Sulbutiamine/ja: Difference between revisions

Sulbutiamine/ja
Created page with "スルブチアミン"
 
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<languages />
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{{short description|Chemical compound}}
{{Drugbox
{{Drugbox
| Verifiedfields = changed
| Verifiedfields = changed
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| IUPAC_name = [4-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-3-[2-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanyl-pent-3-enyl] 2-methylpropanoate
| IUPAC_name = [4-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-3-[2-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanyl-pent-3-enyl] 2-methylpropanoate
| image = sulbutiamine.svg
| image = sulbutiamine.svg
| alt = Skeletal formula of sulbutiamine
| alt = スルブチアミンの骨格式
| width = 240
| width = 240
| image2 = Sulbutiamine 3D spacefill.png
| image2 = Sulbutiamine 3D spacefill.png
| alt2 = Space-filling model of the sulbutiamine molecule
| alt2 = スルブチアミン分子の空間充填モデル
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<!--Clinical data-->
<!--Clinical data-->
| tradename = Arcalion, Enerion
| tradename = Arcalion, Enerion
| Drugs.com = {{drugs.com|international|sulbutiamine}}
| Drugs.com = {{drugs.com|international|sulbutiamine}}
| routes_of_administration = Oral
| routes_of_administration = Oral
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<!--Pharmacokinetic data-->
<!--Pharmacokinetic data-->
| elimination_half-life = 5 hours
| elimination_half-life = 5 hours
| excretion = [[Kidney|Renal]]
| excretion = [[Kidney|Renal]]
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<!--Identifiers-->
<!--Identifiers-->
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number_Ref = {{cascite|changed|??}}
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| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D01319
| KEGG = D01319
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<!--Chemical data-->
<!--Chemical data-->
| C=32 | H=46 | N=8 | O=6 | S=2  
| C=32 | H=46 | N=8 | O=6 | S=2  
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| synonyms =
| synonyms =
}}
}}
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'''スルブチアミン'''('''Sulbutiamine'''、商品名'''Arcalion''''''Enerion''')は、[[thiamine/ja|チアミン]](ビタミンB<sub>1</sub>)の合成誘導体である。フランスでは、虚弱や疲労の症状の治療に用いられる。 また、栄養補助食品としても販売されている。 スルブチアミンは、有用なチアミン誘導体を開発する努力の一環として日本で発見された。
'''Sulbutiamine''' (brand names '''Arcalion''', '''Enerion''') is a synthetic derivative of [[thiamine]] (vitamin B<sub>1</sub>). In France, it is used to treat symptoms of weakness or fatigue.  It is also sold as a dietary supplement.  Sulbutiamine was discovered in Japan as part of an effort to develop useful thiamine derivatives.
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