Main public logs

Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

• 21:38, 10 March 2024 Fire talk contribs created page glucagon secretion (Q21376) (wbeditentity-create:2|en: glucagon secretion, The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).)
• 21:36, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/21/ja (Created page with "==病態生理学== {{Anchor|Pathophysiology}} 正常な代謝では、上昇した血中グルコースは、膵臓にあるランゲルハンス島のβ細胞にインスリンを血液中に放出するように指示する。インスリンは体内のインスリン感受性組織（主に骨格筋肉細胞、脂肪組織、肝臓）にグルコースを吸収させ...")
• 21:33, 10 March 2024 Fire talk contribs created page peptide hormone binding (Q21375) (wbeditentity-create:2|en: peptide hormone binding, Interacting selectively and non-covalently with any peptide with hormonal activity in animals.)
• 21:33, 10 March 2024 Fire talk contribs created page glucagon family peptide binding (Q21374) (wbeditentity-create:2|en: glucagon family peptide binding, Interacting selectively and non-covalently with glucagon, a polypeptide hormone involved in glucose response. It is produced by pancreatic alpha cells and raises the concentration of glucose in the blood.)
• 21:31, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/20/ja (Created page with "=== 遺伝学 === いくつかの遺伝子座がインスリン抵抗性と関連していることが明らかにされている。これには、インスリン抵抗性に関連するNAT2、GCKR、IGFI遺伝子近傍の遺伝子座の変異が含まれる。さらなる研究により、これらの遺伝子近傍の遺伝子座がインスリン抵抗性と関連していることが示された。しかし、これらの遺伝子座はインスリン抵抗性の遺...")
• 21:28, 10 March 2024 Fire talk contribs created page G protein-coupled peptide receptor activity (Q21373) (wbeditentity-create:2|en: G protein-coupled peptide receptor activity, Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.)
• 21:27, 10 March 2024 Fire talk contribs created page glucagon receptor activity (Q21372) (wbeditentity-create:2|en: glucagon receptor activity, Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.)
• 21:25, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/19/ja (Created page with "=== 炎症 === 感染症などの急性または慢性の炎症は、インスリン抵抗性を引き起こす可能性がある。腫瘍壊死因子α|TNF-αは、脂肪分解を促進し、インスリンシグナル伝達を阻害し、GLUT4の発現を低下させることにより、インスリン抵抗性を促進する可能性のあるサイトカインである。")
• 21:23, 10 March 2024 Fire talk contribs created page GPCR ligand binding (Q21371) (wbeditentity-create:2|en: GPCR ligand binding, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-500792))
• 21:23, 10 March 2024 Fire talk contribs created page Class B/2 (Secretin family receptors) (Q21370) (wbeditentity-create:2|en: Class B/2 (Secretin family receptors), An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-373080))
• 21:22, 10 March 2024 Fire talk contribs created page Glucagon-type ligand receptors (Q21369) (wbeditentity-create:2|en: Glucagon-type ligand receptors, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-420092))
• 21:21, 10 March 2024 Fire talk contribs created page Glucagon binds to Glucagon receptor (Q21368) (wbeditentity-create:2|en: Glucagon binds to Glucagon receptor, An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-163625))
• 21:21, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/18/ja (Created page with "=== ミトコンドリア機能障害=== 異なる方法論による複数の研究から、ミトコンドリアの機能障害がインスリン抵抗性の病因において極めて重要な役割を果たしている可能性が示唆されている。ミトコンドリアの機能障害は、活性酸素種の形成、遺伝的要因、加齢、ミトコンドリアの生合成の低下から生じる可能性が...")
• 21:18, 10 March 2024 Fire talk contribs created page The Ligand:GPCR:Gq complex dissociates (Q21367) (wbeditentity-create:2|en: The Ligand:GPCR:Gq complex dissociates, An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-749452))
• 21:16, 10 March 2024 Fire talk contribs created page Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Q21366) (wbeditentity-create:2|en: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-379048))
• 21:12, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/52/ja (Created page with "現代の仮説では、インスリン代謝は社会生態学的適応であり、インスリンは身体の様々な構成要素へのエネルギー配分を区別する手段であり、インスリン感受性はエネルギーをどこに振り向けるかを操作する適応であるとされている。行動スイッチ仮説では、インスリン抵抗性が生殖戦略と行動方法を変える2つの方法をもたらすと仮定している。この2...")
• 21:11, 10 March 2024 Fire talk contribs created page Signal Transduction (Q21365) (wbeditentity-create:2|en: Signal Transduction, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-162582))
• 21:11, 10 March 2024 Fire talk contribs created page Signaling by GPCR (Q21364) (wbeditentity-create:2|en: Signaling by GPCR, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-372790))
• 21:09, 10 March 2024 Fire talk contribs created page GPCR downstream signalling (Q21363) (wbeditentity-create:2|en: GPCR downstream signalling, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-388396))
• 21:08, 10 March 2024 Fire talk contribs created page G alpha (q) signalling events (Q21362) (wbeditentity-create:2|en: G alpha (q) signalling events, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-416476))
• 21:08, 10 March 2024 Fire talk contribs created page Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Q21361) (wbeditentity-create:2|en: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq, An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-749448))
• 21:05, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/51/ja (Created page with "ピマ・インディアンの研究では、インスリン感受性の高い人ほど体重が多く、逆にインスリン抵抗性のある人ほど平均体重が少ないという、ニールとは相反する結果が出ている。")
• 21:04, 10 March 2024 Fire talk contribs created page Metabolism of proteins (Q21360) (wbeditentity-create:2|en: Metabolism of proteins, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-392499))
• 21:03, 10 March 2024 Fire talk contribs created page Peptide hormone metabolism (Q21359) (wbeditentity-create:2|en: Peptide hormone metabolism, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2980736))
• 21:03, 10 March 2024 Fire talk contribs created page Synthesis, secretion, and deacylation of Ghrelin (Q21358) (wbeditentity-create:2|en: Synthesis, secretion, and deacylation of Ghrelin, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-422085))
• 21:02, 10 March 2024 Fire talk contribs created page Acyl Ghrelin and C-Ghrelin are secreted (Q21357) (wbeditentity-create:2|en: Acyl Ghrelin and C-Ghrelin are secreted, An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-422048))
• 21:00, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/50/ja (Created page with "J.V.ニールは、もともと古代人の祖先が飢饉の多かった時代には、グルコースの貯蔵量を増やすメカニズムを持つ遺伝子が有利だったと仮定している。しかし、現代の環境ではそうではない。")
• 20:57, 10 March 2024 Fire talk contribs created page Metabolism (Q21356) (wbeditentity-create:2|en: Metabolism, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-1430728))
• 20:56, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/49/ja (Created page with "インスリン抵抗性が進化的適応であるという他の有力な考えには、倹約遺伝子仮説がある。この仮説は、もしインスリン抵抗性と2型糖尿病に遺伝的要素があるならば、これらの表現型は淘汰されるべきであるというものである。しかし、正常血糖集団においても糖尿病集団においても、平均インスリン抵抗性は増加している。")
• 16:33, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/48/ja (Created page with "=== 適応的説明 === インスリン抵抗性も肥満も、それ自体は代謝異常ではなく、脂質毒性（血流や組織中の脂質の危険なレベル）から臓器を守るための、持続的なカロリー過剰に対する適応反応に過ぎないと主張する学者もいる： 「したがって、肥満は病態や疾患とみなされるべきではなく、むしろ持続的なカロリー過剰に対する正常な生...")
• 16:32, 10 March 2024 Fire talk contribs created page energy reserve metabolic process (Q21355) (wbeditentity-create:2|en: energy reserve metabolic process, The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.)
• 16:31, 10 March 2024 Fire talk contribs created page Integration of energy metabolism (Q21354) (wbeditentity-create:2|en: Integration of energy metabolism, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-163685))
• 16:29, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/53/ja (Created page with "== こちらも参照 == {{col div|colwidth=40em}} * Pancreatic beta cell function/ja * Chronic Somogyi rebound/ja * Hyperinsulinemia/ja * Resistin/ja * Chronic stress/ja * 全身性炎症 * 概日リズムの乱れ * Advanced glycation end-products/ja * Polycystic ovary syndrome/ja {{colend}}")
• 16:29, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/54/ja (Created page with "== さらに読む == {{refbegin}} * {{cite journal | vauthors = Reaven GM | title = The insulin resistance syndrome: definition and dietary approaches to treatment | journal = Annual Review of Nutrition | volume = 25 | pages = 391–406 | year = 2005 | pmid = 16011472 | doi = 10.1146/annurev.nutr.24.012003.132155 | s2cid = 24849146 | type = review }} * {{cite journal | vauthors = Rao G | title = Insulin resistance syndrome | journal = American Family Physician | volume...")
• 16:28, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/55/ja (Created page with "== 外部リンク == {{Medical resources | DiseasesDB = | ICD10 = | ICD9 = | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = med | eMedicineTopic = 1173 }} * {{Curlie|Health/Conditions_and_Diseases/Endocrine_Disorders/Pancreas/Insulin_Resistance/}} * {{Cite book | url = http://diabetes.niddk.nih.gov/dm/pubs/insulinresistance/ | title = Diabetes | contribution = Insulin resistance | publisher = NIH | location = US | access-date = 2013-04-25 | archive-date = 2015-05-13...")
• 16:28, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/56/ja (Created page with "{{diabetes/ja}} {{Disease of the pancreas and glucose metabolism/ja}}")
• 16:28, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/57/ja (Created page with "{{DEFAULTSORT:Insulin Resistance}} Category:Diabetes")
• 16:26, 10 March 2024 Fire talk contribs created page response to glucagon (Q21353) (wbeditentity-create:2|en: response to glucagon, Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.)
• 16:25, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/17/ja (Created page with "===疾患=== 多嚢胞性卵巣症候群や非アルコール性脂肪性肝疾患（NAFLD）はインスリン抵抗性と関連している。また、C型肝炎は2型糖尿病やインスリン抵抗性を3～4倍発症しやすくする。")
• 16:22, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/16/ja (Created page with "レプチンは、ob遺伝子と脂肪細胞から産生されるホルモンである。その生理的役割は、満腹時に身体に警告を発して空腹感を調節することである。")
• 16:20, 10 March 2024 Fire talk contribs created page response to peptide hormone (Q21352) (wbeditentity-create:2|en: response to peptide hormone, Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides)
• 16:19, 10 March 2024 Fire talk contribs created page cellular response to peptide hormone stimulus (Q21351) (wbeditentity-create:2|en: cellular response to peptide hormone stimulus, Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secret)
• 16:18, 10 March 2024 Fire talk contribs created page cellular response to glucagon stimulus (Q21350) (wbeditentity-create:2|en: cellular response to glucagon stimulus, Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.)
• 16:17, 10 March 2024 Fire talk contribs created page Glucagon signaling in metabolic regulation (Q21349) (wbeditentity-create:2|en: Glucagon signaling in metabolic regulation, An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-163359))
• 16:16, 10 March 2024 Fire talk contribs created page glucagon (Q21348) (wbeditentity-create:2|en: glucagon, mammalian protein found in human, mouse, and rat)
• 16:13, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/15/ja (Created page with "肥満手術後のヒトや十二指腸を外科的に切除したラットにおけるインスリン感受性の有意な改善に基づいて、小腸の初期部分の粘膜で何らかの物質が産生され、体細胞がインスリン抵抗性になるようにシグナルを送っていると提唱されている。産生される組織が除去されれば、シグナルは止まり、体細胞は正常なインスリン...")
• 16:12, 10 March 2024 Fire talk contribs created page protein maturation (Q21347) (wbeditentity-create:2|en: protein maturation, Any process leading to the attainment of the full functional capacity of a protein.)
• 16:11, 10 March 2024 Fire talk contribs created page Translations:Insulin resistance/14/ja (Created page with "コルチゾールはインスリンに対抗し、肝糖新生の亢進、末梢でのグルコース利用の低下、インスリン抵抗性の亢進を引き起こす。これは、グルコーストランスポーター（特にGLUT4）の細胞膜へのトランスロケーションを減少させることによって行われる。")
• 16:09, 10 March 2024 Fire talk contribs created page proteolysis (Q21346) (wbeditentity-create:2|en: proteolysis, the hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds)
• 16:09, 10 March 2024 Fire talk contribs created page protein processing (Q21345) (wbeditentity-create:2|en: protein processing, Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.)