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Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 18:55, 6 February 2024 Fire talk contribs created page Template:Peacock inline (Created page with "{{ {{{|safesubst:}}}#invoke:Unsubst||date=__DATE__ |$B= <!-- {{Peacock inline}} begin -->{{Fix | subst = <includeonly>{{subst:</includeonly><includeonly>substcheck}}</includeonly> | link = Wikipedia:Manual of Style/Words to watch#Puffery | text = peacock prose | title = Unverified descriptions | date = {{{date|}}} | cat = Category:All articles with peacock terms | cat-date = Category:Articles with peacock terms }}<!-- {{Peacock inline}} end --> }}<noinclude...")
- 18:55, 6 February 2024 Fire talk contribs created page Template:Pharmaceutical companies of the United States (Created page with "{{Navbox | name = Pharmaceutical companies of the United States | title = {{flagicon|United States}} Pharmaceutical companies of the United States | bodyclass = hlist | state = {{{state<includeonly>|autocollapse</includeonly>}}} | group1 = Current | list1 = * Abbott Laboratories * AbbVie Inc. * Acorda Therapeutics * Advaxis * Alcon * Alexion * Alnylam...")
- 18:54, 6 February 2024 Fire talk contribs created page Eli Lilly and Company (Created page with "{{Short description|American pharmaceutical company}} {{other uses|Eli Lilly (disambiguation)}} {{Use dmy dates|date=July 2022}} {{Infobox company | name = Eli Lilly and Company | logo = Eli Lilly and Company.svg | type = Public | traded_as = {{unbulleted list|{{NYSE|LLY}}|S&P 100 component|S&P 500 component}} | ISIN = {{ISIN|sl=n|pl=y|US5324571083}} | founder = Eli Lilly | key_people = David A. Ricks (Chair, President (co...")
- 18:04, 6 February 2024 Fire talk contribs created page cresol metabolic process (Q20574) (wbeditentity-create:2|en: cresol metabolic process, The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as in)
- 18:02, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/25/ja (Created page with " ")
- 18:02, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/24/ja (Created page with "{{Oral hypoglycemics and insulin analogs/ja}}")
- 18:02, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/23/ja (Created page with "==適応外使用と娯楽的使用== {{Anchor|Off-label and recreational use}} GLP-1アゴニストは、医学的な用途のほかに、インフルエンサーや有名人によって広まった美容的な減量のために、多くの人々によって求められている。グレーマーケットの販売者は、GLP-1作動薬であると主張する無許可の製品をオンラインで...")
- 18:00, 6 February 2024 Fire talk contribs created page toluenes (Q20573) (wbeditentity-create:2|en: toluenes, class of chemical compounds)
- 17:59, 6 February 2024 Fire talk contribs created page toluene-containing compound metabolic process (Q20572) (wbeditentity-create:2|en: toluene-containing compound metabolic process, The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives.)
- 17:58, 6 February 2024 Fire talk contribs created page toluene-containing compound catabolic process (Q20571) (wbeditentity-create:2|en: toluene-containing compound catabolic process, The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.)
- 17:57, 6 February 2024 Fire talk contribs created page cresol catabolic process (Q20570) (wbeditentity-create:2|en: cresol catabolic process, The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, s)
- 17:56, 6 February 2024 Fire talk contribs created page cresol (Q20569) (wbeditentity-create:2|en: cresol, monomethylphenols and their derivatives formed by substitution on the ring with substituents other than -OH)
- 17:37, 6 February 2024 Fire talk contribs created page Alkylphenol (Q20568) (wbeditentity-create:2|en: Alkylphenol, family of organic compounds)
- 17:37, 6 February 2024 Fire talk contribs created page cresols (Q20567) (wbeditentity-create:2|en: cresols, group of chemical compounds)
- 17:35, 6 February 2024 Fire talk contribs created page para-cresol (Q20566) (wbeditentity-create:2|en: para-cresol, chemical compound)
- 17:13, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/22/ja (Created page with "GLP-1アゴニストは、2型糖尿病を治療するためのインスリンとの併用薬として利用可能であるが、これらの併用処方がインスリンとGLP-1アゴニストを別々に投与するよりも利点があるかどうかは不明である。実験的な処方であるカグリリンド/セマグルテスは、さらなる体重減少のためにdual amylin and calcitonin receptor agonist/ja|二重アミ...")
- 17:12, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/21/ja (Created page with "==複合および複数の標的薬=== {{Anchor|Combination and multiple target drugs}} {{see also/ja|GLP1 poly-agonist peptides/ja}} ティルゼパチドのようないくつかのGLP-1アゴニストは、GIP受容体および/またはグルカゴン受容体のアゴニストでもある。これらの付加的な標的は、薬物によって引き起こされる体重減少の量を改善すること...")
- 17:04, 6 February 2024 Fire talk contribs created page thiamine import across plasma membrane (Q20565) (wbeditentity-create:2|en: thiamine import across plasma membrane, The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol.)
- 16:57, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/20/ja (Created page with "==承認済み== {{Anchor|Approved}} *エクセナチド(商品名バイエッタ(Byetta)、ビデュリオン(Bydureon)、アストラゼネカ社製)、2005年/2012年承認。 *リラグルチド(糖尿病治療薬ビクトーザ(Victoza)、肥満治療薬サクセンダ(Saxenda)、ノボ・ノルディスク社製)、2010年承認 *アルビグルチド(タンゼウム(T...")
- 16:51, 6 February 2024 Fire talk contribs created page thiaminium carboxylate betaine (Q20564) (wbeditentity-create:2|en: thiaminium carboxylate betaine, chemical compound)
- 16:49, 6 February 2024 Fire talk contribs created page thiamine oxidase activity (Q20563) (wbeditentity-create:2|en: thiamine oxidase activity, Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.)
- 16:45, 6 February 2024 Fire talk contribs created page ABC-type thiamine transporter activity (Q20562) (wbeditentity-create:2|en: ABC-type thiamine transporter activity, Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine(out) = ADP + H(+) + phosphate + thiamine(in).)
- 16:39, 6 February 2024 Fire talk contribs created page thiamine-containing compound biosynthetic process (Q20561) (wbeditentity-create:2|en: thiamine-containing compound biosynthetic process, The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds.)
- 16:36, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/19/ja (Created page with "==コスト== {{Anchor|Cost}} GLP-1作動薬は2型糖尿病の他の治療薬よりも高価である。台湾の2型糖尿病患者において、GLP-1作動薬と長時間作用型インスリンの費用対効果を比較した研究がある。CVDを有する患者において、GLP-1作動薬は心血管事故が少ないため、費用を節約できると推定された。CVDのない患者では、1QALYあたりのコストは9,093ド...")
- 16:33, 6 February 2024 Fire talk contribs created page thiamine diphosphate catabolic process (Q20560) (wbeditentity-create:2|en: thiamine diphosphate catabolic process, The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.)
- 16:32, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/18/ja (Created page with "==薬物送達== {{Anchor|Drug delivery}} ネイティブGLP-1はペプチドホルモンであり、酵素ジペプチジルペプチダーゼ-4によって速やかに消去されるため、半減期は2分である。その結果、さまざまなGLP-1作動薬が半減期を延長するためにさまざまな方法で改良され、その結果、1日に複数回、毎日、毎週、あるいはそれ以下の頻度で...")
- 16:29, 6 February 2024 Fire talk contribs created page mitochondrial thiamine pyrophosphate transmembrane transport (Q20559) (wbeditentity-create:2|en: mitochondrial thiamine pyrophosphate transmembrane transport, The directed movement of thiamine pyrophosphate from one side of a membrane to the other into, out of or within a mitochondrion.)
- 16:27, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/17/ja (Created page with "症例報告によると、グルカゴン様ペプチド1(GLP-1)受容体作動薬を服用している患者は、胃排出の遅延により、麻酔中の誤嚥リスクが高まる可能性がある。2023年、米国麻酔科学会は、GLP-1作動薬を処置・手術の当日または1週間前に保持することを提案した。")
- 16:27, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/16/ja (Created page with "インスリンと同様に、GLP-1アゴニストも網膜症を引き起こしたり悪化させたりすることがあるが、これは直接的な影響というよりも、グルコースの急激な低下によって間接的に引き起こされると考えられている。患者の中には抗薬物抗体を発症する者がいるが、これは他のGLP-1作動薬よりもエキセナチドで...")
- 16:26, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/15/ja (Created page with "ヒトを対象とした臨床試験およびメタアナリシスでは、本剤と膵炎または膵がんとの関連は認められていない。しかしながら、市販後の報告で膵炎の症例報告がいくつか出ており、米国臨床内分泌医会は膵炎の既往歴のある人には注意を勧めている。急性膵炎が発生した場合は...")
- 16:24, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/14/ja (Created page with "==副作用== {{Anchor|Adverse effects}} GLP-1作動薬の最も一般的な副作用は消化器系である。これらの副作用は最大耐容量を制限し、漸進的な用量漸増を必要とする。吐き気はGLP-1作動薬の血清濃度に直接関係しており、短時間作用型GLP-1作動薬を使用している人では4分の3まで、より一般的に報告されているが、長時間作用型作動薬を使用してい...")
- 16:21, 6 February 2024 Fire talk contribs created page thiamine pyrophosphate transmembrane transporter activity (Q20558) (wbeditentity-create:2|en: thiamine pyrophosphate transmembrane transporter activity, Enables the directed movement of thiamine pyrophosphate into, out of or within a cell, or between cells.)
- 16:20, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/13/ja (Created page with "===報酬系障害=== GLP-1作動薬は、薬理学的治療の選択肢がほとんどない薬物使用障害に対して開発中である。GLP-1作動薬は、ヒト以外の動物では薬物やアルコールの自己摂取量を減少させるが、ヒトではこの効果は証明されていない。この中毒軽減作用の機序は不明である。GLP-1作動薬は、最も一般的な摂食障害であるbinge eating disord...")
- 16:18, 6 February 2024 Fire talk contribs created page thiamine pyrophosphate transmembrane transport (Q20557) (wbeditentity-create:2|en: thiamine pyrophosphate transmembrane transport, The directed movement of thiamine pyrophosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.)
- 16:16, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/12/ja (Created page with "===うつ病=== GLP-1作動薬は、抗うつ薬および神経保護薬としての効果を示している。また、第二世代抗精神病薬の代謝上の悪影響に対する治療薬としても使用できる。")
- 12:59, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/11/ja (Created page with "===多嚢胞性卵巣症候群=== GLP-1作動薬は、単独またはメトホルミンとの併用で、多嚢胞性卵巣症候群の治療薬として推奨されている。併用療法は、体重、インスリン感受性、アンドロゲン亢進症、および月経周期不順の改善においてより高い有効性を示している。この使用法は適応外...")
- 12:56, 6 February 2024 Fire talk contribs created page thiamine pyrophosphate binding (Q20556) (wbeditentity-create:2|en: thiamine pyrophosphate binding, Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.)
- 12:55, 6 February 2024 Fire talk contribs created page Thiamin Diphosphate (Q20555) (wbeditentity-create:2|en: Thiamin Diphosphate, chemical compound)
- 12:52, 6 February 2024 Fire talk contribs created page thiamine diphosphate metabolic process (Q20554) (wbeditentity-create:2|en: thiamine diphosphate metabolic process, The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.)
- 12:51, 6 February 2024 Fire talk contribs created page thiamine diphosphate biosynthetic process (Q20553) (wbeditentity-create:2|en: thiamine diphosphate biosynthetic process, The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.)
- 12:49, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/10/ja (Created page with "===非アルコール性脂肪性肝疾患=== GLP-1作動薬は、非アルコール性脂肪性肝疾患(NAFLD)の治療薬として研究されている。 2023年のシステマティックレビューによれば、GLP-1作動薬は現在使用されているピオグリタゾンやビタミンEと少なくとも同等の効果があり、脂肪症、バルーン壊死、小葉の炎症...")
- 12:45, 6 February 2024 Fire talk contribs created page thiamin-triphosphatase activity (Q20552) (wbeditentity-create:2|en: thiamin-triphosphatase activity, Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate.)
- 12:44, 6 February 2024 Fire talk contribs created page thiamine(1+) triphosphate(4-) (Q20551) (wbeditentity-create:2|en: thiamine(1+) triphosphate(4-), chemical compound)
- 12:42, 6 February 2024 Fire talk contribs created page thiamine-diphosphate kinase activity (Q20550) (wbeditentity-create:2|en: thiamine-diphosphate kinase activity, Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate.)
- 12:39, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/9/ja (Created page with "===肥満症=== GLP-1作動薬は、BMIが30を超えるか、またはBMIが27を超え、少なくとも1つの体重関連合併症を有する患者において、生活習慣介入(カロリー制限および運動)の上乗せ療法として推奨されている。セマグルチドなどの一部のGLP-1作動薬は、他の減量薬よりも効果が高いが、それでも体重減少を引き起こすという点ではbariatric surg...")
- 12:36, 6 February 2024 Fire talk contribs created page thiamine-diphosphatase activity (Q20549) (wbeditentity-create:2|en: thiamine-diphosphatase activity, Catalysis of the reaction: TDP + H2O = TMP + phosphate.)
- 12:33, 6 February 2024 Fire talk contribs created page Translations:GLP-1 receptor agonist/8/ja (Created page with "===心血管疾患=== GLP-1作動薬は、肥満の治療に用いると心臓保護作用を示す。")
- 12:32, 6 February 2024 Fire talk contribs created page acid phosphatase activity (Q20548) (wbeditentity-create:2|en: acid phosphatase activity, Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.)
- 12:30, 6 February 2024 Fire talk contribs created page thiamine phosphate phosphatase activity (Q20547) (wbeditentity-create:2|en: thiamine phosphate phosphatase activity, Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate.)
- 12:28, 6 February 2024 Fire talk contribs created page thiamine kinase activity (Q20546) (wbeditentity-create:2|en: thiamine kinase activity, Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate.)