Main public logs

Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

• 19:40, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/7/ja (Created page with "DPP-4を阻害する可能性のある他の化学物質には以下のものがある： * ベルベリンは、ベルベリス属の植物に含まれるアルカロイドで、ジペプチジルペプチダーゼ-4を阻害する。")
• 19:40, 12 March 2024 Fire talk contribs created page Translations:Biguanide/9/ja (Created page with "<gallery caption="bioactive biguanidines" widths="180px" heights="120px" perrow="3"> File:Metformin.svg|メトホルミンは、非対称ジメチルビグアニジンとも呼ばれる。 File:Buformin.svg|ブホルミン。ビグアニジンのブチル誘導体である。 File:Phenformin.svg|フェンフォルミン. フェネチル化ビグアニジンである。 </gallery>")
• 19:38, 12 March 2024 Fire talk contribs created page Translations:Biguanide/8/ja (Created page with "例えば、以下のようなものがある： * メトホルミン - 2型糖尿病の治療に広く用いられる。 * フェンホルミン - 毒性作用のため、ほとんどの国で市場から撤退した。 * ブホルミン - 毒性により市場から撤退した。")
• 19:37, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/6/ja (Created page with "==事例== {{Anchor|Examples}} このクラスに属する薬物は以下の通りである： * シタグリプチン (FDAは2006年に承認、Merck & Co.がJanuvia/jaとして販売している） * ビルダグリプチン（2007年EU承認、EUではNovartisがGalvusとして販売している) * サキサグリプチン（2009年FDA承認、オングリザとして販売されている） * Linaglipti...")
• 19:30, 12 March 2024 Fire talk contribs created page Translations:Biguanide/7/ja (Created page with "===抗高血糖薬=== "ビグアニジン"という用語は、特に、糖尿病または糖尿病前症の治療に用いられる経口抗高血糖薬物として機能する一群の薬物を指すことが多い。")
• 19:29, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/5/ja (Created page with "2018年のメタアナリシスでは、2型糖尿病患者の全死亡、心血管死亡、心筋梗塞、脳卒中に対するDPP-4阻害薬の好ましい効果は認められなかった。")
• 19:28, 12 March 2024 Fire talk contribs created page Translations:Biguanide/6/ja (Created page with "==ビグアニジン薬物== {{Anchor|Biguanidine drugs}} ビグアニジンのさまざまな誘導体が薬物として使用されている。")
• 19:27, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/4/ja (Created page with "グルカゴンは血糖値を上昇させ、DPP-4阻害薬はグルカゴンと血糖値を低下させる。DPP-4阻害薬の機序は、インクレチンレベル（GLP-1とGIP）を増加させ、グルカゴン放出を阻害し、その結果、インスリン分泌を増加させ、胃排出を減少させ、blood glucose/ja|血...")
• 19:26, 12 March 2024 Fire talk contribs created page Translations:Biguanide/5/ja (Created page with "ビグアナイドは1879年にBernhard Rathkeによって初めて合成された。")
• 19:25, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/3/ja (Created page with "このクラスの最初の薬物であるシタグリプチンは、2006年にFDAによって承認された。")
• 19:25, 12 March 2024 Fire talk contribs created page Translations:Biguanide/4/ja (Created page with ":<math>\mathrm{C_2H_4N_4 + NH_3 \longrightarrow C_2H_7N_5}</math>")
• 19:25, 12 March 2024 Fire talk contribs created page Translations:Biguanide/3/ja (Created page with "==合成== {{Anchor|Synthesis}} ビグアニドはジシアンジアミドとアンモニアの反応から、ピナー型のプロセスを経て得ることができる。")
• 17:36, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/2/ja (Created page with "'''ジペプチジルペプチダーゼ4阻害薬'''（'''DPP-4 inhibitor'''または'''gliptins'''）は、経口血糖降下薬の一種であり、ブロック薬である。酵素ジペプチジルペプチダーゼ-4（DPP-4）を阻害する。これらは2型糖尿病の治療に使用できる。")
• 17:35, 12 March 2024 Fire talk contribs created page Dipeptidyl peptidase-4 inhibitor/ja (Created page with "thumb|300px|right|DPP-4阻害薬とGLP-1") Tags: Mobile edit Mobile web edit
• 17:34, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/1/ja (Created page with "thumb|300px|right|DPP-4阻害薬とGLP-1")
• 17:34, 12 March 2024 Fire talk contribs created page Translations:Dipeptidyl peptidase-4 inhibitor/Page display title/ja (Created page with "ジペプチジルペプチダーゼ-4阻害剤")
• 17:34, 12 March 2024 Fire talk contribs marked Dipeptidyl peptidase-4 inhibitor for translation
• 17:34, 12 March 2024 Fire talk contribs limited languages for translatable page Dipeptidyl peptidase-4 inhibitor to Japanese
• 17:31, 12 March 2024 Fire talk contribs created page Template:Enzyme inhibition/ja (Created page with "{{Navbox | name = Enzyme inhibition/ja | title = Pharmacology/ja: 酵素阻害剤 | listclass = hlist | state = {{{state|}}} | group1 = クラス | list1 = * Competitive inhibition/ja * 非競合的阻害 * Non-competitive inhibition/ja * Suicide inhibition/ja * Mixed inhibition/ja | group2 = 基板 | list2 = {{Navbox|subgroup | group1 = Oxidoreductase/ja (EC 1) | list...")
• 17:23, 12 March 2024 Fire talk contribs created page Template:Enzyme inhibition (Created page with "{{Navbox | name = Enzyme inhibition | title = Pharmacology: enzyme inhibition | listclass = hlist | state = {{{state|}}} | group1 = Class | list1 = * Competitive inhibition * Uncompetitive inhibition * Non-competitive inhibition * Suicide inhibition * Mixed inhibition | group2 = Substrate | list2 = {{Navbox|subgroup | group1 = Oxidoreductase (EC 1) | list1 = * 1.1 Aldose...")
• 17:22, 12 March 2024 Fire talk contribs created page Dipeptidyl peptidase-4 inhibitor (Created page with "{{Short description|Enzyme blocker and diabetes treatment drug}} thumb|300px|right|DPP-4 inhibitors and GLP-1 '''Inhibitors of dipeptidyl peptidase 4''' ('''DPP-4 inhibitors''' or '''gliptins''') are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2. The first agent of the class – sitagliptin – w...")
• 17:18, 12 March 2024 Fire talk contribs created page Dipeptidyl peptidase-4 inhibitors/ja (Redirected page to ジペプチジルペプチダーゼ-4阻害剤) Tag: New redirect
• 17:18, 12 March 2024 Fire talk contribs created page Dipeptidyl peptidase-4 inhibitors (Redirected page to Dipeptidyl peptidase-4 inhibitor) Tag: New redirect
• 17:17, 12 March 2024 Fire talk contribs created page Translations:Biguanide/18/ja (Created page with "===消毒薬=== {{see also/ja|Bisbiguanide/ja}} 消毒剤クロルヘキシジン、ポリアミノプロピルビグアニド（PAPB）、ポリヘキサニド、アレキシジンはビグアニド官能基を特徴とする。")
• 17:15, 12 March 2024 Fire talk contribs created page Translations:Biguanide/19/ja (Created page with "{{oral hypoglycemics/ja}} {{antimalarials/ja}}")
• 17:15, 12 March 2024 Fire talk contribs created page Translations:Biguanide/20/ja (Created page with " Category:Guanidines Category:Substances discovered in the 19th century")
• 17:14, 12 March 2024 Fire talk contribs created page Translations:Biguanide/2/ja (Created page with "'''ビグアナイド'''（'''Biguanide'''、{{IPAc-en|b|a&|g|w|ɒ|n|aɪ|d}}）は、式HN(C(NH)NH₂)₂で表される有機化合物である。 無色の固体で、水に溶けて塩基性の高い溶液を作る。 これらの溶液はゆっくりと加水分解してアンモニアと尿素になる。")
• 17:14, 12 March 2024 Fire talk contribs created page Translations:Biguanide/1/ja (Created page with "{{chembox | Watchedfields = changed | verifiedrevid = 444387711 | ImageFile = Biguanide.svg | ImageFile_Ref = {{chemboximage|correct|??}} | ImageSize = 160 | ImageName = ビグアナイドの骨格式 | ImageFile1 = Biguanide-from-xtal-3D-bs-17.png | ImageFile1_Ref = {{chemboximage|correct|??}} | ImageSize1 = 160 | ImageName1 = ビグアナイドのボールとスティックのモデル | PIN = Imidodicarbonimidic diamide |Section1={{Chembox Identifiers | CASNo = 56-03-...")
• 17:13, 12 March 2024 Fire talk contribs created page Biguanide/ja (Created page with "ビグアナイド")
• 17:13, 12 March 2024 Fire talk contribs created page Translations:Biguanide/Page display title/ja (Created page with "ビグアナイド")
• 17:12, 12 March 2024 Fire talk contribs marked Biguanide for translation
• 17:12, 12 March 2024 Fire talk contribs limited languages for translatable page Biguanide to Japanese
• 17:11, 12 March 2024 Fire talk contribs created page Category:Substances discovered in the 19th century (Created page with "{{navseasoncats}} Category:19th century in science")
• 17:08, 12 March 2024 Fire talk contribs created page biguanide (Q21468) (wbeditentity-create:2|en: biguanide, chemical compound)
• 17:07, 12 March 2024 Fire talk contribs created page Template:Chromalveolate antiparasitics/ja (Created page with "{{Navbox | name = Chromalveolate antiparasitics/ja | title = Antiparasitic/ja – antiprotozoal agent/ja – Chromalveolata/ja 抗寄生虫薬 (P01) | listclass = hlist | state = {{{state<includeonly>|autocollapse</includeonly>}}} | group1 = 肺胞 | list1 = {{Navbox|subgroup | group1 = 哺乳綱 | list1 = {{Navbox|subgroup | group1 = Conoidasida/ja/<br>(Coccidiostat/ja) | l...")
• 16:56, 12 March 2024 Fire talk contribs created page Template:Chromalveolate antiparasitics (Created page with "{{Navbox | name = Chromalveolate antiparasitics | title = Antiparasitics – antiprotozoal agents – Chromalveolata antiparasitics (P01) | listclass = hlist | state = {{{state<includeonly>|autocollapse</includeonly>}}} | group1 = Alveo-<br>late | list1 = {{Navbox|subgroup | group1 = Apicom-<br>plexa | list1 = {{Navbox|subgroup | group1 = Conoidasida/<br>(Coccidiostats) | list1 =...")
• 16:55, 12 March 2024 Fire talk contribs created page Template:Antimalarials/ja (Created page with "{{Navbox | name = Chromalveolate antiparasitics | title = Antiparasitics – antiprotozoal agents – Chromalveolata antiparasitics (P01) | listclass = hlist | state = {{{state<includeonly>|autocollapse</includeonly>}}} | group1 = Alveo-<br>late | list1 = {{Navbox|subgroup | group1 = Apicom-<br>plexa | list1 = {{Navbox|subgroup | group1 = Conoidasida/<br>(Coccidiostats) | list1 =...")
• 16:53, 12 March 2024 Fire talk contribs created page Template:Antimalarials (Created page with "{{Navbox | name = Chromalveolate antiparasitics | title = Antiparasitics – antiprotozoal agents – Chromalveolata antiparasitics (P01) | listclass = hlist | state = {{{state<includeonly>|autocollapse</includeonly>}}} | group1 = Alveo-<br>late | list1 = {{Navbox|subgroup | group1 = Apicom-<br>plexa | list1 = {{Navbox|subgroup | group1 = Conoidasida/<br>(Coccidiostats) | list1 =...")
• 16:52, 12 March 2024 Fire talk contribs created page Template:Details/ja (Redirected page to Template:Further/ja) Tag: New redirect
• 16:52, 12 March 2024 Fire talk contribs created page Template:Details (Redirected page to Template:Further) Tag: New redirect
• 16:51, 12 March 2024 Fire talk contribs created page Biguanide (Created page with "{{short description|Chemical compound}} {{chembox | Watchedfields = changed | verifiedrevid = 444387711 | ImageFile = Biguanide.svg | ImageFile_Ref = {{chemboximage|correct|??}} | ImageSize = 160 | ImageName = Skeletal formula of biguanide | ImageFile1 = Biguanide-from-xtal-3D-bs-17.png | ImageFile1_Ref = {{chemboximage|correct|??}} | ImageSize1 = 160 | ImageName1 = Ball and stick model of biguanide | PIN = Imidodicarbonimidic diamide |Section1={{Chembox Identifiers | CA...")
• 16:35, 12 March 2024 Fire talk contribs created page Translations:Metformin/102/ja (Created page with "また、メトホルミンは糖尿病を予防するが、がんや心血管疾患のリスクは減少させないため、糖尿病でない人の寿命は延びないことを示唆する研究もある。さらに、健康な人がメトホルミンを長期間慢性的に使用すると、ビタミンB12欠乏症になる可能性を示唆する研究もある。")
• 16:35, 12 March 2024 Fire talk contribs created page Translations:Metformin/101/ja (Created page with "メトホルミンは脆弱X症候群の人の体重を減らすかもしれないが、神経症状や精神症状を改善するかどうかは不明である。メトホルミンは生体内（''線虫''およびコオロギ）で老化に対する影響について研究されている。2017年のレビューによると、メトホルミンを服用している糖尿病患者は全死...")
• 16:34, 12 March 2024 Fire talk contribs created page Translations:Discovery and development of dipeptidyl peptidase-4 inhibitors/65/ja (Created page with "4. キナゾリン基はTrp629残基とπスタッキング相互作用を起こす。")
• 16:34, 12 March 2024 Fire talk contribs created page Translations:Metformin/100/ja (Created page with "== 研究 メトホルミンは、以下のような他の複数の疾患に対する効果について研究されている： * 非アルコール性脂肪性肝疾患 * 思春期早発症 * ガン * 糖尿病患者における心臓血管疾患 * 老化")
• 16:32, 12 March 2024 Fire talk contribs created page Translations:Discovery and development of dipeptidyl peptidase-4 inhibitors/64/ja (Created page with "3. ウラシル基はTyr547残基とπスタッキング相互作用を起こす。")
• 16:32, 12 March 2024 Fire talk contribs created page Translations:Metformin/99/ja (Created page with "2020年8月、Bayshore Pharmaceuticals社は2つのロットの錠剤を回収した。")
• 16:32, 12 March 2024 Fire talk contribs created page Translations:Discovery and development of dipeptidyl peptidase-4 inhibitors/63/ja (Created page with "2. ブチル-2-ニル基はS1-ポケットを占める。")
• 16:31, 12 March 2024 Fire talk contribs created page Translations:Metformin/98/ja (Created page with "2020年7月、ルピン・ファーマシューティカルズ社は、検査したサンプルから許容できないほど高濃度のNDMAが検出されたため、すべてのロット（バッチ）のメトホルミンを回収した。")
• 16:31, 12 March 2024 Fire talk contribs created page Translations:Discovery and development of dipeptidyl peptidase-4 inhibitors/62/ja (Created page with "1. アミノ基はGlu205、Glu206、Tyr662とも相互作用する。")