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Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 20:31, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/11/ja (Created page with "==副作用{{Anchor|Side effects}}== フェブキソスタット治療に伴う副作用には、吐き気、下痢、関節痛、頭痛、肝血清酵素値の上昇、発疹などがある。")
- 20:31, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/10/ja (Created page with "==医薬用途{{Anchor|Medical uses}}== フェブキソスタットは、慢性痛風および高尿酸血症の治療に用いられる。フェブキソスタットは通常、アロプリノールに耐えられない人にのみ推奨される。米国国立医療技術評価機構は、フェブキソスタットは標準用量のアロプリノールよ...")
- 20:29, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/20/ja (Created page with "米国でジェネリック医薬品になる前の2010年には、アロプリノールが1ヵ月あたり約14ドルだったのに対し、この薬は1ヵ月あたり約{{US$|160}}だった。")
- 20:29, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/19/ja (Created page with "== 社会と文化{{Anchor|Society and culture}} == === 経済学=== 英国では、NICEはフェブキソスタットの方がアロプリノールよりも費用対便益比が高いと判断し、その上でフェブキソスタットをアロプリノールを使用できない人の第二選択薬として推奨している。")
- 20:26, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/21/ja (Created page with "===商品名=== Febuxostatは、欧州、オーストラリア、ニュージーランド、パキスタンではAdenuricとして販売されている。パキスタンではSJGの姉妹会社であるSOLACE Pharmaceuticals社によって販売されている。米国ではUloric、中南米ではGoturic、Goutex、日本ではFeburic、エジプトではDonifoxateとして発売している。")
- 20:25, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/22/ja (Created page with "{{Antigout preparations/ja}} {{Purinergics/ja}} {{Portal bar | Medicine}}")
- 20:24, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/23/ja (Created page with "Category:Antigout agents Category:Xanthine oxidase inhibitors Category:Thiazoles Category:Drugs developed by Takeda Pharmaceutical Company Category:Carboxylic acids Category:Nitriles Category:Phenol ethers")
- 20:24, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/9/ja (Created page with "<!-- History and culture --> フェブキソスタットはEUでは2008年に、米国では2009年に医薬品として承認されている。")
- 20:24, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/8/ja (Created page with "<!-- Side effects and mechanism --> 一般的な副作用には、肝障害、吐き気、関節痛、発疹などがある。重篤な副作用としては、アロプリノールと比較して死亡リスクが高まること、スティーブンス・ジョンソン症候群、アナフィラキシーなどがある。妊娠中や授乳中の使用は推奨されない。xant...")
- 20:23, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/7/ja (Created page with "<!-- Definition and medical uses --> '''フェブキソスタット'''('''Febuxostat''')は、高尿酸値による痛風の治療に長期的に使用される医薬品である。一般に、アロプリノールを服用できない人にのみ推奨される。開始当初は、痛風の再燃を防ぐためにNSAIDsなどの医薬品がしばしば推奨される。by mouth/ja|...")
- 20:21, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/6/ja (Created page with "<!-- Chemical data --> | IUPAC_name = 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-<br />1,3-thiazole-5-carboxylic acid | C=16 | H=16 | N=2 | Na= | O=3 | S=1 | smiles = N#Cc1c(OCC(C)C)ccc(c1)c2nc(c(s2)C(=O)O)C | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20) | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = BQSJTQLCZDPROO-UHFFFAOYS...")
- 20:21, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/5/ja (Created page with "<!-- Identifiers --> | IUPHAR_ligand = 6817 | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 144060-53-7 | PubChem = 134018 | DrugBank_Ref = {{drugbankcite|changed|drugbank}} | DrugBank = DB04854 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 118173 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 101V0R1N2E | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D01206 | ChEBI = 31596 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 1164729")
- 20:21, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/4/ja (Created page with "<!-- Pharmacokinetic data --> | bioavailability = ≥84% absorbed | protein_bound = 99.2% to albumin | metabolism = via CYP1A1/ja, 1A2, 2C8, 2C9, UGT1A1/ja, 1A8, 1A9 | elimination_half-life = ~5–8 hours | excretion = 尿(~49%、大部分は代謝物として、3%は未変化体として);糞便(~45%、大部分は代謝物として、12%は未変化体として)")
- 20:20, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/3/ja (Created page with "| legal_AU = S4 | legal_AU_comment = | legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> | legal_US = Rx-only | legal_EU = Rx-only | legal_status =")
- 20:20, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/2/ja (Created page with "<!-- Clinical data --> | tradename = Uloric, Adenuric, others | Drugs.com = {{drugs.com|monograph|febuxostat}} | MedlinePlus = a609020 | licence_EU = yes | DailyMedID = Febuxostat | licence_US = Febuxostat | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = 経口 | ATC_prefix = M04 | ATC_suffix = AA03 | ATC_supplemental =")
- 20:20, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/1/ja (Created page with "{{Drugbox | Verifiedfields = changed | verifiedrevid = 459437484 | image = Febuxostat.svg | alt =")
- 20:20, 22 April 2024 Fire talk contribs created page Febuxostat/ja (Created page with "フェブキソスタット") Tags: Mobile edit Mobile web edit
- 20:20, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/Page display title/ja (Created page with "フェブキソスタット")
- 20:19, 22 April 2024 Fire talk contribs marked Febuxostat for translation
- 20:19, 22 April 2024 Fire talk contribs limited languages for translatable page Febuxostat to Japanese
- 20:18, 22 April 2024 Fire talk contribs created page Category:Phenol ethers (Created page with "{{Commons category}} {{cat main|Phenol ether}} {{Distinguish|Category:Phenol esters}} This category includes chemical compounds that are '''ethers''' of '''phenols'''. Phenols include phenol (C<sub>6</sub>H<sub>5</sub>OH), benzenediol etc., and polyphenols, with and without substituents. {{Category diffuse}} {{CatAutoTOC}} Category:Aromatic ethers Category:Phenyl compounds")
- 20:18, 22 April 2024 Fire talk contribs created page Category:Drugs developed by Takeda Pharmaceutical Company (Created page with "{{Commonscat}} {{Cat main|Takeda Pharmaceutical Company}} Category:Brands by company Category:Drug brand names Category:Health care brands Brands")
- 20:17, 22 April 2024 Fire talk contribs created page Category:Antigout agents (Created page with "{{Antigout preparations|state=collapsed}} {{ATC category|M04}} {{Commons cat|Antigout agents}} These agents are used to treat gout. Category:Drugs acting on the musculoskeletal system Category:Gout")
- 20:11, 22 April 2024 Fire talk contribs created page antigout agent (Q22170) (wbeditentity-create:2|en: antigout agent, agent that increases uric acid excretion by the kidney (uricosuric agents), decreases uric acid production (antihyperuricemics), or alleviates the pain and inflammation of acute attacks of gout)
- 20:07, 22 April 2024 Fire talk contribs created page joint effusion (Q22169) (wbeditentity-create:2|en: joint effusion, effusion of watery liquid into the cavity of a joint)
- 20:01, 22 April 2024 Fire talk contribs created page crystal arthropathy (Q22168) (wbeditentity-create:2|en: crystal arthropathy, Human disease)
- 19:59, 22 April 2024 Fire talk contribs created page gout (Q22167) (wbeditentity-create:2|en: gout, medical condition that results in recurrent pain and swelling of joints)
- 19:57, 22 April 2024 Fire talk contribs created page febuxostat (Q22166) (wbeditentity-create:2|en: febuxostat, chemical compound)
- 19:55, 22 April 2024 Fire talk contribs created page Febuxostat (Created page with "{{Short description|Chemical compound}} {{Drugbox | Verifiedfields = changed | verifiedrevid = 459437484 | image = Febuxostat.svg | alt = <!-- Clinical data --> | tradename = Uloric, Adenuric, others | Drugs.com = {{drugs.com|monograph|febuxostat}} | MedlinePlus = a609020 | licence_EU = yes | DailyMedID = Febuxostat | licence_US = Febuxostat | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | ATC_prefix = M0...")
- 19:49, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/7/ja (Created page with "{| class="wikitable sortable" style="width:100%" |+XO阻害剤 |- !一般名 !先発名 !class="unsortable"| 日本 !創薬/開発 !備考 |- |allopurinol/ja |[https://gskpro.com/ja-jp/products-info/zyloric/index/ ザイロリック](Zyloric) ([https://pins.japic.or.jp/pdf/newPINS/00048894.pdf PI]) ([https://gskpro.com/content/dam/global/hcpportal/ja_JP/products-info/zyloric/zyloric_tab-if.pdf IF]) |販売 |GSK plc | |- |febuxostat/ja |[https://medical.teiji...")
- 19:48, 22 April 2024 Fire talk contribs marked Xanthine oxidase inhibitor for translation
- 19:31, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/6/ja (Created page with " Category:Uric acid")
- 19:31, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/5/ja (Created page with "{{Enzyme inhibition/ja}} {{Antigout preparations/ja}} {{Purinergics/ja}}")
- 19:31, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/4/ja (Created page with "民間療法では木生シダの''Cyathea spinulosa''(旧''Alsophila spinulosa'')が痛風に用いられてきたが、その最も活性な成分であるカフェ酸はキサンチンオキシダーゼの弱い阻害剤に過ぎない。")
- 19:30, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/3/ja (Created page with "実験では、多くの天然物が試験管内またはモデル動物(マウス、ラット)でキサンチンオキシダーゼを阻害することが発見されている。 これらには、多くの異なる果物や野菜に含まれる3つのフラボノイドが含まれる: ケンフェロール、ミリセチン、ケルセチンであ...")
- 19:27, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/2/ja (Created page with "キサンチンオキシダーゼ阻害剤には2種類ある: プリン類似体とその他である。 プリン類似体にはアロプリノール、オキシプリノール、チソプリンなどがある。 その他、フェブキソスタット、トピロキソスタット、イノシトール類(phytic acid/ja|フィチン...")
- 19:25, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/1/ja (Created page with "'''キサンチンオキシダーゼ阻害薬'''('''xanthine oxidase inhibitor''')は、プリン代謝に関与する酵素であるキサンチンオキシダーゼの活性を阻害薬する物質である。 ヒトでは、キサンチンオキシダーゼの阻害は尿酸の産生を減少させ、キサンチンオキシダーゼを阻害する...")
- 19:23, 22 April 2024 Fire talk contribs created page Xanthine oxidase inhibitor/ja (Created page with "キサンチンオキシダーゼ阻害剤") Tags: Mobile edit Mobile web edit
- 19:23, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/Page display title/ja (Created page with "キサンチンオキシダーゼ阻害剤")
- 19:22, 22 April 2024 Fire talk contribs marked Xanthine oxidase inhibitor for translation
- 19:22, 22 April 2024 Fire talk contribs limited languages for translatable page Xanthine oxidase inhibitor to Japanese
- 19:21, 22 April 2024 Fire talk contribs created page Category:Xanthine oxidase inhibitors (Created page with "{{Commons category|Xanthine oxidase inhibitors}} {{catmain|Xanthine oxidase inhibitor}} Category:Oxidoreductase inhibitors Category:Xanthines")
- 19:20, 22 April 2024 Fire talk contribs created page oxidoreductase inhibitor (Q22165) (wbeditentity-create:2|en: oxidoreductase inhibitor, class of chemical compounds with a specific biological activity)
- 19:19, 22 April 2024 Fire talk contribs created page xanthine oxidase inhibitor (Q22164) (wbeditentity-create:2|en: xanthine oxidase inhibitor, Substance that decreases activity of xanthine oxidase, an enzyme involved in purine metabolism)
- 19:18, 22 April 2024 Fire talk contribs created page Template:Purine receptor modulators/ja (Created page with "{{Navbox | name = Purine receptor modulators/ja | title = Purine receptor/jaモジュレーター | state = {{{state<includeonly>|collapsed</includeonly>}}} | listclass = hlist | groupstyle = text-align:center; | group1 = 受容体<br /><small>(リガンド)</small> | list1 = {{Navbox|child | groupstyle = text-align:center; | groupwidth = 6em; | group1 = P0 (...")
- 19:05, 22 April 2024 Fire talk contribs created page Template:Purine receptor modulators (Created page with "{{Navbox | name = Purine receptor modulators | title = Purine receptor modulators | state = {{{state<includeonly>|collapsed</includeonly>}}} | listclass = hlist | groupstyle = text-align:center; | group1 = Receptor<br /><small>(ligands)</small> | list1 = {{Navbox|child | groupstyle = text-align:center; | groupwidth = 6em; | group1 = P0 (adenine) | list1 = * '''Ag...")
- 19:04, 22 April 2024 Fire talk contribs created page Template:Purinergics/ja (Redirected page to Template:Purine receptor modulators/ja) Tag: New redirect
- 19:04, 22 April 2024 Fire talk contribs created page Template:Purinergics (Redirected page to Template:Purine receptor modulators) Tag: New redirect
- 19:03, 22 April 2024 Fire talk contribs created page Template:Antigout preparations/ja (Created page with "{{Navbox | name = Antigout preparations/ja | title = 痛風に使用される薬 (M04) | state = {{{state<includeonly>|autocollapse</includeonly>}}} | listclass = hlist | group1 = 尿酸排泄促進薬 | list1 = {{Navbox|child | group1 = 第一選択 | list1 = * Probenecid/ja * Sulfinpyrazone/ja * Benzbromarone/ja * Isobromindione/ja | group2 = 第二選択 | list2 = * Amlodipine...")
- 18:59, 22 April 2024 Fire talk contribs created page Template:Antigout preparations (Created page with "{{Navbox | name = Antigout preparations | title = Drugs used for gout (M04) | state = {{{state<includeonly>|autocollapse</includeonly>}}} | listclass = hlist | group1 = Uricosurics | list1 = {{Navbox|child | group1 = primary | list1 = * Probenecid * Sulfinpyrazone * Benzbromarone * Isobromindione | group2 = secondary | list2 = * Amlodipine * Atorvastatin * Fenofibrate * Guaifenesin...")