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Diabetic nephropathy/ja: Difference between revisions

Diabetic nephropathy/ja
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'''糖尿病性腎症'''（'''diabetic nephropathy'''）は、'''糖尿病性腎臓病'''とも呼ばれ、[[diabetes mellitus/ja|糖尿病]]患者に起こる[[kidney function/ja|腎機能]]の慢性的な低下である。糖尿病性腎症は、[[chronic kidney disease/ja|慢性腎臓病]]（CKD）および末期腎不全（ESRD）の世界的な主要原因である。尿中に蛋白が漏れ出し（蛋白尿またはアルブミン尿）、高血圧で血圧が上昇し、そして腎機能が低下するという3重苦は、多くの形態のCKDに共通している。[[Glomerulus/ja|糸球体]]の損傷による[[Proteinuria/ja|尿中蛋白喪失]]は大量になり、[[serum albumin/ja|血清アルブミン]]の低下を引き起こし、結果として[[Anasarca/ja|全身のむくみ（浮腫）]]、いわゆる[[nephrotic syndrome/ja|ネフローゼ症候群]]を引き起こすことがある。同様に、推定[[glomerular filtration rate/ja|糸球体濾過量]]（eGFR）は、90ml/分/1.73m<sup>2</sup>を超える正常値から15未満まで徐々に低下することがあり、その時点で患者は[[end-stage renal disease/ja|末期腎疾患]]であるといわれる。通常、何年もかけてゆっくりと進行する。
'''Diabetic nephropathy''', also known as '''diabetic kidney disease''', is the chronic loss of [[kidney function]] occurring in those with [[diabetes mellitus]]. Diabetic nephropathy is the leading causes of [[chronic kidney disease]] (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine (proteinuria or albuminuria), rising blood pressure with hypertension and then falling renal function is common to many forms of CKD. [[Proteinuria|Protein loss in the urine]] due to damage of the [[Glomerulus (kidney)|glomeruli]] may become massive, and cause a low [[serum albumin]] with resulting [[Anasarca|generalized body swelling (edema)]] so called [[nephrotic syndrome]]. Likewise, the estimated [[glomerular filtration rate]] (eGFR) may progressively fall from a normal of over 90 ml/min/1.73m<sup>2</sup> to less than 15, at which point the patient is said to have [[end-stage renal disease]]. It usually is slowly progressive over years.
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== 外部リンク ==
== External links ==
{{Medical resources
{{Medical resources
|  DiseasesDB      =
|  DiseasesDB      =
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{{Scholia|topic}}
{{Scholia|topic}}
{{Glomerular disease}}
{{Glomerular disease/ja}}
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{{Diabetes/ja}}
{{Diabetes}}
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{{二次利用|date=31 December 2023}}
{{DEFAULTSORT:Diabetic Nephropathy}}
{{DEFAULTSORT:Diabetic Nephropathy}}
[[Category:Kidney diseases]]
[[Category:Kidney diseases]]
[[Category:Vascular diseases]]
[[Category:Vascular diseases]]
[[Category:Complications of diabetes]]
[[Category:Complications of diabetes]]
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Retrieved from "https://wiki.tiffa.net/wiki/Diabetic_nephropathy/ja"