Prohormone: Difference between revisions
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{{Short description|Precursor of a hormone}} | {{Short description|Precursor of a hormone}} | ||
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A '''prohormone''' is a committed [[Precursor (chemistry)|precursor]] of a [[hormone]] consisting of [[peptide hormone]]s synthesized together that has a minimal hormonal effect by itself because of its expression-suppressing structure, often created by protein folding and binding additional peptide chains to certain ends, that makes hormone receptor binding sites located on its peptide hormone chain segments inaccessible. Prohormones can travel the [[blood stream]] as a hormone in an inactivated form, ready to be activated later in the cell by [[post-translational modification]]. | A '''prohormone''' is a committed [[Precursor (chemistry)|precursor]] of a [[hormone]] consisting of [[peptide hormone]]s synthesized together that has a minimal hormonal effect by itself because of its expression-suppressing structure, often created by protein folding and binding additional peptide chains to certain ends, that makes hormone receptor binding sites located on its peptide hormone chain segments inaccessible. Prohormones can travel the [[blood stream]] as a hormone in an inactivated form, ready to be activated later in the cell by [[post-translational modification]]. | ||