Main public logs

Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

20:28, 15 March 2024 Fire talk contribs created page cytochrome P450, E-class, group I, CYP2J-like (Q21502) (wbeditentity-create:2|en: cytochrome P450, E-class, group I, CYP2J-like, InterPro Family)
20:27, 15 March 2024 Fire talk contribs created page cytochrome P450, E-class, group I, CYP1 (Q21501) (wbeditentity-create:2|en: cytochrome P450, E-class, group I, CYP1, InterPro Family)
20:25, 15 March 2024 Fire talk contribs created page oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (Q21500) (wbeditentity-create:2|en: oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, class of enzymes)
20:24, 15 March 2024 Fire talk contribs created page cytochrome P450, E-class, group II (Q21499) (wbeditentity-create:2|en: cytochrome P450, E-class, group II, InterPro Family)
20:23, 15 March 2024 Fire talk contribs created page cytochrome P450, E-class, CYP52 (Q21498) (wbeditentity-create:2|en: cytochrome P450, E-class, CYP52, InterPro Family)
20:22, 15 March 2024 Fire talk contribs created page cytochrome P450, E-class, group IV (Q21497) (wbeditentity-create:2|en: cytochrome P450, E-class, group IV, InterPro Family)
20:20, 15 March 2024 Fire talk contribs created page cytochrome P450, E-class, group I (Q21496) (wbeditentity-create:2|en: cytochrome P450, E-class, group I, InterPro Family)
20:19, 15 March 2024 Fire talk contribs created page cytochrome P450, mitochondrial (Q21495) (wbeditentity-create:2|en: cytochrome P450, mitochondrial, InterPro Family)
20:17, 15 March 2024 Fire talk contribs created page cytochrome P450, B-class (Q21494) (wbeditentity-create:2|en: cytochrome P450, B-class, InterPro Family)
20:16, 15 March 2024 Fire talk contribs created page cytochrome P450, conserved site (Q21493) (wbeditentity-create:2|en: cytochrome P450, conserved site, InterPro Conserved Site)
20:14, 15 March 2024 Fire talk contribs created page cytochrome P450 superfamily (Q21492) (wbeditentity-create:2|en: cytochrome P450 superfamily, class of enzymes)
20:13, 15 March 2024 Fire talk contribs created page monooxygenase (Q21491) (wbeditentity-create:2|en: monooxygenase, class of enzymes)
20:11, 15 March 2024 Fire talk contribs created page metal-binding protein (Q21490) (wbeditentity-create:2|en: metal-binding protein, proteins or protein domains that chelate a metal ion)
20:11, 15 March 2024 Fire talk contribs created page transition metal binding protein (Q21489) (wbeditentity-create:2|en: transition metal binding protein, class of proteins)
20:10, 15 March 2024 Fire talk contribs created page iron-binding proteins (Q21488) (wbeditentity-create:2|en: iron-binding proteins)
20:07, 15 March 2024 Fire talk contribs created page cytochrome biosynthetic process (Q21487) (wbeditentity-create:2|en: cytochrome biosynthetic process, the chemical reactions and pathways resulting in the formation of a cytochrome)
16:32, 15 March 2024 Fire talk contribs created page cytochrome metabolic process (Q21486) (wbeditentity-create:2|en: cytochrome metabolic process, The chemical reactions and pathways involving a cytochrome)
16:30, 15 March 2024 Fire talk contribs created page heme protein (Q21485) (wbeditentity-create:2|en: heme protein, protein containing a heme prosthetic group)
16:29, 15 March 2024 Fire talk contribs created page cytochromes (Q21484) (wbeditentity-create:2|en: cytochromes, redox active proteins containing a heme with a Fe atom as a cofactor)
16:28, 15 March 2024 Fire talk contribs created page cytochrome P450 (Q21483) (wbeditentity-create:2|en: cytochrome P450, superfamily of enzymes containing heme as a cofactor that function as monooxygenases)
16:27, 15 March 2024 Fire talk contribs created page Template:Plain link (Created page with "{{SAFESUBST:<noinclude />#if:{{{2|{{{NAME|{{{name|}}}}}}}}} |[{{{1|{{{URL|{{{url}}}}}}}}} {{{2|{{{NAME|{{{name|}}}}}}}}}] |[{{{1|{{{URL|{{{url}}}}}}}}}] }}<noinclude> {{documentation}} </noinclude>")
16:26, 15 March 2024 Fire talk contribs created page Template:Linksearch (Created page with "{{plain link|{{fullurl:Special:Linksearch|target={{urlencode:{{{1}}}}}}} {{{2|}}}}}<noinclude> {{Documentation}} </noinclude>")
16:26, 15 March 2024 Fire talk contribs created page Template:Enum (Created page with "<includeonly>{{safesubst<noinclude/>:#invoke:Separated entries|main|separator={{safesubst<noinclude/>:#if:{{{comma|}}}|{{{comma}}}|, }}|conjunction={{safesubst<noinclude/>:#if:{{{and|}}}|{{{and}}}| and }}}}{{safesubst<noinclude/>:#if:{{{1|}}}|{{{after|}}}}}</includeonly><noinclude> {{Documentation}}</noinclude>")
16:26, 15 March 2024 Fire talk contribs created page Template:Underused external link template (Created page with "{{Ombox | type = notice | text = This external link template is underused, compared to the number of links to [{{{1|}}} the site it represents] ({{enum|{{linksearch|{{{1|}}}|check here}}|{{#if:{{{2|}}}|{{linksearch|{{{2|}}}|here}}|}}|{{#if:{{{3|}}}|{{linksearch|{{{3|}}}|here}}|}}}}). Please help convert those links to make use of this template, for ease of tracking, and ease of interoperability with Wikidata. }}<includeonly>{{#ifeq:{{lc:{{{nocat|false}}}}}|...")
16:25, 15 March 2024 Fire talk contribs created page Template:InterPro (Created page with "{{#ifeq:{{{l|}}}|n||InterPro: }}''[https://www.ebi.ac.uk/interpro/entry/{{{1}}} {{{1}}}]''<noinclude> {{documentation|content= <templatedata> { "params": { "1": { "label": "interpro accession", "example": "IPR1234567", "type": "string" }, "l": { "label": "label", "description": "put in \"n\" to hide label", "example": "n" } }, "description": "This template generates a link to InterPro by accession number.", "format": "inline" }...")
16:24, 15 March 2024 Fire talk contribs created page Template:Cytochrome P450/ja (Created page with "{{Navbox | name = Cytochrome P450/ja | title = Cytochrome/ja, oxygenase/ja: cytochrome P450/ja (ほとんどがEC1.14に所属している) | listclass = hlist | titlestyle = background:#e7dcc3 | groupstyle = background-color: AntiqueWhite | state = {{{state<includeonly>|collapsed</includeonly>}}} | group1 = CYP1 | list1 = * A1 * A2 * A5 * B1 | group2 = CYP2 | list2...")
16:18, 15 March 2024 Fire talk contribs created page Template:Cytochrome P450 (Created page with "{{Navbox | name = Cytochrome P450 | title = Cytochromes, oxygenases: cytochrome P450 (Most belong to EC 1.14) | listclass = hlist | titlestyle = background:#e7dcc3 | groupstyle = background-color: AntiqueWhite | state = {{{state<includeonly>|collapsed</includeonly>}}} | group1 = CYP1 | list1 = * A1 * A2 * A5 * B1 | group2 = CYP2 | list2 = * A6 * A7 * CYP2A13...")
16:17, 15 March 2024 Fire talk contribs created page Template:Hemeproteins/ja (Created page with "{{Navbox | name = Hemeproteins/ja | title = ヘムを含むタンパク質（ヘムタンパク質） | state = {{{state<includeonly>|autocollapse</includeonly>}}} | listclass = hlist | group1 = Globin/ja | list1 = {{Navbox|child | group1 = Hemoglobin/ja | list1 = {{Navbox|child | group1 = サブユニット | list1 = {{Navbox|child | group1 = ''16番目のアル...")
16:10, 15 March 2024 Fire talk contribs created page Template:Hemeproteins (Created page with "{{Navbox | name = Hemeproteins | title = Proteins that contain heme (hemoproteins) | state = {{{state<includeonly>|autocollapse</includeonly>}}} | listclass = hlist | group1 = Globins | list1 = {{Navbox|child | group1 = Hemoglobin | list1 = {{Navbox|child | group1 = Subunits | list1 = {{Navbox|child | group1 = ''Alpha locus on 16:'' | list1 = * ''α'' ** HBA1 ** H...")
16:09, 15 March 2024 Fire talk contribs created page Cytochrome P450 (Created page with "{{Short description|Class of enzymes}} '''Cytochromes P450''' ('''P450s''' or '''CYPs''') are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone syn...")
15:52, 15 March 2024 Fire talk contribs created page Translations:Losartan/28/ja (Created page with "ロサルタンをはじめとするアンジオテンシン受容体拮抗薬は胎児毒性を示すため、妊娠中、特に妊娠第2期と第3期は避けるべきである。")
15:52, 15 March 2024 Fire talk contribs created page Translations:Losartan/27/ja (Created page with "代謝は主にチトクロームP450によって行われる。アイソザイムのCYP2C9およびCYP3A4によって代謝される。ロサルタンおよびEXP3174の血漿中濃度のピークは、それぞれ経口投与後約1時間および3～4時間後に発現する。ロサルタンとEXP3174はともに血漿蛋白と98％以上結合している。ロサルタンは未変化体および代...")
15:51, 15 March 2024 Fire talk contribs created page Translations:Losartan/26/ja (Created page with "ロサルタンの生物学的利用能は約33％である。")
15:50, 15 March 2024 Fire talk contribs created page Translations:Losartan/25/ja (Created page with "== 薬物動態 == {{Anchor|Pharmacokinetics}} ロサルタンは経口投与後よく吸収され、有意な初回通過代謝を受けてEXP3174として指定されている5-カルボン酸代謝物を生成する。経口投与量の約14％がこの代謝物に変換され、この代謝物は長時間作用性（6～8時間）であり、AT1受容体の非競合的拮抗薬であり、ロサルタンの薬理作用に寄与する...")
15:50, 15 March 2024 Fire talk contribs created page Translations:Losartan/24/ja (Created page with "ロサルタンは尿酸排泄薬である。尿酸トランスポーター1（SLC22A12、URAT1）の特異的阻害剤として、ロサルタンは細胞内への尿酸の取り込みを阻害するため、腎臓で濾過・排泄される血液中の尿酸の量が多くなる。ロサルタンは高カリウム血症を引き起こす可能性があるため、医師による適切な監視なしにカリウム...")
15:49, 15 March 2024 Fire talk contribs created page Translations:Losartan/23/ja (Created page with "アンジオテンシンII受容体拮抗薬には、ロサルタン、バルサルタン、アジルサルタン、カンデサルタン、エプロサルタン、イルベサルタン、オルメサルタン、テルミサルタンなどがある。これらはすべて同じ作用機序を持ち、リシノプリルなどの[...")
15:47, 15 March 2024 Fire talk contribs created page Translations:Losartan/22/ja (Created page with "==作用機序== {{Anchor|Mechanism of action}} thumb|レニン-アンジオテンシン-アルドステロン系(RAAS)|alt=|612x612px ロサルタンは選択的、競合的アンジオテンシンⅡ受容体1型（AT1）拮抗薬であり、アンジオテンシンⅡに対する末端臓器の反応を低下させる。ロサルタンを投与すると、全末梢抵抗...")
15:34, 15 March 2024 Fire talk contribs created page Translations:Losartan/21/ja (Created page with "2018年11月から2019年9月にかけて、FDAはSandoz、Torrent Pharmaceuticals、Hetero Labs、Camber Pharmaceuticals、Legacy Pharmaceutical Packaging、Teva Pharmaceuticalsによるロサルタンを含む錠剤の複数のリコールを発表した、 Vivimed Life Sciences、およびMacleods Pharmaceutical Limitedは、Active...")
15:31, 15 March 2024 Fire talk contribs created page Translations:Losartan/20/ja (Created page with "===汚染=== {{See also/ja|Valsartan/ja#recalls|Angiotensin II receptor blocker/ja#recalls}}")
15:31, 15 March 2024 Fire talk contribs created page Translations:Losartan/19/ja (Created page with "=== 相互作用=== ロサルタンはフェノバルビタール、リファンピン、またはフルコナゾールと有害な相互作用を起こす可能性があり、おそらく血圧低下作用を阻害する。")
15:30, 15 March 2024 Fire talk contribs created page Translations:Losartan/18/ja (Created page with "過剰摂取は、血圧の低下、心拍数の増加、めまい、ふらつき、意識消失として現れる可能性が高い。マウスの研究では、マウスの体重を考慮した後、推奨最大用量の約44倍から170倍で致死が起こることが示された。")
13:41, 15 March 2024 Fire talk contribs created page Translations:Losartan/17/ja (Created page with "===過剰摂取===")
13:40, 15 March 2024 Fire talk contribs created page Translations:Losartan/16/ja (Created page with "===妊娠=== 2014年10月、米国食品医薬品局（FDA）は、ロサルタンは胎児毒性を引き起こす可能性があるという黒枠警告を出した。妊娠が判明次第中止すべきである。妊娠中にロサルタンを使用すると、胎児が傷害を受けたり死亡したりする可能性がある。")
13:39, 15 March 2024 Fire talk contribs created page Translations:Losartan/15/ja (Created page with "==副作用== {{Anchor|Adverse effects}} 成人におけるロサルタンの最も一般的な副作用は、上部呼吸器感染症、めまい、背部痛である。2型糖尿病や腎臓病の患者は、下痢、疲労、低血圧、低血糖、カリウム上昇、胸痛、またはアレルギー反応を経験す...")
13:38, 15 March 2024 Fire talk contribs created page Translations:Losartan/14/ja (Created page with "カルシウム拮抗薬とサイアザイド系利尿薬が（有効性とコストの両面から）ほとんどの人にとって望ましい第一選択薬であるというエビデンスがあるが、ACE阻害薬に耐えられない55歳未満の人には、ロサルタンなどのアンジオテンシンII受容体拮抗薬が第一選択薬として推奨されている。ある研究...")
13:37, 15 March 2024 Fire talk contribs created page Translations:Losartan/13/ja (Created page with "ロサルタンは、左室肥大症（心筋肥大）の患者を含む高血圧症、および2型糖尿病患者の腎機能障害に用いられる。また、糖尿病性腎症の進行を遅らせることもある。2型糖尿病、高血圧、および微量アルブミン尿（>30 mg/24時間）または蛋白尿（>900 mg/24時間）を有する患者における腎疾...")
13:36, 15 March 2024 Fire talk contribs created page Translations:Losartan/12/ja (Created page with "==医療用途== {{Anchor|Medical uses}}")
13:35, 15 March 2024 Fire talk contribs created page Translations:Losartan/11/ja (Created page with "ロサルタンは一般に、''ロサルタンカリウム''と呼ばれる、芳香族化した負電荷を持つテトラゾールの（塩基性）カリウム塩として販売されている。この分子は、カルボン酸の代わりにバイオイソステアとして使用されているテトラゾールとの拡張ビフェニル基を有する。")
13:35, 15 March 2024 Fire talk contribs created page Translations:Losartan/10/ja (Created page with "==化学== ロサルタンカリウムは化学的には2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt と表記される。化学式は{{Format molecular formula|C22H23CIKN6O}}で、分子量は422.9である。")
13:32, 15 March 2024 Fire talk contribs created page Translations:Losartan/9/ja (Created page with " ロサルタンは1986年に特許を取得し、1995年に米国で医薬品として承認された。世界保健機関の必須医薬品リストに掲載されている。ジェネリック医薬品としても販売されている。2021年には55{{nbsp}}万件以上の処方で、米国で8番目に多く処方された医薬品であった。hydrochlorothiazide/...")

Main public logs

Navigation menu

Search