Insulin analog/ja: Difference between revisions

An '''insulin analog''' ([[American and British English spelling differences#-ogue, -og|also called]] an '''insulin analogue''') is any of several types of [[insulin (medication)|medical insulin]] that are altered forms of the hormone [[insulin]], different from any occurring in nature, but still available to the human body for performing the same action as human insulin in terms of [[Diabetes management#Glycemic control|controlling blood glucose levels in diabetes]]. Through [[genetic engineering]] of the underlying [[DNA]], the [[amino acid sequence]] of insulin can be changed to alter its [[ADME]] (absorption, distribution, metabolism, and excretion) characteristics.  Officially, the [[U.S. Food and Drug Administration]] (FDA) refers to these agents as '''insulin receptor ligands''' (because, like insulin itself, they are [[ligand (biochemistry)|ligands]] of the [[insulin receptor]]), although they are usually just referred to as insulin analogs or even (loosely but commonly) just insulin (without further specification).