Main public logs
Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 14:01, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/7/ja (Created page with "摂取されたメチルコバラミンがそのまま補因子として使われるのではなく、まずMMACHCによってコブ(II)アラミンに変換される。コブ(II)アラミンはその後、他の2つの形態、アデノシルコバラミンとメチルコバラミンに変換され、補因子として使用される。つまり、メチルコバラミンがまず脱アルキル化され、その後再生される。")
- 14:01, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/6/ja (Created page with "メチルコバラミンもまた、末梢神経障害、糖尿病性神経障害の治療や、筋萎縮性側索硬化症の予備治療として用いられる。")
- 14:01, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/5/ja (Created page with "メチルコバラミンは生理学的にはビタミンB{{sub|12}}と同等であり、ビタミンB{{sub|12}}の摂取不足から生じる病態（ビタミンB<sub>12</sub>欠乏症）の予防や治療に用いることができる。")
- 14:00, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/14/ja (Created page with "== こちらも参照 == *Cobamamide/ja *シアノコバラミン *ヒドロキソコバラミン *ビタミンB12 *Cobalamin biosynthesis/ja")
- 14:00, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/15/ja (Created page with "{{Vitamin/ja}} {{Enzyme cofactors/ja}}")
- 14:00, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/16/ja (Created page with "Category:B vitamins Category:Cofactors Category:Methylating agents Category:Organocobalt compounds Category:Vitamin B12")
- 14:00, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/4/ja (Created page with "<!--Identifiers--> | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 13422-55-4 | ATC_prefix = B03 | ATC_suffix = BA05 | PubChem = 6436232 | ChemSpiderID = 29368587 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|changed|FDA}} | UNII = BR1SN1JS2W | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1697757 | StdInChI=1S/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26...")
- 13:59, 7 April 2024 FuzzyBot talk contribs created page Methylcobalamin/en (Updating to match new version of source page) Tags: Mobile edit Mobile web edit
- 13:59, 7 April 2024 Fire talk contribs created page Methylcobalamin/ja (Created page with "{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 416418921 | IUPAC_name = carbanide; cobalt(3+); | image = Methylcobalamin.png | image2 = Mecobalamin 3D sticks.png") Tags: Mobile edit Mobile web edit
- 13:58, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/3/ja (Created page with "<!--Pharmacokinetic data--> | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion =")
- 13:58, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/2/ja (Created page with "<!--Clinical data--> | tradename = Cobolmin | Drugs.com = {{drugs.com|international|methylcobalamin}} | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | pregnancy_category = | legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> | legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> | legal_US = OTC | legal_status = | routes_of_admi...")
- 13:57, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/1/ja (Created page with "{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 416418921 | IUPAC_name = carbanide; cobalt(3+); | image = Methylcobalamin.png | image2 = Mecobalamin 3D sticks.png")
- 13:57, 7 April 2024 Fire talk contribs created page Translations:Methylcobalamin/Page display title/ja (Created page with "メチルコバラミン")
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/16/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/15/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/14/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/13/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/12/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/11/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/10/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/9/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/8/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/7/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/6/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/5/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/4/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/3/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/2/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/1/en (Importing a new version from external source)
- 13:57, 7 April 2024 FuzzyBot talk contribs created page Translations:Methylcobalamin/Page display title/en (Importing a new version from external source)
- 13:57, 7 April 2024 Fire talk contribs marked Methylcobalamin for translation
- 13:57, 7 April 2024 Fire talk contribs limited languages for translatable page Methylcobalamin to Japanese
- 13:56, 7 April 2024 Fire talk contribs created page Category:Methylating agents (Created page with "{{Commons cat|Methylating agents}} Category:Methylation Category:Alkylating agents")
- 13:54, 7 April 2024 Fire talk contribs created page methylcobalamin (Q21867) (wbeditentity-create:2|en: methylcobalamin, chemical compound)
- 13:53, 7 April 2024 Fire talk contribs created page Methylcobalamin (Created page with "{{short description|Form of vitamin B12}} {{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 416418921 | IUPAC_name = carbanide; cobalt(3+); | image = Methylcobalamin.png | image2 = Mecobalamin 3D sticks.png <!--Clinical data--> | tradename = Cobolmin | Drugs.com = {{drugs.com|international|methylcobalamin}} | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | pregnancy_category = | legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6...")
- 13:50, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/19/ja (Created page with "細胞内のビタミンB<sub>12</sub>は、メチルコバラミンと5-デオキシアデノシルコバラミンという2つの活性型補酵素で維持されている。ビタミンB<sub>12</sub>が欠乏すると、メチルマロニル-CoAからスクシニル-CoAへの変換が起こらなくなり、メチルマロニル-CoAの蓄積と異常な脂肪酸合成が起こる。もう一つの酵素反応では、メチル...")
- 13:48, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/18/ja (Created page with "コバラミンは、ポルフィリンのようなコリン核を特徴とし、ベンズイミダゾリルヌクレオチドと可変残基(R)基に結合した単一のコバルト原子を含む：CNCbl、メチルコバラミン、5-デオキシアデノシルコバラミン、OHCblである。血清中では、ヒド...")
- 13:44, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/17/ja (Created page with "==作用機序== {{Anchor|Mechanism of action}} ビタミンB<sub>12</sub>はコバラミンと呼ばれる化合物群を指し、人体内では様々な相互変換可能な形で存在する。コバラミンは葉酸とともに、染色体の複製と分裂が起こる細胞、特に骨髄と骨髄系細胞において、DNAの合成に必要な必須補因子である。Cofactor (bioch...")
- 10:50, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/16/ja (Created page with "==特性== {{Anchor|Properties}} ヒドロキソコバラミン酢酸塩は、無臭で暗赤色の斜方晶結晶である。注射製剤は暗赤色の透明な溶液として現れる。分配係数は{{gaps|1.133|e=-5}}、pKaは7.65である。")
- 10:49, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/15/ja (Created page with "薬物は尿を赤く変色させ（色尿）、それが血尿のように見えることがある。")
- 10:49, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/14/ja (Created page with "==副作用== {{Anchor|Side effects}} ヒドロキソコバラミンの急性毒性プロファイルに関する文献データによると、局所的・全身的な曝露では一般に安全とみなされている。ヒドロキソコバラミンがキレート化によってシアン化合物を迅速に捕捉し、解毒する能力は、シアン化合物曝露に対する静脈内（IV）治療薬としての使用を支持するために、14...")
- 10:47, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/13/ja (Created page with "===ヒドロキソコバラミン注射剤=== ヒドロキソコバラミン注射剤は、ビタミンB<sub>12</sub>欠乏の以下の原因を改善するために使用される（リストはU.S.Food and Drug Administration発行の薬物処方ラベルから引用）。 * 厳格な菜食主義者やその母乳で育てられた乳児に起こるビタミンB<sub>12</sub>の食事性欠乏（単独...")
- 10:44, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/12/ja (Created page with "===シアン中毒=== ヒドロキソコバラミン（Hydroxocobalamin）は、シアン中毒の患者に対する第一選択薬である。ヒドロキソコバラ ミンはシアンをはるかに毒性の低いシアノコバラミンに変換する。シアノコバラミンは腎で排出される。ヒドロキソコバラミンが第一選択薬となったのは、その有害リスクプロファイルの低さ...")
- 10:43, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/11/ja (Created page with "新たにビタミンB<sub>12</sub>欠乏症と診断された患者（通常、血清中濃度が200 pg/ml未満と定義される）では、消耗したコバラミン貯蔵量を補充するために、1日1,000 μg（1 mg）までのヒドロキソコバラミン注射を毎日IM注射する。神経症状がある場合は、毎日の治療後、6ヵ月間は週1回または隔週1回の注射を行い、その後月1回のIM注射を開始する。...")
- 10:43, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/10/ja (Created page with "===ビタミンB<sub>12</sub>欠乏症=== ビタミンB<sub>12</sub>欠乏症の治療の標準治療は、ヒドロキソコバラミン（OHCbl）の筋肉内（IM）または静脈内（IV）注射である。というのも、大半の症例は経腸ルート（腸）での吸収不良によるものだからである。本態性コバラミン代謝性疾患の小児患者、青酸中毒によるタバコ弱視のビタミ...")
- 10:41, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/9/ja (Created page with "==医療用途== {{Anchor|Medical uses}} thumb|left|標準状態でのヒドロキソコバラミン は暗赤色の結晶からなる固体である。 thumb|upright|ヒドロキソコバラミン注射液USP（1000μg/mL）は、赤色の澄明な液体である。写真は皮下注射用に調製された500μgのB-12である。")
- 10:40, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/8/ja (Created page with "<!-- History, society and culture --> ヒドロキソコバラミンは1949年に初めて単離された。WHO必須医薬品リストに掲載されている。ヒドロキソコバラミンはジェネリック医薬品として販売されている。")
- 10:39, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/7/ja (Created page with "<!-- Side effects and mechanism --> 副作用は一般的にほとんどない。下痢、気分の悪さ、ほてり、かゆみ、低血中カリウム、アレルギー反応、高血圧などである。通常量は妊娠中に安全と考えられている。この薬物による過量投与や毒性は報告されていない。ヒドロ...")
- 10:38, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/20/ja (Created page with "{{Vitamin/ja}} {{Antidotes/ja}} {{Portal bar | Medicine}}")
- 10:37, 7 April 2024 Fire talk contribs created page Translations:Hydroxocobalamin/21/ja (Created page with "Category:Antidotes Category:B vitamins Category:Drugs developed by Pfizer Category:Drugs developed by Merck Category:Wikipedia medicine articles ready to translate Category:Tetrapyrroles Category:Vitamin B12 Category:World Health Organization essential medicines")
