Pyridoxamine/ja: Difference between revisions

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'''Pyridoxamine''' ~~is one form of~~ [[vitamin B6|~~vitamin B~~<sub>6</sub>]]~~. Chemically it is based on a~~ [[pyridine]] ~~ring structure, with~~ [[hydroxyl]], [[methyl]], [[aminomethyl]]~~, and~~ [[hydroxymethyl]] [[~~substituent~~]]~~s. It differs from~~ [[pyridoxine]] ~~by the substituent at the 4-position. The hydroxyl at position 3 and aminomethyl group at position 4 of its ring endow pyridoxamine with a variety of chemical properties, including the~~ [[~~Scavenger~~ (chemistry)|~~scavenging~~]] of [[~~free radical~~]] ~~species and carbonyl species formed in sugar and lipid degradation and~~ [[chelation~~]] of metal ions that catalyze [[Amadori rearrangement~~|~~Amadori reactions~~]].

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+'''ピリドキサミン'''（'''Pyridoxamine'''）は、[[vitamin B6/ja|ビタミンB<sub>6</sub>]]の一形態である。化学的には[[pyridine/ja|ピリジン]]環構造を基本としており、[[hydroxyl/ja|ヒドロキシル]]、[[methyl/ja|メチル]]、[[aminomethyl/ja|アミノメチル]]、[[hydroxymethyl/ja|ヒドロキシメチル]][[subtituent/ja|置換基]]を持つ。[[pyridoxine/ja|ピリドキシン]]とは4位の置換基で異なる。その環の3位のヒドロキシルと4位のアミノメチル基は、ピリドキサミンに、糖や脂質の分解で形成される[[free radical/ja|フリーラジカル]]種やカルボニル種の[[scavenger (chemistry)/ja|スカベンジャー]]作用や、[[amadori rearrangement/ja|アマドリ反応]]を触媒する金属イオンの[[chelation/ja|キレート化]]作用など、様々な化学的性質を与える。
-'''Pyridoxamine''' is one form of [[vitamin B6|vitamin B<sub>6</sub>]]. Chemically it is based on a [[pyridine]] ring structure, with [[hydroxyl]], [[methyl]], [[aminomethyl]], and [[hydroxymethyl]] [[substituent]]s. It differs from [[pyridoxine]] by the substituent at the 4-position. The hydroxyl at position 3 and aminomethyl group at position 4 of its ring endow pyridoxamine with a variety of chemical properties, including the [[Scavenger (chemistry)|scavenging]] of [[free radical]] species and carbonyl species formed in sugar and lipid degradation and [[chelation]] of metal ions that catalyze [[Amadori rearrangement|Amadori reactions]].
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