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Combined display of all available logs of Azupedia. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 21:36, 20 February 2024 Fire talk contribs limited languages for translatable page Vitamin B3 to Japanese
- 21:32, 20 February 2024 Fire talk contribs created page Vitamin B3 (Created page with "{{Short description|Class of chemically related vitamers}} {{DISPLAYTITLE:Vitamin B<sub>3</sub>}} {{Pathnav|Dietary supplement|Vitamin|frame=1}} {{Infobox drug class | Name = Vitamin B<sub>3</sub> | Image = Nicotinamid.svg | Alt = | Caption = Structure of nicotinamide, one of the vitamers of vitamin B<sub>3</sub> | Use = Vitamin B<sub>3</sub> deficiency | Biological_target = enzyme cofactor | ATC_prefix...")
- 21:19, 20 February 2024 Fire talk contribs created page Vitamin B2/ja (Redirected page to リボフラビン) Tag: New redirect
- 21:18, 20 February 2024 Fire talk contribs created page Vitamin B1/ja (Redirected page to チアミン) Tag: New redirect
- 21:18, 20 February 2024 Fire talk contribs created page Vitamin B2 (Redirected page to Riboflavin) Tag: New redirect
- 21:16, 20 February 2024 Fire talk contribs created page B vitamin (Redirected page to B vitamins) Tag: New redirect
- 21:16, 20 February 2024 Fire talk contribs created page B vitamin/ja (Redirected page to ビタミンB群) Tag: New redirect
- 21:15, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/11/ja (Created page with "イプラグリフロジンは、米国、欧州などでも2型糖尿病治療薬として開発されており、メトホルミンとの併用で3つの第II相試験が終了していた。これはその後中止された。")
- 21:14, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/10/ja (Created page with "しかし、イプラグリフロジンは現在、長期的(3年以上)に使用した場合の安全性を確認するための観察症例対照臨床試験中である。この試験の終了予定は2018年10月である。 * 2016年10月18日:アステラス製薬、2型糖尿病を対象とした国内臨床試験を2016年10月に先行して完了 * 2016年9月7日:アステラス製薬、日本で1型糖尿病を対象とした第III相臨床試験(...")
- 21:13, 20 February 2024 Fire talk contribs created page Translations:Pantothenic acid/32/ja (Created page with "{{DEFAULTSORT:Pantothenic Acid}} Category:Carboxamides Category:B vitamins Category:Alcohols Category:Carboxylic acids")
- 21:13, 20 February 2024 Fire talk contribs created page Translations:Pantothenic acid/31/ja (Created page with "{{Vitamins/ja}} {{Dietary supplement/ja}} {{Metabolism of vitamins, coenzymes, and cofactors/ja}} {{Preparations for treatment of wounds and ulcers/ja}} {{Cholinergics/ja}}")
- 21:13, 20 February 2024 Fire talk contribs created page Translations:Pantothenic acid/30/ja (Created page with "パントテン酸の必須性は、1933年にロジャー・J・ウィリアムズによって酵母の成長に必要であることを示すことによって発見された。その3年後、ElvehjemとJukesは、それがニワトリの成長と抗皮膚炎因子であることを証明した。ウィリアムズはこの化合物を「パントテン酸」と命名し、ギリシャ語の「パントテン(pantothen)」に由来する...")
- 21:12, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/9/ja (Created page with "プラセボ対照二重盲検試験が韓国の18ヵ所と台湾の12ヵ所で行われた。対象は20歳以上で2型糖尿病を12週間以上患っている患者であった。8週間の休薬期間を設け、メトホルミン以外の薬物をすべて除去した。患者は50mgのイプラグリフロジンとプラセボのいずれかを投与された。薬物は物理的な形はすべて同じであった。患者はメトホルミン以外の抗糖尿...")
- 21:10, 20 February 2024 Fire talk contribs created page Translations:Pantothenic acid/29/ja (Created page with "==歴史== {{Anchor|History}} {{Further/ja|Vitamin/ja#History}} ビタミンは1912年にポーランドの生化学者カシミール・フンクによって作られた造語で、彼は生命維持に不可欠な水溶性の微量栄養素の複合体を単離し、その全てがアミンであると推定した。後にこの推定が事実でないことが判明すると、名前から "e "が取り除かれ、"vitamin "となっ...")
- 21:09, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/8/ja (Created page with "==臨床試験== {{Anchor|Clinical trials}} イプラグリフロジンの有効性及び安全性は、国内におけるフェーズⅢの単剤投与試験及び他の血糖降下剤(6種類)との併用臨床試験において確認されている。")
- 21:08, 20 February 2024 Fire talk contribs created page Translations:Pantothenic acid/28/ja (Created page with "===工業的合成=== パントテン酸の工業的合成はイソブチルアルデヒドとホルムアルデヒドのアルドール縮合から始まる。得られたヒドロキシピバルデヒドはそのシアノヒドリン誘導体に変換され、これが環化されてラセミ体のパントラクトンが得られる。こ...")
- 21:06, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/7/ja (Created page with "イプラグリフロジンは、ナトリウム・グルコース共輸送体2(SGLT2)阻害薬(グリフロジン)である。これらの膜タンパク質は細胞表面に存在し、グルコースを細胞内に移行させる。SGLT2は、SGLTのサブタイプの1つであり、腎臓の近位尿細管におけるグルコースの再取り込みにおいて重要な役割を果たしている。イプラグリフロジンは...")
- 21:05, 20 February 2024 Fire talk contribs created page Translations:Pantothenic acid/27/ja (Created page with "==合成== {{Anchor|Synthesis}} ===生合成=== 細菌はアスパラギン酸とバリンというアミノ酸の前駆体からパントテン酸を合成する。アスパラギン酸はβ-アラニンに変換される。バリンのアミノ基はケト-部位で置換され、α-ケトイソバレレートが得られ、次いでメチル基の転移後にα-ケトパント酸が形成され、還...")
- 21:03, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/6/ja (Created page with "'''イプラグリフロジン'''('''Ipragliflozin'''、INN、商品名'''スーグラ''')は、2型糖尿病治療薬である。イプラグリフロジンはアステラス製薬と寿製薬が共同開発し、日本では2014年1月17日に、ロシアでは2019年5月22日に承認された。")
- 21:02, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/5/ja (Created page with "<!-- Chemical data --> | chemical_formula = | C=21 | H=21 | F=1 | O=5 | S=1 | SMILES =S1C(=CC2=C1C=CC=C2)CC=2C=C(C=CC2F)[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@H](O2)CO | StdInChI=1S/C21H21FO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1 COPY | StdInChIKey = AHFWIQIYAXSLBA-RQXATKFSSA-N }}")
- 21:02, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/4/ja (Created page with "<!-- Identifiers --> | CAS_number = 761423-87-4 | ATCvet = | ATC_prefix = A10 | ATC_suffix = BK05 | PubChem = 10453870 | ChemSpiderID = 8629286 | KEGG = D10196 | DrugBank = DB11698 | UNII = 3N2N8OOR7X | ChEMBL = 2018096 | synonyms = (1''S'')-1,5-anhydro-1-''C''-{3-[(1-benzothiophen-2-yl)methyl]-4-fluorophenyl}-<small>D</small>-glucitol")
- 21:02, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/3/ja (Created page with "<!-- Pharmacokinetic data --> | bioavailability = 90.2% | protein_bound = 94.6–96.5% | metabolism = UGT2B7/ja (major), UGT2B4/ja, 1A8, 1A9 (minor) | metabolites = | onset = | elimination_half-life = 14.97±4.58 hours | duration_of_action = | excretion = Urine/ja (67.9%), feces/ja (32.7%)")
- 21:01, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/2/ja (Created page with "<!-- Clinical data --> | tradename = Suglat | Drugs.com = | MedlinePlus = | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | pregnancy_AU_comment = | pregnancy_US = <!-- A / B / C / D / X / N --> | pregnancy_category = | legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> | legal_AU_comment = | legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_NZ = <!--Class A, B, C --> | legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM...")
- 21:01, 20 February 2024 FuzzyBot talk contribs created page Ipragliflozin/en (Updating to match new version of source page) Tags: Mobile edit Mobile web edit
- 21:01, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/1/ja (Created page with "{{Pathnav|Medication/ja|Diabetes medication/ja|SGLT2 inhibitor/ja|frame=1}} {{Infobox drug | drug_name = | IUPAC_name = (1''S'')-1,5-Anhydro-1-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-<small>D</small>-glucitol <!-- Chemspider ---> | image = Ipragliflozin structure.svg | width = 275 | image2 = Haworth projection of ipragliflozin.svg | width2 = 225 | caption = Haworth projection/ja (bottom)")
- 21:00, 20 February 2024 Fire talk contribs created page Ipragliflozin/ja (Created page with "イプラグリフロジン") Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 Fire talk contribs created page Translations:Ipragliflozin/Page display title/ja (Created page with "イプラグリフロジン")
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/19/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/18/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/17/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/16/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/15/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/14/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/13/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/12/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/11/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/10/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/9/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/8/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/7/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/6/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/5/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/4/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/3/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/2/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/1/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 FuzzyBot talk contribs created page Translations:Ipragliflozin/Page display title/en (Importing a new version from external source) Tags: Mobile edit Mobile web edit
- 21:00, 20 February 2024 Fire talk contribs marked Ipragliflozin for translation
- 21:00, 20 February 2024 Fire talk contribs limited languages for translatable page Ipragliflozin to Japanese
- 20:51, 20 February 2024 Fire talk contribs created page Translations:Pantothenic acid/26/ja (Created page with "反芻動物におけるパントテン酸の食事性要求量は確立されていない。反芻胃微生物によるパントテン酸の合成は、食餌量の20~30倍と思われる。去勢子牛の反芻胃におけるパントテン酸の正味微生物合成量は、1 日あたり消費される消化可能有機物 1kg あたり 2.2 mg/kg と推定されている。理論要求量の5~10倍のパントテン酸を補給しても、肥育...")