (wbeditentity-create:2|en: 4-methyl-5-thiazoleethanol, chemical compound)
• 11:56, 6 February 2024 Fire talk contribs created page thiaminase activity (Q20539) (wbeditentity-create:2|en: thiaminase activity, Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+).)
• 11:55, 6 February 2024 Fire talk contribs created page toxopyrimidine (Q20538) (wbeditentity-create:2|en: toxopyrimidine, chemical compound)
• 11:54, 6 February 2024 Fire talk contribs created page hydroxymethylpyrimidine kinase activity (Q20537) (wbeditentity-create:2|en: hydroxymethylpyrimidine kinase activity, Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+).)
• 11:53, 6 February 2024 Fire talk contribs created page 4-amino-2-methyl-5-phosphonatooxymethylpyrimidine(2-) (Q20536) (wbeditentity-create:2|en: 4-amino-2-methyl-5-phosphonatooxymethylpyrimidine(2-), chemical compound)
• 11:51, 6 February 2024 Fire talk contribs created page phosphomethylpyrimidine kinase activity (Q20535) (wbeditentity-create:2|en: phosphomethylpyrimidine kinase activity, Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine.)
• 11:50, 6 February 2024 Fire talk contribs created page 4-amino-2-methyl-5-diphosphonatooxymethylpyrimidine(3-) (Q20534) (wbeditentity-create:2|en: 4-amino-2-methyl-5-diphosphonatooxymethylpyrimidine(3-), chemical compound)
• 11:48, 6 February 2024 Fire talk contribs created page thiamine-phosphate diphosphorylase activity (Q20533) (wbeditentity-create:2|en: thiamine-phosphate diphosphorylase activity, Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate.)
• 11:47, 6 February 2024 Fire talk contribs created page thiamine(1+) monophosphate(2-) (Q20532) (wbeditentity-create:2|en: thiamine(1+) monophosphate(2-), chemical compound)
• 11:46, 6 February 2024 Fire talk contribs created page thiamine-phosphate kinase activity (Q20531) (wbeditentity-create:2|en: thiamine-phosphate kinase activity, Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate.)
• 23:05, 5 February 2024 Fire talk contribs created page thiamine(1+) diphosphate(3-) (Q20530) (wbeditentity-create:2|en: thiamine(1+) diphosphate(3-), chemical compound)
• 23:02, 5 February 2024 Fire talk contribs created page thiamine diphosphokinase activity (Q20529) (wbeditentity-create:2|en: thiamine diphosphokinase activity, Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.)
• 23:00, 5 February 2024 Fire talk contribs created page thiamine salvage (Q20528) (wbeditentity-create:2|en: thiamine salvage, A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.)
• 22:58, 5 February 2024 Fire talk contribs created page cellular response to vitamin B1 (Q20527) (wbeditentity-create:2|en: cellular response to vitamin B1, Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.)
• 22:57, 5 February 2024 Fire talk contribs created page response to vitamin B1 (Q20526) (wbeditentity-create:2|en: response to vitamin B1, Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.)
• 22:53, 5 February 2024 Fire talk contribs created page thiamine-containing compound catabolic process (Q20525) (wbeditentity-create:2|en: thiamine-containing compound catabolic process, The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.)
• 22:52, 5 February 2024 Fire talk contribs created page thiamine catabolic process (Q20524) (wbeditentity-create:2|en: thiamine catabolic process, The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.)
• 22:49, 5 February 2024 Fire talk contribs created page thiamine binding (Q20523) (wbeditentity-create:2|en: thiamine binding, Interacting selectively and non-covalently with thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.)
• 22:47, 5 February 2024 Fire talk contribs created page thiamine(1+) diphosphate (Q20522) (wbeditentity-create:2|en: thiamine(1+) diphosphate, chemical compound)
• 22:45, 5 February 2024 Fire talk contribs created page monophosphothiamine (Q20521) (wbeditentity-create:2|en: monophosphothiamine, chemical compound)
• 22:44, 5 February 2024 Fire talk contribs created page thiamine hydrochloride dihydrate (Q20520) (wbeditentity-create:2|en: thiamine hydrochloride dihydrate, chemical compound)
• 22:42, 5 February 2024 Fire talk contribs created page thiamine(1+) chloride (Q20519) (wbeditentity-create:2|en: thiamine(1+) chloride, chemical compound)
• 22:40, 5 February 2024 Fire talk contribs created page thiazole alkaloid (Q20518) (wbeditentity-create:2|en: thiazole alkaloid, class of chemical compounds)
• 22:37, 5 February 2024 Fire talk contribs created page thiamine(1+) ion (Q20517) (wbeditentity-create:2|en: thiamine(1+) ion, chemical compound)
• 22:33, 5 February 2024 Fire talk contribs created page thiamine transport (Q20516) (wbeditentity-create:2|en: thiamine transport, The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.)
• 22:32, 5 February 2024 Fire talk contribs created page thiamine transmembrane transport (Q20515) (wbeditentity-create:2|en: thiamine transmembrane transport, The directed movement of thiamine across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especial)