Main public logs

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• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/24/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/23/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/22/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/21/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/20/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/19/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/18/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/17/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/16/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/15/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/14/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/13/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/12/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/11/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/10/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/9/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/8/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/7/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/6/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/5/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/4/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/3/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/2/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/1/en (Importing a new version from external source)
• 22:55, 22 April 2024 FuzzyBot talk contribs created page Translations:Collagen/Page display title/en (Importing a new version from external source)
• 22:55, 22 April 2024 Fire talk contribs marked Collagen for translation
• 22:55, 22 April 2024 Fire talk contribs limited languages for translatable page Collagen to Japanese
• 22:51, 22 April 2024 Fire talk contribs created page Saimiri transformation-associated protein (Q22175) (wbeditentity-create:2|en: Saimiri transformation-associated protein, InterPro Family)
• 22:50, 22 April 2024 Fire talk contribs created page Collagen triple helix repeat (Q22174) (wbeditentity-create:2|en: Collagen triple helix repeat, InterPro Repeat)
• 22:49, 22 April 2024 Fire talk contribs created page collagen triple helix repeat, protein family (Q22173) (wbeditentity-create:2|en: collagen triple helix repeat, protein family, protein family)
• 22:48, 22 April 2024 Fire talk contribs created page extracellular matrix proteins (Q22172) (wbeditentity-create:2|en: extracellular matrix proteins, macromolecules forming an intricate meshwork in which cells are embedded to construct tissues)
• 22:47, 22 April 2024 Fire talk contribs created page collagen (Q22171) (wbeditentity-create:2|en: collagen, group of fibrous proteins that occur in vertebrates as the chief constituent of connective tissue fibrils and in bones and yield gelatin and glue upon boiling with water)
• 22:46, 22 April 2024 Fire talk contribs created page Template:See also cat (Redirected page to Template:Category see also) Tag: New redirect
• 22:46, 22 April 2024 Fire talk contribs created page Category:Aging-related proteins (Created page with "{{See also cat|Aging-related genes}} Category:Senescence Category:Proteins by function")
• 22:45, 22 April 2024 Fire talk contribs created page Template:Category main section (Created page with "{{Hatnote|extraclasses=relarticle mainarticle|The main section for this category is {{#ifeq:{{{article|}}}|no|on the page|in the article}} [[{{{1}}}]], in the section titled [[{{{1}}}#{{{2}}}|{{{2}}}]].}}<noinclude> <!-- Add categories and interwikis to the /doc subpage, not here! --> {{Documentation}} </noinclude>")
• 22:45, 22 April 2024 Fire talk contribs created page Category:Structural proteins (Created page with "{{Category main section|Protein|Structural proteins}} {{Commons category|Structural proteins}} Category:Proteins by function")
• 22:44, 22 April 2024 Fire talk contribs created page Category:Collagens (Created page with "{{Commons category|Collagen}} Category:Extracellular matrix proteins")
• 22:43, 22 April 2024 Fire talk contribs created page Template:Fibrous proteins/ja (Created page with "{{Navbox | name = Fibrous proteins/ja | title = タンパク質: scleroprotein/ja | bodyclass = hlist | titlestyle = background:#e7dcc3 | basestyle = background-color: AntiqueWhite | group1 = 細胞外<br>マトリックス | list1 = {{Navbox|subgroup | groupstyle = background-color: AntiqueWhite | group1 = コラーゲン | list1 = {{Navbox|subgroup | groupstyle = background-color: AntiqueWhite | group1...")
• 22:36, 22 April 2024 Fire talk contribs created page Template:Fibrous proteins (Created page with "{{Navbox | name = Fibrous proteins | title = Protein: scleroproteins | bodyclass = hlist | titlestyle = background:#e7dcc3 | basestyle = background-color: AntiqueWhite | group1 = Extracellular <br>matrix | list1 = {{Navbox|subgroup | groupstyle = background-color: AntiqueWhite | group1 = Collagen | list1 = {{Navbox|subgroup | groupstyle = background-color: AntiqueWhite | group1 = Fibril forming...")
• 22:35, 22 April 2024 Fire talk contribs created page Collagen (Created page with "{{Short description|Most abundant structural protein in animals}} thumb|upright=1.5|Tropocollagen molecule: three left-handed procollagens (red, green, blue) join to form a right-handed triple helical tropocollagen. '''Collagen''' ({{IPAc-en|ˈ|k|ɒ|l|ə|dʒ|ə|n}}) is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the...")
• 20:40, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/18/ja (Created page with "Ipsenは2008年4月に欧州医薬品庁からフェブキソスタットの販売承認を取得し、武田薬品工業は2009年2月にFDAの承認を取得、帝人は2011年に日本の当局から承認を取得した。Ipsenは2009年にMenariniに欧州での独占的な権利をライセンスした。帝人は中国と東南アジアでの販売でアステラス製薬と提携...")
• 20:39, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/17/ja (Created page with "==歴史{{Anchor|History}}== thumb|right|250px|FEBURIC (Febuxostat) 80 mgタブレット フェブキソスタットは1998年に日本の製薬会社帝人の科学者によって発見された。帝人はこの薬物をアメリカではTAP Pharmaceuticals、ヨーロッパではIpsenと提携した。")
• 20:38, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/16/ja (Created page with "thumb|right|ヒトにおける[[active metabolite/ja|活性代謝物：67M-1、67M-2、67M-4（上から下へ）]] フェブキソスタットにはヒトにおいて3つの活性代謝物があり、それらは主に多くのチトクロームP450肝酵素（CYP1A1、1A2、2C8、2C9）によって生成される。そのうちの1つはdicarboxyl...")
• 20:36, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/15/ja (Created page with "=== 薬物動態 === 経口摂取後、フェブキソスタット用量の少なくとも84％が腸管で吸収され、60～90分後に最高血漿中濃度に達する。脂肪分の多い食事と一緒に摂取した場合、フェブキソスタットの体内濃度は低くなるが、これは臨床的な意義はないと考えられている。血中では、物質の99.2％が血漿タンパク質アルブミンと結合し...")
• 20:35, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/14/ja (Created page with "== 薬理学{{Anchor|Pharmacology}} == === 作用機序=== フェブキソスタットはキサンチンオキシダーゼの非プリン選択的阻害薬である。キサンチンオキシダーゼの活性部位であるモリブデンプテリン中心を非競合的阻害することで作用する。キサンチンオキシダーゼは、ヒポキサンチンと[...")
• 20:33, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/13/ja (Created page with "==薬物相互作用{{Anchor|Drug interactions}}== フェブキソスタットは、テオフィリンおよび化学療法薬、すなわちアザチオプリンおよび6-メルカプトプリンとの併用禁忌である。")
• 20:32, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/12/ja (Created page with "2017年11月、FDAは、安全性臨床試験の予備的結果において、心血管疾患の既往歴のある患者において、アロプリノールと比較してフェブキソスタットで心臓関連死のリスクが増加したことを示す安全性警告を発した。FDAは2009年にこの薬が承認された際、武田薬品にこの安全性試験の実施を要求した。承認前に実施された臨床試験では、フ...")
• 20:31, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/11/ja (Created page with "==副作用{{Anchor|Side effects}}== フェブキソスタット治療に伴う副作用には、吐き気、下痢、関節痛、頭痛、肝血清酵素値の上昇、発疹などがある。")
• 20:31, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/10/ja (Created page with "==医薬用途{{Anchor|Medical uses}}== フェブキソスタットは、慢性痛風および高尿酸血症の治療に用いられる。フェブキソスタットは通常、アロプリノールに耐えられない人にのみ推奨される。米国国立医療技術評価機構は、フェブキソスタットは標準用量のアロプリノールよ...")
• 20:29, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/20/ja (Created page with "米国でジェネリック医薬品になる前の2010年には、アロプリノールが1ヵ月あたり約14ドルだったのに対し、この薬は1ヵ月あたり約{{US$|160}}だった。")