Main public logs

Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

• 20:22, 12 February 2024 Fire talk contribs created page methanol dehydrogenase activity (Q20869) (wbeditentity-create:2|en: methanol dehydrogenase activity, Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH.)
• 20:21, 12 February 2024 Fire talk contribs created page Translations:SGLT2 inhibitor/7/ja (Created page with "==副作用== {{Anchor|Adverse effects}} グリフロジンの副作用としては生殖器感染症が最も多いようである。臨床試験では、真菌感染症、尿路感染症、浸透圧利尿がグリフロジン投与患者で高かった。")
• 20:20, 12 February 2024 Fire talk contribs created page 4-methyloxaloacetate esterase activity (Q20868) (wbeditentity-create:2|en: 4-methyloxaloacetate esterase activity, Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H(2)O = H(+) + methanol + oxaloacetate.)
• 20:19, 12 February 2024 Fire talk contribs created page Translations:SGLT2 inhibitor/6/ja (Created page with "2つのレビューで、SGLT2阻害薬はアテローム性動脈硬化症の主要有害心血管イベント（MACE）患者に有益であると結論されている。そのうちの1つの研究では、MACEを心筋梗塞、脳卒中、心血管死の複合と定義した。")
• 20:16, 12 February 2024 Fire talk contribs created page methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity (Q20867) (wbeditentity-create:2|en: methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity, Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide.)
• 20:15, 12 February 2024 Fire talk contribs created page Translations:SGLT2 inhibitor/5/ja (Created page with "13の心血管アウトカム試験を含むメタアナリシスによると、SGLT-2阻害薬は、特に推算糸球体濾過量（eGFR）が60ml/分未満の被験者において、3点MACEのリスクを低下させるが、GLP-1受容体作動薬はeGFRが高い人ほど有益であった。同様に、SGLT-2阻害薬によるリス...")
• 20:13, 12 February 2024 Fire talk contribs created page pheophorbidase activity (Q20866) (wbeditentity-create:2|en: pheophorbidase activity, Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a)
• 20:13, 12 February 2024 Fire talk contribs created page Translations:SGLT2 inhibitor/4/ja (Created page with "SGLT-2阻害薬、GLP-1作動薬、およびDPP-4阻害薬を比較したシステマティックレビューとネットワークメタ解析では、SGLT2阻害薬の使用は、プラセボまたは無治療と比較して死亡の20％減少と関連していることが示された。別の系統的レビューでは、SGLT-2阻害薬が2型...")
• 20:10, 12 February 2024 Fire talk contribs created page juvenile-hormone esterase activity (Q20865) (wbeditentity-create:2|en: juvenile-hormone esterase activity, Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juveni)
• 20:08, 12 February 2024 Fire talk contribs created page Translations:SGLT2 inhibitor/3/ja (Created page with "==医薬用途== {{Anchor|Medical uses}} 2022年のADAの糖尿病診療標準では、SGLT2阻害薬は2型糖尿病のファーストライン薬物療法として（通常はメトホルミンと併用する）、特に慢性腎臓病、心血管疾患、心不全を有する患者に使用されている。")
• 19:56, 12 February 2024 Fire talk contribs created page hydrogen metabolic process (Q20864) (wbeditentity-create:2|en: hydrogen metabolic process, chemical reactions and pathways involving H2 (dihydrogen))
• 19:55, 12 February 2024 Fire talk contribs created page methane biosynthetic process from methanol and hydrogen (Q20863) (wbeditentity-create:2|en: methane biosynthetic process from methanol and hydrogen, The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen.)
• 19:53, 12 February 2024 Fire talk contribs created page Translations:SGLT2 inhibitor/2/ja (Created page with "'''SGLT2阻害薬'''は、'''グリフロジン'''または'''フロジン'''とも呼ばれ、腸管粘膜で同様の機能を果たすSGLT1阻害薬とは異なり、ネフロン（腎臓の機能単位）におけるナトリウム-グルコース輸送タンパク質を阻害する医薬品の一種である。この代謝作用の最たるものは、renal...")
• 19:48, 12 February 2024 Fire talk contribs created page response to methanol (Q20862) (wbeditentity-create:2|en: response to methanol, Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.)
• 19:47, 12 February 2024 Fire talk contribs created page SGLT2 inhibitor/ja (Created page with "SGLT2阻害剤")
• 19:47, 12 February 2024 Fire talk contribs created page cellular response to methanol (Q20861) (wbeditentity-create:2|en: cellular response to methanol, Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.)
• 19:46, 12 February 2024 Fire talk contribs created page Translations:SGLT2 inhibitor/1/ja (Created page with "{{Drug List/ja|state6=uncollapsed}} {{Pathnav|Medication/ja|Diabetes medication/ja|frame=1}} {| class="wikitable sortable" style="width:100%" |- !一般名 !先発名 !class="unsortable"| 日本 !創薬/開発 !備考 |- |イプラグリフロジン |[https://amn.astellas.jp/di/detail/sgl/index_sgl-25 スーグラ](Sugulat) ([https://amn.astellas.jp/common/pdfviewer.html/content/dam/jp/amn/jp/ja/di/doc/Pdfs/DocNo202211124_y.pdf PI]) ([https://amn.astellas.jp/common/pdfviewer.ht...")
• 19:46, 12 February 2024 Fire talk contribs created page Translations:SGLT2 inhibitor/Page display title/ja (Created page with "SGLT2阻害剤")
• 19:46, 12 February 2024 Fire talk contribs marked SGLT2 inhibitor for translation
• 19:46, 12 February 2024 Fire talk contribs limited languages for translatable page SGLT2 inhibitor to Japanese
• 19:44, 12 February 2024 Fire talk contribs created page Category:SGLT2 inhibitors (Created page with "{{Cat main|SGLT2 inhibitor}} {{Commons cat|SGLT2 inhibitors}} {{Sodium-glucose transporter modulators}} Category:Anti-diabetic drugs Category:Drugs acting on the cardiovascular system")
• 19:43, 12 February 2024 Fire talk contribs created page methanol catabolic process (Q20860) (wbeditentity-create:2|en: methanol catabolic process, The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.)
• 19:41, 12 February 2024 Fire talk contribs created page gliflozins (Q20859) (wbeditentity-create:2|en: gliflozins, class of pharmaceutical drugs)
• 19:40, 12 February 2024 Fire talk contribs created page Template:Sodium-glucose transporter modulators (Created page with "{{Navbox | name = Sodium-glucose transporter modulators | title = Sodium-glucose transporter modulators | state = {{{state<includeonly>|collapsed</includeonly>}}} | listclass = hlist | groupstyle = text-align:center; | group1 = {{abbrlink|SGLT1|Sodium-glucose transporter 1}} | list1 = * '''Inhibitors:''' Phloretin * Phlorizin * T-1095 * T-1095A | group2 = {{abbrlink|SGLT2|Sodium-glucose transporter 2}} | list2 =...")
• 19:40, 12 February 2024 Fire talk contribs created page SGLT2 inhibitor (Created page with "{{Drug List/ja|state6=uncollapsed}} {{Pathnav|Medication|Diabetes medication|frame=1}} {| class="wikitable sortable" style="width:100%" |- !一般名 !先発名 !class="unsortable"| 日本 !創薬/開発 !備考 |- |イプラグリフロジン |[https://amn.astellas.jp/di/detail/sgl/index_sgl-25 スーグラ](Sugulat) ([https://amn.astellas.jp/common/pdfviewer.html/content/dam/jp/amn/jp/ja/di/doc/Pdfs/DocNo202211124_y.pdf PI]) ([https://amn.astellas.jp/common/pdfviewer.html/con...")
• 19:24, 12 February 2024 Fire talk contribs created page Gliflozin/ja (Redirected page to SGLT2阻害剤) Tag: New redirect
• 19:23, 12 February 2024 Fire talk contribs created page Gliflozin (Redirected page to SGLT2 inhibitor) Tag: New redirect
• 19:21, 12 February 2024 Fire talk contribs created page methanol biosynthetic process (Q20858) (wbeditentity-create:2|en: methanol biosynthetic process, The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.)
• 16:57, 12 February 2024 Fire talk contribs created page methanogenesis, from methanol (Q20857) (wbeditentity-create:2|en: methanogenesis, from methanol, The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol.)
• 16:49, 12 February 2024 Fire talk contribs created page methanol metabolic process (Q20856) (wbeditentity-create:2|en: methanol metabolic process, The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.)
• 16:48, 12 February 2024 Fire talk contribs created page methanol (Q20855) (wbeditentity-create:2|en: methanol, chemical compound)
• 16:46, 12 February 2024 Fire talk contribs created page formaldehyde dismutase activity (Q20854) (wbeditentity-create:2|en: formaldehyde dismutase activity, Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.)
• 16:42, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/22/ja (Created page with "Category:Drugs developed by Eli Lilly and Company Category:GLP-1 receptor agonists Category:Peptide therapeutics")
• 16:42, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/21/ja (Created page with "{{Oral hypoglycemics and insulin analogs/ja|state=expanded}} {{Portal bar | Medicine}}")
• 16:42, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/20/ja (Created page with "== Further reading == * {{cite journal | vauthors = Scott LJ | title = Dulaglutide: A Review in Type 2 Diabetes | journal = Drugs | volume = 80 | issue = 2 | pages = 197–208 | date = February 2020 | pmid = 32002850 | doi = 10.1007/s40265-020-01260-9 | s2cid = 210954338 }} * {{cite journal | vauthors = Edwards KL, Minze MG | title = Dulaglutide: an evidence-based review of its potential in the treatment of type 2 diabetes | journal = Core Evidence | volume = 10 | pages...")
• 16:42, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/19/ja (Created page with "2020年、FDAはAWARD-11試験の結果に基づいて、3.0 mgと4.5 mgの2種類の高用量医薬品を承認した。")
• 16:41, 12 February 2024 Fire talk contribs created page oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor (Q20853) (wbeditentity-create:2|en: oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor, Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome.)
• 16:40, 12 February 2024 Fire talk contribs created page formate dehydrogenase (cytochrome-c-553) activity (Q20852) (wbeditentity-create:2|en: formate dehydrogenase (cytochrome-c-553) activity, Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2.)
• 16:32, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/18/ja (Created page with "米国食品医薬品局（FDA）はデュラグルチドをリスク評価と軽減戦略（REMS）付きで承認し、イーライリリー・アンド・カンパニーにトルリシティの承認を認めた。REMSは、膵炎のリスクと薬物に関連する甲状腺髄様癌の潜在的なリスクを医師に認識...")
• 16:30, 12 February 2024 Fire talk contribs created page luciferin monooxygenase activity (Q20851) (wbeditentity-create:2|en: luciferin monooxygenase activity, Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission)
• 16:29, 12 February 2024 Fire talk contribs created page Latia-luciferin monooxygenase (demethylating) activity (Q20850) (wbeditentity-create:2|en: Latia-luciferin monooxygenase (demethylating) activity, Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.)
• 16:28, 12 February 2024 Fire talk contribs created page oxalate decarboxylase activity (Q20849) (wbeditentity-create:2|en: oxalate decarboxylase activity, Catalysis of the reaction: H(+) + oxalate = CO(2) + formate.)
• 16:27, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/17/ja (Created page with "==歴史== {{Anchor|History}} デュラグルチドの安全性と有効性は、3,342人の2型糖尿病患者を対象とした6つの臨床試験で評価された。デュラグルチドを投与された被験者は、HbA1c値（ヘモグロビンA1cは血糖コントロールの指標）の低下により観察されるように、血糖コントロールの改善を認めた。")
• 16:26, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/16/ja (Created page with "==作用機序== {{Anchor|Mechanism of action}} デュラグルチドはグルカゴン様ペプチド1受容体に結合し、胃排出を遅らせ、膵β細胞からのインスリン分泌を増加させる。同時に、糖尿病患者ではグルカゴンが不適切に上昇することが知られているため、この化合物は膵臓のα細胞を阻害することにより、上昇したグルカゴンの分泌を抑える。GLP-1は通常、食事に反応...")
• 16:25, 12 February 2024 Fire talk contribs created page formyl-CoA transferase activity (Q20848) (wbeditentity-create:2|en: formyl-CoA transferase activity, Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.)
• 16:06, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/15/ja (Created page with "甲状腺髄様癌（MTC）の個人歴や家族歴のある人、あるいは多発性内分泌腫瘍2型に罹患している人は、これらの癌のリスクを高める可能性があるため、デュラグルチドを服用すべきではない。")
• 16:05, 12 February 2024 Fire talk contribs created page 2-hydroxymuconate-semialdehyde hydrolase activity (Q20847) (wbeditentity-create:2|en: 2-hydroxymuconate-semialdehyde hydrolase activity, Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate.)
• 16:01, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/14/ja (Created page with "==禁忌== {{Anchor|Contraindications}} 本剤は、有効成分または本剤の成分に対して過敏症のある被験者には禁忌である。")
• 15:59, 12 February 2024 Fire talk contribs created page S-formylglutathione hydrolase activity (Q20846) (wbeditentity-create:2|en: S-formylglutathione hydrolase activity, Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+).)
• 15:58, 12 February 2024 Fire talk contribs created page Translations:Dulaglutide/13/ja (Created page with "==副作用== {{Anchor|Side effects}} 最も一般的な副作用は、消化不良、食欲減退、吐き気、嘔吐、腹痛、下痢などの胃腸障害である。 重篤な副作用を経験する患者もいる： 急性膵炎（症状には持続性の激しい腹痛が含まれ、時に背中に放散し、嘔吐を伴う）...")