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Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 15:12, 15 February 2024 Fire talk contribs created page Translations:Diabetes/29/ja (Created page with "インスリンは、膵臓のランゲルハンス島にあるβ細胞（ベータ細胞）によって、血中グルコースレベルの上昇に反応して血液中に放出される。インスリンは、燃料として使用するため、他の必要な分子に変換するため、または貯蔵するために血液からグルコースを吸収するために、身体の細胞の約3分の2によって使用される。グルコ...")
- 15:10, 15 February 2024 Fire talk contribs created page ribose 1,5-bisphosphate phosphokinase activity (Q21027) (wbeditentity-create:2|en: ribose 1,5-bisphosphate phosphokinase activity, Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+).)
- 15:09, 15 February 2024 Fire talk contribs created page Translations:Diabetes/28/ja (Created page with "すなわち、食物の腸管吸収、肝臓に貯蔵されているグルコースの貯蔵形態であるグリコーゲンの分解（グリコーゲン分解）、および体内の非炭水化物基質からのグルコースの生成である糖新生である。インスリンは体内のグルコースレベルの調節に重要な役割を果たしている。インスリンはグリコーゲンの分...")
- 15:06, 15 February 2024 Fire talk contribs created page orotate phosphoribosyltransferase activity (Q21026) (wbeditentity-create:2|en: orotate phosphoribosyltransferase activity, Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.)
- 10:55, 15 February 2024 Fire talk contribs created page Translations:Diabetes/27/ja (Created page with "==病態生理学== {{Anchor|Pathophysiology}} thumb|upright=1.4|[[Blood sugar level|血糖（赤）と糖低下ホルモンインスリン（青）のヒトにおける1日3食の間の変動。砂糖リッチな食事とデンプンリッチな食事の効果の1つが強調されている。]] File:Glucose-insulin-release.svg|thumb|upright=1.4|正常な膵臓[[beta cell/ja|β...")
- 10:51, 15 February 2024 Fire talk contribs created page nicotinate-nucleotide diphosphorylase (carboxylating) activity (Q21025) (wbeditentity-create:2|en: nicotinate-nucleotide diphosphorylase (carboxylating) activity, Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.)
- 10:50, 15 February 2024 Fire talk contribs created page Translations:Diabetes/26/ja (Created page with "以下は、糖尿病のリスクを高める可能性のある疾患のリストである： {{Col-float-begin}} * β細胞機能の遺伝的欠陥 ** 若年性成熟期発症糖尿病 ** ミトコンドリアDNA変異 * インスリン処理またはインスリン作用における遺伝的欠陥 ** プロインスリン変換の欠陥 ** インスリン遺伝子変異 ** インスリン受容体の突然...")
- 10:44, 15 February 2024 Fire talk contribs created page hypoxanthine phosphoribosyltransferase activity (Q21024) (wbeditentity-create:2|en: hypoxanthine phosphoribosyltransferase activity, Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.)
- 10:43, 15 February 2024 Fire talk contribs created page Translations:Diabetes/25/ja (Created page with "糖尿病の一部の症例は、体の組織受容体がインスリンに反応しないために起こる（インスリンレベルが正常であっても、これが2型糖尿病との違いである）；このような型は非常にまれである。遺伝子変異（常染色体またはミトコンドリア）によりβ細胞の機能に異常が生じることがある。インスリン作用の異常も遺伝...")
- 10:38, 15 February 2024 Fire talk contribs created page anthranilate phosphoribosyltransferase activity (Q21023) (wbeditentity-create:2|en: anthranilate phosphoribosyltransferase activity, Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.)
- 10:36, 15 February 2024 Fire talk contribs created page Translations:Diabetes/24/ja (Created page with "===その他の型=== 若年性成熟期発症糖尿病（MODY）は、まれな常染色体優性遺伝型の糖尿病であり、インスリン産生障害を引き起こすいくつかの単一遺伝子変異のうちの1つが原因である。主な3つの糖尿病型に比べ発症頻度はかなり低く、全症例の1～2％である。この病名は、その性質に関する初期の仮...")
- 10:34, 15 February 2024 Fire talk contribs created page amidophosphoribosyltransferase activity (Q21022) (wbeditentity-create:2|en: amidophosphoribosyltransferase activity, Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.)
- 10:33, 15 February 2024 Fire talk contribs created page Translations:Diabetes/23/ja (Created page with "妊娠糖尿病は一過性のものかもしれないが、未治療の場合、胎児または母親の健康を損なう可能性がある。胎児へのリスクとしては、巨大児（高出生体重）、先天性心疾患や中枢神経系の異常、骨格筋の奇形などがある。胎児の血中インスリン濃度が上昇すると、胎児のsurfacta...")
- 10:28, 15 February 2024 Fire talk contribs created page adenine phosphoribosyltransferase activity (Q21021) (wbeditentity-create:2|en: adenine phosphoribosyltransferase activity, Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.)
- 10:27, 15 February 2024 Fire talk contribs created page Translations:Diabetes/22/ja (Created page with "===妊娠糖尿病=== {{Main/ja|Gestational diabetes/ja}} 妊娠糖尿病は、いくつかの点で2型糖尿病に似ており、比較的不十分なインスリン分泌と反応性の組み合わせが関与している。妊娠糖尿病は全妊娠の約2-10%にみられ、分娩後に改善または消失することがある。妊娠24～28週頃からすべての妊婦が検査を受けることが推奨されている。この時期にインス...")
- 10:25, 15 February 2024 Fire talk contribs created page ATP phosphoribosyltransferase activity (Q21020) (wbeditentity-create:2|en: ATP phosphoribosyltransferase activity, Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.)
- 10:23, 15 February 2024 Fire talk contribs created page Translations:Diabetes/21/ja (Created page with "抗精神病薬の副作用（特に代謝異常、脂質異常症、体重増加）や不健康な生活習慣（食生活の乱れや体活動の低下など）は潜在的な危険因子である。")
- 10:22, 15 February 2024 Fire talk contribs created page purine phosphoribosyltransferase activity (Q21019) (wbeditentity-create:2|en: purine phosphoribosyltransferase activity, Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate)
- 10:21, 15 February 2024 Fire talk contribs created page xanthine phosphoribosyltransferase activity (Q21018) (wbeditentity-create:2|en: xanthine phosphoribosyltransferase activity, Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate.)
- 10:20, 15 February 2024 Fire talk contribs created page 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-) (Q21017) (wbeditentity-create:2|en: 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-), chemical compound)
- 10:19, 15 February 2024 Fire talk contribs created page nicotinamide phosphoribosyltransferase activity (Q21016) (wbeditentity-create:2|en: nicotinamide phosphoribosyltransferase activity, Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide.)
- 10:17, 15 February 2024 Fire talk contribs created page Translations:Diabetes/20/ja (Created page with "虐待、ネグレクト（育児放棄）、家庭内の困難を含む幼少期の不利な体験は、その後の人生で2型糖尿病になる可能性を32％増加させ、中でもネグレクトの影響が最も強い。")
- 10:15, 15 February 2024 Fire talk contribs created page 2''-O-succinyl-ADP-D-ribose(3-) (Q21015) (wbeditentity-create:2|en: 2''-O-succinyl-ADP-D-ribose(3-), chemical compound)
- 10:14, 15 February 2024 Fire talk contribs created page Translations:Diabetes/19/ja (Created page with "砂糖入り飲料などの食事要因はリスクの増加と関連している。食事中の脂肪の種類も重要であり、飽和脂肪やトランス脂肪酸はリスクを増加させ、多価不飽和脂肪酸や一価不飽和脂肪酸はリスクを減少させる。白米の食べ過ぎは、特に中国人と日本人の...")
- 10:12, 15 February 2024 Fire talk contribs created page peptidyl-lysine modification (Q21014) (wbeditentity-create:2|en: peptidyl-lysine modification, The modification of peptidyl-lysine.)
- 10:10, 15 February 2024 Fire talk contribs created page Translations:Diabetes/18/ja (Created page with "2型糖尿病は主に生活習慣と遺伝に起因する。2型糖尿病の発症には、肥満（肥満度指数が30以上で定義される）、身体活動の不足、ダイエットの不良、ストレス、都市化など、多くの生活習慣要因が重要であることが知られている。過剰な体脂肪は、中国系...")
- 10:09, 15 February 2024 Fire talk contribs created page macromolecule deacylation (Q21013) (wbeditentity-create:2|en: macromolecule deacylation, The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.)
- 10:08, 15 February 2024 Fire talk contribs created page protein deacylation (Q21012) (wbeditentity-create:2|en: protein deacylation, The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.)
- 10:08, 15 February 2024 Fire talk contribs created page protein desuccinylation (Q21011) (wbeditentity-create:2|en: protein desuccinylation, The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein.)
- 10:07, 15 February 2024 Fire talk contribs created page peptidyl-lysine desuccinylation (Q21010) (wbeditentity-create:2|en: peptidyl-lysine desuccinylation, The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein.)
- 10:07, 15 February 2024 Fire talk contribs created page protein-succinyllysine desuccinylase activity (Q21009) (wbeditentity-create:2|en: protein-succinyllysine desuccinylase activity, Catalysis of the reaction: protein-succinyllysine + H2O => protein-lysine + succinate. This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide.)
- 10:05, 15 February 2024 Fire talk contribs created page Translations:Diabetes/17/ja (Created page with "===2型=== {{Main/ja|Type 2 diabetes/ja}} thumb|インスリンの分泌が減少したり、インスリンの受容体に対する作用が弱くなると、血液中のブドウ糖含量が高くなる。 2型糖尿病はインスリン抵抗性を特徴とし、インスリン分泌の相対的低下と合併することがある。インスリンに対する体組織の反応性の欠陥は、insulin...")
- 10:00, 15 February 2024 Fire talk contribs created page N1-3Hmethylnicotinamide (Q21008) (wbeditentity-create:2|en: N1-3Hmethylnicotinamide, chemical compound)
- 09:57, 15 February 2024 Fire talk contribs created page nicotinamide N-methyltransferase activity (Q21007) (wbeditentity-create:2|en: nicotinamide N-methyltransferase activity, Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine.)
- 09:54, 15 February 2024 Fire talk contribs created page nicotinamidase activity (Q21006) (wbeditentity-create:2|en: nicotinamidase activity, Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.)
- 09:52, 15 February 2024 Fire talk contribs created page Translations:Diabetes/16/ja (Created page with "1型糖尿病はどの年齢でも発症する可能性があり、かなりの割合が成人期に診断される。成人の潜在性自己免疫性糖尿病（LADA）は、1型糖尿病が成人で発症した場合に適用される診断用語である。この違いから、この病態を「1.5型糖尿病」と非公式に呼ぶ人もいる。LADAを発症した成人は、当初、原因ではなく年齢から2型糖...")
- 09:50, 15 February 2024 Fire talk contribs created page nicotinate transport (Q21005) (wbeditentity-create:2|en: nicotinate transport, The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.)
- 09:49, 15 February 2024 Fire talk contribs created page nicotinate transmembrane transporter activity (Q21004) (wbeditentity-create:2|en: nicotinate transmembrane transporter activity, Enables the directed movement of nicotinate into, out of or within a cell, or between cells.)
- 09:49, 15 February 2024 Fire talk contribs created page Translations:Diabetes/15/ja (Created page with "===1型=== {{Main/ja|Type 1 diabetes/ja}} 1型糖尿病は糖尿病患者の5～10％を占め、20歳未満で診断される最も一般的なタイプである。しかし、成人になってから発症することも珍しくないため、「若年発症型糖尿病」という古い用語はもはや使われていない。この疾患は、膵島のインスリンを産生するβ細胞が失われ、重篤なインス...")
- 09:44, 15 February 2024 Fire talk contribs created page nicotinate biosynthetic process (Q21003) (wbeditentity-create:2|en: nicotinate biosynthetic process, The chemical reactions and pathways resulting in the formation of nicotinate.)
- 09:43, 15 February 2024 Fire talk contribs created page Translations:Diabetes/14/ja (Created page with "糖尿病は世界保健機関によって6つのカテゴリーに分類されている： 糖尿病は、1型糖尿病、2型糖尿病、ハイブリッド型糖尿病（緩徐に進行する成人の免疫介在性糖尿病、ケトーシス傾向2型糖尿病を含む）、妊娠中に初めて発見された高血...")
- 09:40, 15 February 2024 Fire talk contribs created page nicotinate catabolic process (Q21002) (wbeditentity-create:2|en: nicotinate catabolic process, The chemical reactions and pathways resulting in the breakdown of nicotinate.)
- 21:01, 14 February 2024 Fire talk contribs created page nicotinate metabolic process (Q21001) (wbeditentity-create:2|en: nicotinate metabolic process, The chemical reactions and pathways involving nicotinate.)
- 21:00, 14 February 2024 Fire talk contribs created page nicotinate(1−) (Q21000) (wbeditentity-create:2|en: nicotinate(1−), anion)
- 20:59, 14 February 2024 Fire talk contribs created page nicotinic acid receptor activity (Q20999) (wbeditentity-create:2|en: nicotinic acid receptor activity, Combining with nicotinic acid to initiate a change in cell activity.)
- 20:58, 14 February 2024 Fire talk contribs created page Translations:Diabetes/13/ja (Created page with "==原因== {{Anchor|Causes}} {| class="wikitable" style="float:right; margin:10px" |+1型糖尿病と2型糖尿病の比較 |- ! 特徴 !! 1型糖尿病 !! 2型糖尿病 |- ! 発症 | 突然||徐々に |- ! 発症年齢 | ほとんどが小児 || ほとんどが成人 |- ! ボディサイズ | 痩せているか普通 || 多くの場合肥満 |- ! ケトアシドーシス | 共通 || まれ |- ! 自己抗体...")
- 20:54, 14 February 2024 Fire talk contribs created page lipid regulating agent (Q20998) (wbeditentity-create:2|en: lipid regulating agent, Substances that alter the metabolism of lipids)
- 20:50, 14 February 2024 Fire talk contribs created page nicotinic acid (Q20997) (wbeditentity-create:2|en: nicotinic acid, chemical compound)
- 20:47, 14 February 2024 Fire talk contribs created page Translations:Diabetes/12/ja (Created page with "認知障害と糖尿病には関連性があり、糖尿病患者は認知機能低下のリスクが高く、糖尿病でない人に比べて低下率が高いことが研究で示されている。この疾患はまた高齢者の転倒、特にインスリン治療を受けている人に起こりやすい。")
- 20:46, 14 February 2024 Fire talk contribs created page anti-anemic (Q20996) (wbeditentity-create:2|en: anti-anemic, drug)
