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Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 20:21, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/4/ja (Created page with "<!-- Pharmacokinetic data --> | bioavailability = ≥84% absorbed | protein_bound = 99.2% to albumin | metabolism = via CYP1A1/ja, 1A2, 2C8, 2C9, UGT1A1/ja, 1A8, 1A9 | elimination_half-life = ~5–8 hours | excretion = 尿(~49%、大部分は代謝物として、3%は未変化体として);糞便(~45%、大部分は代謝物として、12%は未変化体として)")
- 20:20, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/3/ja (Created page with "| legal_AU = S4 | legal_AU_comment = | legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> | legal_US = Rx-only | legal_EU = Rx-only | legal_status =")
- 20:20, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/2/ja (Created page with "<!-- Clinical data --> | tradename = Uloric, Adenuric, others | Drugs.com = {{drugs.com|monograph|febuxostat}} | MedlinePlus = a609020 | licence_EU = yes | DailyMedID = Febuxostat | licence_US = Febuxostat | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = 経口 | ATC_prefix = M04 | ATC_suffix = AA03 | ATC_supplemental =")
- 20:20, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/1/ja (Created page with "{{Drugbox | Verifiedfields = changed | verifiedrevid = 459437484 | image = Febuxostat.svg | alt =")
- 20:20, 22 April 2024 Fire talk contribs created page Febuxostat/ja (Created page with "フェブキソスタット") Tags: Mobile edit Mobile web edit
- 20:20, 22 April 2024 Fire talk contribs created page Translations:Febuxostat/Page display title/ja (Created page with "フェブキソスタット")
- 20:19, 22 April 2024 Fire talk contribs marked Febuxostat for translation
- 20:19, 22 April 2024 Fire talk contribs limited languages for translatable page Febuxostat to Japanese
- 20:18, 22 April 2024 Fire talk contribs created page Category:Phenol ethers (Created page with "{{Commons category}} {{cat main|Phenol ether}} {{Distinguish|Category:Phenol esters}} This category includes chemical compounds that are '''ethers''' of '''phenols'''. Phenols include phenol (C<sub>6</sub>H<sub>5</sub>OH), benzenediol etc., and polyphenols, with and without substituents. {{Category diffuse}} {{CatAutoTOC}} Category:Aromatic ethers Category:Phenyl compounds")
- 20:18, 22 April 2024 Fire talk contribs created page Category:Drugs developed by Takeda Pharmaceutical Company (Created page with "{{Commonscat}} {{Cat main|Takeda Pharmaceutical Company}} Category:Brands by company Category:Drug brand names Category:Health care brands Brands")
- 20:17, 22 April 2024 Fire talk contribs created page Category:Antigout agents (Created page with "{{Antigout preparations|state=collapsed}} {{ATC category|M04}} {{Commons cat|Antigout agents}} These agents are used to treat gout. Category:Drugs acting on the musculoskeletal system Category:Gout")
- 20:11, 22 April 2024 Fire talk contribs created page antigout agent (Q22170) (wbeditentity-create:2|en: antigout agent, agent that increases uric acid excretion by the kidney (uricosuric agents), decreases uric acid production (antihyperuricemics), or alleviates the pain and inflammation of acute attacks of gout)
- 20:07, 22 April 2024 Fire talk contribs created page joint effusion (Q22169) (wbeditentity-create:2|en: joint effusion, effusion of watery liquid into the cavity of a joint)
- 20:01, 22 April 2024 Fire talk contribs created page crystal arthropathy (Q22168) (wbeditentity-create:2|en: crystal arthropathy, Human disease)
- 19:59, 22 April 2024 Fire talk contribs created page gout (Q22167) (wbeditentity-create:2|en: gout, medical condition that results in recurrent pain and swelling of joints)
- 19:57, 22 April 2024 Fire talk contribs created page febuxostat (Q22166) (wbeditentity-create:2|en: febuxostat, chemical compound)
- 19:55, 22 April 2024 Fire talk contribs created page Febuxostat (Created page with "{{Short description|Chemical compound}} {{Drugbox | Verifiedfields = changed | verifiedrevid = 459437484 | image = Febuxostat.svg | alt = <!-- Clinical data --> | tradename = Uloric, Adenuric, others | Drugs.com = {{drugs.com|monograph|febuxostat}} | MedlinePlus = a609020 | licence_EU = yes | DailyMedID = Febuxostat | licence_US = Febuxostat | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | ATC_prefix = M0...")
- 19:49, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/7/ja (Created page with "{| class="wikitable sortable" style="width:100%" |+XO阻害剤 |- !一般名 !先発名 !class="unsortable"| 日本 !創薬/開発 !備考 |- |allopurinol/ja |[https://gskpro.com/ja-jp/products-info/zyloric/index/ ザイロリック](Zyloric) ([https://pins.japic.or.jp/pdf/newPINS/00048894.pdf PI]) ([https://gskpro.com/content/dam/global/hcpportal/ja_JP/products-info/zyloric/zyloric_tab-if.pdf IF]) |販売 |GSK plc | |- |febuxostat/ja |[https://medical.teiji...")
- 19:48, 22 April 2024 Fire talk contribs marked Xanthine oxidase inhibitor for translation
- 19:31, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/6/ja (Created page with " Category:Uric acid")
- 19:31, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/5/ja (Created page with "{{Enzyme inhibition/ja}} {{Antigout preparations/ja}} {{Purinergics/ja}}")
- 19:31, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/4/ja (Created page with "民間療法では木生シダの''Cyathea spinulosa''(旧''Alsophila spinulosa'')が痛風に用いられてきたが、その最も活性な成分であるカフェ酸はキサンチンオキシダーゼの弱い阻害剤に過ぎない。")
- 19:30, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/3/ja (Created page with "実験では、多くの天然物が試験管内またはモデル動物(マウス、ラット)でキサンチンオキシダーゼを阻害することが発見されている。 これらには、多くの異なる果物や野菜に含まれる3つのフラボノイドが含まれる: ケンフェロール、ミリセチン、ケルセチンであ...")
- 19:27, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/2/ja (Created page with "キサンチンオキシダーゼ阻害剤には2種類ある: プリン類似体とその他である。 プリン類似体にはアロプリノール、オキシプリノール、チソプリンなどがある。 その他、フェブキソスタット、トピロキソスタット、イノシトール類(phytic acid/ja|フィチン...")
- 19:25, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/1/ja (Created page with "'''キサンチンオキシダーゼ阻害薬'''('''xanthine oxidase inhibitor''')は、プリン代謝に関与する酵素であるキサンチンオキシダーゼの活性を阻害薬する物質である。 ヒトでは、キサンチンオキシダーゼの阻害は尿酸の産生を減少させ、キサンチンオキシダーゼを阻害する...")
- 19:23, 22 April 2024 Fire talk contribs created page Xanthine oxidase inhibitor/ja (Created page with "キサンチンオキシダーゼ阻害剤") Tags: Mobile edit Mobile web edit
- 19:23, 22 April 2024 Fire talk contribs created page Translations:Xanthine oxidase inhibitor/Page display title/ja (Created page with "キサンチンオキシダーゼ阻害剤")
- 19:22, 22 April 2024 Fire talk contribs marked Xanthine oxidase inhibitor for translation
- 19:22, 22 April 2024 Fire talk contribs limited languages for translatable page Xanthine oxidase inhibitor to Japanese
- 19:21, 22 April 2024 Fire talk contribs created page Category:Xanthine oxidase inhibitors (Created page with "{{Commons category|Xanthine oxidase inhibitors}} {{catmain|Xanthine oxidase inhibitor}} Category:Oxidoreductase inhibitors Category:Xanthines")
- 19:20, 22 April 2024 Fire talk contribs created page oxidoreductase inhibitor (Q22165) (wbeditentity-create:2|en: oxidoreductase inhibitor, class of chemical compounds with a specific biological activity)
- 19:19, 22 April 2024 Fire talk contribs created page xanthine oxidase inhibitor (Q22164) (wbeditentity-create:2|en: xanthine oxidase inhibitor, Substance that decreases activity of xanthine oxidase, an enzyme involved in purine metabolism)
- 19:18, 22 April 2024 Fire talk contribs created page Template:Purine receptor modulators/ja (Created page with "{{Navbox | name = Purine receptor modulators/ja | title = Purine receptor/jaモジュレーター | state = {{{state<includeonly>|collapsed</includeonly>}}} | listclass = hlist | groupstyle = text-align:center; | group1 = 受容体<br /><small>(リガンド)</small> | list1 = {{Navbox|child | groupstyle = text-align:center; | groupwidth = 6em; | group1 = P0 (...")
- 19:05, 22 April 2024 Fire talk contribs created page Template:Purine receptor modulators (Created page with "{{Navbox | name = Purine receptor modulators | title = Purine receptor modulators | state = {{{state<includeonly>|collapsed</includeonly>}}} | listclass = hlist | groupstyle = text-align:center; | group1 = Receptor<br /><small>(ligands)</small> | list1 = {{Navbox|child | groupstyle = text-align:center; | groupwidth = 6em; | group1 = P0 (adenine) | list1 = * '''Ag...")
- 19:04, 22 April 2024 Fire talk contribs created page Template:Purinergics/ja (Redirected page to Template:Purine receptor modulators/ja) Tag: New redirect
- 19:04, 22 April 2024 Fire talk contribs created page Template:Purinergics (Redirected page to Template:Purine receptor modulators) Tag: New redirect
- 19:03, 22 April 2024 Fire talk contribs created page Template:Antigout preparations/ja (Created page with "{{Navbox | name = Antigout preparations/ja | title = 痛風に使用される薬 (M04) | state = {{{state<includeonly>|autocollapse</includeonly>}}} | listclass = hlist | group1 = 尿酸排泄促進薬 | list1 = {{Navbox|child | group1 = 第一選択 | list1 = * Probenecid/ja * Sulfinpyrazone/ja * Benzbromarone/ja * Isobromindione/ja | group2 = 第二選択 | list2 = * Amlodipine...")
- 18:59, 22 April 2024 Fire talk contribs created page Template:Antigout preparations (Created page with "{{Navbox | name = Antigout preparations | title = Drugs used for gout (M04) | state = {{{state<includeonly>|autocollapse</includeonly>}}} | listclass = hlist | group1 = Uricosurics | list1 = {{Navbox|child | group1 = primary | list1 = * Probenecid * Sulfinpyrazone * Benzbromarone * Isobromindione | group2 = secondary | list2 = * Amlodipine * Atorvastatin * Fenofibrate * Guaifenesin...")
- 18:59, 22 April 2024 Fire talk contribs created page Xanthine oxidase inhibitor (Created page with "<languages /> <translate> {{Short description|Substance that decreases activity of xanthine oxidase, an enzyme involved in purine metabolism}} A '''xanthine oxidase inhibitor''' is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism. In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are Indica...")
- 18:50, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/29/ja (Created page with "===温度=== 低温は急性痛風の引き金になることが報告されている。例えば、冷たい水の中で一日過ごした後、翌朝痛風の発作が起こる。これは、常温以下の温度で組織内に尿酸結晶が温度依存的に析出するためと考えられている。 したがって、予防の目的のひとつは手足を温かく保つことであり、お湯に浸かることが治療につながることもある。")
- 18:50, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/28/ja (Created page with "===pH=== 血清pHは安全かつ容易に変化させることはできない。pHを変化させる治療法は主に尿のpHを変化させ、尿毒症治療の合併症として考えられる尿中の尿酸増加による尿酸腎結石の形成を抑制する(腎石症を参照)。同様の効果を持つ医薬品にはアセタゾラミドがある。")
- 18:49, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/27/ja (Created page with "高尿酸血症に対する非薬物療法には、低プリン体食(痛風を参照)およびさまざまな栄養補助食品がある。リチウムは尿酸の溶解性を改善するため、リチウム塩による治療も行われている。")
- 18:49, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/26/ja (Created page with "これらの医薬品の中には、適応症として使用されるものもあれば、適応外として使用されるものもある。血液透析を受けている人では、セベラマーは、明らかに腸内で尿酸塩を吸着することによって血清尿酸を有意に減少させることができる。女性では、combined oral contraceptive pill/ja|経口避...")
- 18:47, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/25/ja (Created page with "==== 尿酸排泄促進薬 ==== 尿崩症薬(ベンズブロマロン、ベンジオダロン、プロベネシド、レシヌラド、スルフィンピラゾン、エテベンシド、ゾキサゾラミン、チクリナフェン)は、一度腎臓で血液から濾過された尿酸の再吸収を減少させることにより...")
- 18:45, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/24/ja (Created page with "==== キサンチンオキシダーゼ阻害薬==== アロプリノール、フェブキソスタット、トピロキソスタットなどのキサンチンオキシダーゼ阻害薬は、キサンチンオキシダーゼを阻害することによって尿酸の産生を減少させる。")
- 18:44, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/23/ja (Created page with "=== 尿酸濃度を下げることを目的とした医薬品 === 高尿酸血症の治療に用いられる医薬品は2つに分類される: キサンチンオキシダーゼ阻害薬と尿酸降下薬である。痛風の発作を繰り返す人には、これら2つのカテゴリーの薬物のいずれかが推奨される。無症候性高尿酸血症の人がこれらの医薬品を服用す...")
- 18:44, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/22/ja (Created page with "==治療{{Anchor|Treatment}}==")
- 18:43, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/21/ja (Created page with "==診断{{Anchor|Diagnosis}}== 高尿酸血症は、血液検査や尿検査で発見することができる。")
- 18:43, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/20/ja (Created page with "飢餓は、体内の(プリン体を多く含む)組織をエネルギーとして代謝させる。したがって、高プリン体食と同様に、飢餓は尿酸に変換されるプリン体の量を増加させる。炭水化物を欠く超低カロリー食は極端な高尿酸血症を誘発する;炭水化物をある程度含むと(そしてタンパク質を減らすと)高尿酸血...")
- 18:42, 22 April 2024 Fire talk contribs created page Translations:Hyperuricemia/19/ja (Created page with "果糖の大量摂取は高尿酸血症に大きく寄与する。米国での大規模研究では、1日4本以上の砂糖入り清涼飲料水の摂取で、高尿酸血症のオッズ比は1.82であった。尿酸産生の増加は、フルクトース代謝産物によるプリン代謝の妨害の結果である。この妨害には二重作用があり、ATPからイノシン、した...")