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- 08:48, 8 April 2024 Fire talk contribs marked Nicotinamide mononucleotide for translation
- 08:48, 8 April 2024 Fire talk contribs limited languages for translatable page Nicotinamide mononucleotide to Japanese
- 08:47, 8 April 2024 Fire talk contribs created page Category:Anti-aging substances (Created page with "{{Commons}} Chemical substances that (a) have been shown to increase longevity or retard senescence or some aspects thereof, (b) are widely believed to do so or (c) are widely promoted as such. Some of these substances are endogenous. Category:Chemical substances Category:Life extension Category:Senescence")
- 08:46, 8 April 2024 Fire talk contribs created page Category:Nucleotides (Created page with "{{Commons cat|Nucleotides}} A '''nucleotide''' is an organic molecule consisting of a nitrogenous heterocyclic nucleobase (a purine or a pyrimidine), a pentose sugar (deoxyribose in DNA or ribose in RNA), and a phosphate or polyphosphate group. As a short-hand, the nucleotides that form the rungs of the ladder in the DNA double-helix are often referred to by biologists, as their base pair identity such as adenine (''A'...")
- 08:43, 8 April 2024 Fire talk contribs created page nicotinamide mononucleotide transmembrane transporter activity (Q21882) (wbeditentity-create:2|en: nicotinamide mononucleotide transmembrane transporter activity, Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 po)
- 08:41, 8 April 2024 Fire talk contribs created page nicotinamide mononucleotide transport (Q21881) (wbeditentity-create:2|en: nicotinamide mononucleotide transport, The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, i)
- 08:40, 8 April 2024 Fire talk contribs created page nicotinamide mononucleotide transmembrane transport (Q21880) (wbeditentity-create:2|en: nicotinamide mononucleotide transmembrane transport, The process in which nicotinamide mononucleotide is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide)
- 08:39, 8 April 2024 Fire talk contribs created page nicotinamide mononucleotide (Q21879) (wbeditentity-create:2|en: nicotinamide mononucleotide, chemical compound, nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose)
- 08:37, 8 April 2024 Fire talk contribs created page Template:Expand language (Created page with "{{ {{{|safesubst:}}}#invoke:Unsubst||date=__DATE__ |$B= <!--{{Expand language}} begin-->{{ambox | name = {{{name|Expand language}}} | subst = <includeonly>{{{subst|{{subst:substcheck}}}}}</includeonly> | type = notice | image = 50x40px|alt=|link= | text = {{hidden| style = font-size:100%; padding: 0px; | 1 =<!-- Multiple languages --> {{#if:{{{langcode2|}}}|You can help <b>expand this {{#ifeq:yes|{{yesno|def=|{{{section|}}}}}...")
- 08:37, 8 April 2024 Fire talk contribs created page Template:Expand Japanese (Created page with "{{ {{{|safesubst:}}}#invoke:Unsubst||date=__DATE__ |$B= {{Expand language |langcode=ja |otherarticle={{{1|}}} |section={{{section|}}} |date={{{date|}}} |fa={{{fa|}}} |topic={{#switch: {{lc:{{{topic}}}}} | anime | manga = Anime and manga | culture = Culture | geo = Geography | gov = Government | hist = History | sci = Science | sport = Sports | tech = Technology | transport = Transport | vg = Video game }} |nodoc={{{nodoc|}}} |no interwiki={{{no interwiki|}}} }} }}")
- 08:37, 8 April 2024 Fire talk contribs created page Nicotinamide mononucleotide (Created page with "{{Expand Japanese|ニコチンアミドモノヌクレオチド|date=September 2018}} {{Chembox <!-- Images --> | ImageFile = Nicotinamide mononucleotide.svg | ImageSize = 220px <!-- Names --> | IUPACName = 3-Carbamoyl-1-(5-''O''-phosphono-β-<small>D</small>-ribofuranosyl)pyridin-1-ium | SystematicName = [(2''R'',3''S'',4''R'',5''R'')-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate | OtherNames = {{unbulleted list | Nicotinamide rib...")
- 08:32, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/16/ja (Created page with "==安全性に関する指定{{Anchor|Safety designations}}== 2016年、米国食品医薬品局(FDA)は、塩化ニコチンアミドリボシド(NRC、Niagen™)の製剤について、クロマデックスにGenerally recognized as safe(GRAS)ステータスを付与した。2015年と2017年に米国食品医薬品局から栄養補助食品に使用する新規栄養成分(NDI)に指定された。2018年にはカ...")
- 08:31, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/15/ja (Created page with "==商業化{{Anchor|Commercialization}}== 2012年7月にChromaDexが特許をライセンスし、NRをTruNiagenとして市場に出すためのプロセス開発を開始した。ChromaDex社は2016年以来、ニコチンアミドリボシドサプリメントの権利をめぐってElysium Health社と特許紛争を続けている。")
- 08:29, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/14/ja (Created page with "ニコチンアミドリボシド(NR)は、ニコチンアミドリボシドキナーゼ酵素(NRK1およびNRK2)によるリン酸化を含む付加的な経路を経て利用される。酵母では、NRはヌクレオシダーゼPnp1、Urh1、Meu1によって分解された後、Preiss-Handler経路とニコチンアミダーゼPnc1の作用によってNAD⁺に変換されることも示されている。")
- 08:29, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/13/ja (Created page with "450px|thumb|center|NRK1/2が仲介するNRからNAD+への経路")
- 08:29, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/12/ja (Created page with "ニコチンアミドリボシド(NR)は現在、NAD+前駆体であることが知られており、ビタミンB3をNAD+に変換する生合成経路に関与している。NAD+は哺乳類では主にトリプトファンからデノボで合成され、ニコチン酸(NA)からPriess-Handler経路を経て、あるいはニコチンアミド(NAM)からサルベージ経路を経て合成される。")
- 08:29, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/11/ja (Created page with "==生合成== {{Anchor|Biosynthesis}} {{Main/ja|Nicotinamide adenine dinucleotide/ja#Biosynthesis}}")
- 08:28, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/10/ja (Created page with "代謝研究により、かつては安定分子と考えられていたNAD+は、代謝のホメオスタシスを維持するために厳密な調節が必要なほど、絶えず入れ替わり使用されていることが示されている。 哺乳類におけるNRの利用には、外因性の食物源と、中間体を再利用する内因性のサルベージ過程の両方が関与している可能性がある。 NR代謝とさまざまなNAD+経路の相互...")
- 08:27, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/9/ja (Created page with "哺乳類における研究によると、NRK1は細胞質タンパク質であり、''Nmrk1''遺伝子によってコードされている。ほとんどの組織に存在するが、主に肝臓と腎臓に多い。NRK2タンパク質は心筋を含む筋肉組織に関係している可能性がある。これは''Nmrk2''遺伝子によってコードされ、代謝ストレスや細胞損傷の場合に、より高発現するようである。 組織の種類によ...")
- 08:27, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/8/ja (Created page with "2004年、ニコチンアミドリボシド(NR)が真核生物における追加のNAD+前駆体として同定されたとき、これまで知られていなかった経路が報告された。 NRは現在ではビタミンB<sub>3</sub>の一種として認識されており、牛乳にもヒトの母乳にも含まれている。 細胞内に取り込まれると、NRはニコチンアミドリボシドキナーゼ酵素(NRK1...")
- 08:26, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/7/ja (Created page with "NAD+代謝に関するその後の研究により、NAD+の利用可能性を維持するために細胞や組織が用いる調節経路が同定された。NAD+とその前駆体であるニコチン酸(NA)およびニコチンアミド(NAM)は、細胞内の酸化/還元反応およびATP合成において重要な補因子であることが示されている。 真核生物で特徴づけられる古典的なNAD+合成...")
- 08:25, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/6/ja (Created page with "真核生物におけるNAD前駆体としてのニコチンアミドリボシド(NR)の同定は、ペラグラの研究から発展した。ペラグラはNAD+欠乏に関連する最初の疾患であった。1914年にジョセフ・ゴールドバーガーによって栄養欠乏と関連づけられ、1937年にはコンラッド・エルヴェヘムによってNiacin (substan...")
- 08:24, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/5/ja (Created page with "''インフルエンザ菌''はニコチン酸(NA)、ニコチンアミド(NAM)、トリプトファン(Trp)やアスパラギン酸(Asp)のようなアミノ酸では増殖できない。 ''インフルエンザ菌''は、環境中の他の細胞からのNAD前駆体のサルベージに完全に依存している。")
- 08:23, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/4/ja (Created page with "==歴史== ニコチンアミドリボシド(NR)は、細菌と真核生物の両方においてサルベージNAD合成に関与するNAD前駆体として同定されている。 細菌では、1944年に''インフルエンザ菌''の培養に必要な増殖因子として初めて報告され、''インフルエンザ菌''は増殖するためにX因子(ヘミン)とV因子(NAD)...")
- 08:22, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/3/ja (Created page with "==化学== {{Anchor|Chemistry}} ニコチンアミドリボシドの分子量が255.25g/molであるのに対し、塩化物塩の分子量は290.70g/molである。そのため、100 mgの塩化ニコチンアミドリボシドは88 mgのニコチンアミドリボシドを提供する。")
- 08:21, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/17/ja (Created page with "== こちらも参照 == * ニコチンアミドモノヌクレオチド * ナイアシン * ニコチンアミド * ビタミンB3 * Nicotinamide adenine dinucleotide/ja * Sirtuin/ja * Poly (ADP-ribose) polymerase/ja")
- 08:21, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/18/ja (Created page with "Category:Ribosides Category:Nicotinamides")
- 08:21, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/2/ja (Created page with "'''ニコチンアミドリボシド'''('''NR'''、'''SR647''')は、ピリジン-ヌクレオシドの一種で、ビタミンB<sub>3</sub>の一種である。ニコチンアミドアデニンジヌクレオチド、またはNAD+の前駆体として機能する。")
- 08:20, 8 April 2024 Fire talk contribs created page Nicotinamide riboside/ja (Created page with "{{Chembox | Name = | ImageFile = nicotinamide-beta-riboside.svg | ImageAlt = | ImageCaption = | ImageFile1 = Nicotinamideriboside.png | ImageAlt1 = | ImageCaption1 = | IUPACName = 3-Carbamoyl-1-(β-<small>D</small>-ribofuranosyl)pyridin-1-ium | SystematicName = 3-Carbamoyl-1-[(2''R'',3''R'',4''S'',5''R'')-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium | OtherNames = 1-(β-<small>D</small>-Ribofuranosyl)nicotinamide; ''N''-Ribosylnicotinamide |Section1={{Che...") Tags: Mobile edit Mobile web edit
- 08:20, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/1/ja (Created page with "{{Chembox | Name = | ImageFile = nicotinamide-beta-riboside.svg | ImageAlt = | ImageCaption = | ImageFile1 = Nicotinamideriboside.png | ImageAlt1 = | ImageCaption1 = | IUPACName = 3-Carbamoyl-1-(β-<small>D</small>-ribofuranosyl)pyridin-1-ium | SystematicName = 3-Carbamoyl-1-[(2''R'',3''R'',4''S'',5''R'')-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium | OtherNames = 1-(β-<small>D</small>-Ribofuranosyl)nicotinamide; ''N''-Ribosylnicotinamide |Section1={{Che...")
- 08:19, 8 April 2024 Fire talk contribs created page Translations:Nicotinamide riboside/Page display title/ja (Created page with "ニコチンアミドリボシド")
- 08:19, 8 April 2024 Fire talk contribs marked Nicotinamide riboside for translation
- 08:19, 8 April 2024 Fire talk contribs limited languages for translatable page Nicotinamide riboside to Japanese
- 08:18, 8 April 2024 Fire talk contribs created page Category:Ribosides (Created page with "{{cat main|Riboside}} Category:Glycosides by glycone type Category:Ribose")
- 08:14, 8 April 2024 Fire talk contribs created page oxidoreductase activity, acting on diphenols and related substances as donors (Q21878) (wbeditentity-create:2|en: oxidoreductase activity, acting on diphenols and related substances as donors, Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.)
- 08:13, 8 April 2024 Fire talk contribs created page dihydronicotinamide riboside quinone reductase activity (Q21877) (wbeditentity-create:2|en: dihydronicotinamide riboside quinone reductase activity, Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.)
- 08:10, 8 April 2024 Fire talk contribs created page nicotinamide riboside transport (Q21876) (wbeditentity-create:2|en: nicotinamide riboside transport, The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.)
- 08:09, 8 April 2024 Fire talk contribs created page nicotinamide riboside transmembrane transporter activity (Q21875) (wbeditentity-create:2|en: nicotinamide riboside transmembrane transporter activity, Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.)
- 14:34, 7 April 2024 Fire talk contribs created page pyridine nucleoside biosynthetic process (Q21874) (wbeditentity-create:2|en: pyridine nucleoside biosynthetic process, The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose.)
- 14:33, 7 April 2024 Fire talk contribs created page nicotinamide riboside biosynthetic process (Q21873) (wbeditentity-create:2|en: nicotinamide riboside biosynthetic process, The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.)
- 14:30, 7 April 2024 Fire talk contribs created page nicotinamide riboside metabolic process (Q21872) (wbeditentity-create:2|en: nicotinamide riboside metabolic process, The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.)
- 14:27, 7 April 2024 Fire talk contribs created page pyridine nucleoside metabolic process (Q21871) (wbeditentity-create:2|en: pyridine nucleoside metabolic process, The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.)
- 14:27, 7 April 2024 Fire talk contribs created page pyridine nucleoside catabolic process (Q21870) (wbeditentity-create:2|en: pyridine nucleoside catabolic process, The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.)
- 14:26, 7 April 2024 Fire talk contribs created page nicotinamide riboside catabolic process (Q21869) (wbeditentity-create:2|en: nicotinamide riboside catabolic process, The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.)
- 14:24, 7 April 2024 Fire talk contribs created page N-ribosylnicotinamide (Q21868) (wbeditentity-create:2|en: N-ribosylnicotinamide, chemical compound)
- 14:21, 7 April 2024 Fire talk contribs created page Template:Chembox Explosive (Created page with "{{#if:{{{ShockSens|}}}{{{FrictionSens|}}}{{{DetonationV|}}}{{{ExplosiveV|}}}{{{REFactor|}}} |<!-- then: ----- HEADER ----- -->{{Chembox headerbar |header=Explosive data |ref={{{Explosive_ref|}}}<!-- ----- maintenance cats ----- -->|addMainCategories=<!-- ----- templatepar ----- -->|templatepar={{#invoke:TemplatePar |check |template=Template:Chembox Explosive |all= |opt= Explosive_ref= ShockSens= FrictionSens= DetonationV= REFactor= |cat=Pages using Chembox with unkno...")
- 14:20, 7 April 2024 Fire talk contribs created page Template:Chembox Structure (Created page with "{{#if:{{{CrystalStruct|}}}{{{SpaceGroup|}}}{{{PointGroup|}}}{{{LattConst_a|}}}{{{LattConst_b|}}}{{{LattConst_c|}}}{{{LattConst_alpha|}}}{{{LattConst_beta|}}}{{{LattConst_gamma|}}}{{{LattConst_Comment|}}}{{{UnitCellVolume|}}}{{{UnitCellFormulas|}}}{{{Coordination|}}}{{{MolShape|}}}{{{OrbitalHybridisation|}}}{{{Dipole|}}} |<!-- then: ----- HEADER ----- -->{{Chembox headerbar |header=Structure |ref={{{Structure_ref|}}}<!-- ----- maintenance cats ----- -->|addMainCategorie...")
- 14:20, 7 April 2024 Fire talk contribs created page Nicotinamide riboside (Created page with "{{Chembox | Name = | ImageFile = nicotinamide-beta-riboside.svg | ImageAlt = | ImageCaption = | ImageFile1 = Nicotinamideriboside.png | ImageAlt1 = | ImageCaption1 = | IUPACName = 3-Carbamoyl-1-(β-<small>D</small>-ribofuranosyl)pyridin-1-ium | SystematicName = 3-Carbamoyl-1-[(2''R'',3''R'',4''S'',5''R'')-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium | OtherNames = 1-(β-<small>D</small>-Ribofuranosyl)nicotinamide; ''N''-Ribosylnicotinamide |Section1={{Che...")
- 14:16, 7 April 2024 Fire talk contribs created page Niacinamide/ja (Redirected page to ニコチンアミド) Tag: New redirect
- 14:14, 7 April 2024 Fire talk contribs created page Niacinamide (Created page with "{{Short description|Dietary supplement and medication}} {{Infobox drug | image = Nicotinamid.svg | width = | alt = | image2 = Nicotinamide-from-xtal-2011-Mercury-3D-sf.png | width2 = | alt2 = | caption = <!-- Clinical data --> | pronounce = {{IPAc-en|ˌ|n|aɪ|ə|ˈ|s|ɪ|n|ə|m|aɪ|d}}, {{IPAc-en|ˌ|n|ɪ|k|ə|ˈ|t|ɪ|n|ə|m|aɪ|d}} | tradename = | Drugs.com...")