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Collagen/ja: Difference between revisions

Collagen/ja
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Created page with "{| class="wikitable" |- |+'''コラーゲン遺伝子の遺伝子異常'''"
Created page with "上記の疾患に加えて、強皮症ではコラーゲンの過剰沈着が起こる。"
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|+'''コラーゲン遺伝子の遺伝子異常'''
|+'''コラーゲン遺伝子の遺伝子異常'''


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| '''タイプ''' || '''備考''' || '''遺伝子''' || '''[[Collagen disease/ja|障害]]'''
| '''Type''' || '''Notes''' || '''Gene(s)''' || '''[[Collagen disease|Disorders]]'''
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  | [[Type-I collagen|I]] || This is the most abundant collagen of the human body. It is present in [[scar]] tissue, the end product when tissue [[healing|heals]] by repair. It is found in [[tendon]]s, skin, artery walls, cornea, the [[endomysium]] surrounding muscle fibers, fibrocartilage, and the organic part of bones and teeth. || [[COL1A1]], [[COL1A2]] || [[Osteogenesis imperfecta]], [[Ehlers–Danlos syndrome]], [[infantile cortical hyperostosis]] a.k.a. Caffey's disease
  | [[Type-I collagen/ja|I]] || 人体に最も多く存在するコラーゲンである。組織が修復によって[[healing/ja|治療]]する際の最終産物である[[scar/ja|瘢痕]]組織に存在する。[[tendon/ja|腱]]、皮膚、動脈壁、角膜、筋線維を取り囲む[[endomysium/ja|内膜]]、線維軟骨、骨や歯の器質部分に存在する。 || [[COL1A1/ja]], [[COL1A2/ja]] || [[Osteogenesis imperfecta/ja]], [[Ehlers–Danlos syndrome/ja]], [[infantile cortical hyperostosis/ja]] 別名キャッフィー病
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  | [[Type-II collagen|II]] || [[Hyaline cartilage]], makes up 50% of all cartilage protein. [[Vitreous humour]] of the eye. || [[COL2A1]] || [[Collagenopathy, types II and XI]]
  | [[Type-II collagen/ja|II]] || [[Hyaline cartilage/ja|ヒアリン軟骨]]は軟骨タンパク質の50％を占める。眼球の[[vitreous humour/ja|硝子体液]] || [[COL2A1/ja]] || [[Collagenopathy, types II and XI/ja]]
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  | [[Type-III collagen|III]] || This is the collagen of [[granulation tissue]] and is produced quickly by young fibroblasts before the tougher type I collagen is synthesized. [[Reticular fiber]]. Also found in artery walls, skin, intestines and the uterus || [[COL3A1]] || [[Ehlers–Danlos syndrome]], [[Dupuytren's contracture]]
  | [[Type-III collagen/ja|III]] || これは[[granulation tissue/ja|肉芽組織]]のコラーゲンであり、より丈夫なI型コラーゲンが合成される前に、若い線維芽細胞によって速やかに産生される。[[reticular fiber/ja|網状線維]]。動脈壁、皮膚、腸、子宮にも見られる。 || [[COL3A1/ja]] || [[Ehlers–Danlos syndrome/ja]], [[Dupuytren's contracture/ja]]
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  | [[Type-IV collagen|IV]] || [[Basal lamina]]; [[eye lens]]. Also serves as part of the filtration system in [[capillaries]] and the [[Glomerulus (kidney)|glomeruli]] of [[nephron]] in the [[kidney]]. || [[Collagen, type IV, alpha 1|COL4A1]], [[COL4A2]], [[COL4A3]], [[COL4A4]], [[COL4A5]], [[COL4A6]] || [[Alport syndrome]], [[Goodpasture's syndrome]]
  | [[Type-IV collagen/ja|IV]] || [[Basal lamina/ja|基底膜]]、[[eye lens/ja|眼球の水晶体]]。また、[[capillaries/ja|毛細血管]]および[[kidney/ja|腎臓]]の[[nephron/ja|ネフロン]]の[[Glomerulus (kidney)/ja|糸球体]]の濾過システムの一部としても機能する。 || [[Collagen, type IV, alpha 1/ja|COL4A1]], [[COL4A2/ja]], [[COL4A3/ja]], [[COL4A4/ja]], [[COL4A5/ja]], [[COL4A6/ja]] || [[Alport syndrome/ja]], [[Goodpasture's syndrome/ja]]
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  | V || Most interstitial tissue, assoc. with type I, associated with [[placenta]] || [[COL5A1]], [[COL5A2]], [[COL5A3]] || [[Ehlers–Danlos syndrome]] (classical)
  | V || ほとんどの間質組織は、I型と関連している。 [[placenta/ja]] || [[COL5A1/ja]], [[COL5A2/ja]], [[COL5A3/ja]] || [[Ehlers–Danlos syndrome/ja]] (classical)
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  | VI || Most interstitial tissue, assoc. with type I || [[COL6A1]], [[COL6A2]], [[COL6A3]], [[COL6A5]] || [[Ulrich myopathy]], [[Bethlem myopathy]], [[atopic dermatitis]]
  | VI || ほとんどの間質組織は、I型と関連している。 || [[COL6A1/ja]], [[COL6A2/ja]], [[COL6A3/ja]], [[COL6A5/ja]] || [[Ulrich myopathy/ja]], [[Bethlem myopathy/ja]], [[atopic dermatitis/aj]]
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  | VII || Forms [[anchoring fibril]]s in [[dermoepidermal junction]]s || [[COL7A1]] || [[Epidermolysis bullosa dystrophica]]
  | VII || [[dermoepidermal junction/ja|真皮表皮接合部]]で[[anchoring fibril/ja|アンカリング線維]]を形成する。 || [[COL7A1/ja]] || [[Epidermolysis bullosa dystrophica/ja]]
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  | VIII || Some [[endothelium|endothelial]] cells || [[COL8A1]], [[COL8A2]] || [[Posterior polymorphous corneal dystrophy 2]]
  | VIII || いくつかの[[endothelium/ja内皮]]細胞がある。 || [[COL8A1/ja]], [[COL8A2/ja]] || [[Posterior polymorphous corneal dystrophy 2/ja]]
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  | IX || [[FACIT collagen]], cartilage, assoc. with type II and XI fibrils || [[COL9A1]], [[COL9A2]], [[COL9A3]] || [[EDM2]] and [[EDM3]]
  | IX || [[FACIT collagen/ja|FACITコラーゲン]], 軟骨、II型およびXI型線維に関連する。 || [[COL9A1/ja]], [[COL9A2/ja]], [[COL9A3/ja]] || [[EDM2/ja]]と[[EDM3/ja]]
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  | X || [[Hypertrophic]] and [[Mineralization (biology)|mineralizing]] cartilage || [[COL10A1]] || [[Schmid metaphyseal dysplasia]]
  | X || [[Hypertrophic/ja|肥大型]]と[[Mineralization (biology)/ja|石化]]軟骨 || [[COL10A1/ja]] || [[Schmid metaphyseal dysplasia/ja]]
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  | XI || Cartilage || [[COL11A1]], [[COL11A2]] || [[Collagenopathy, types II and XI]]
  | XI || 軟骨 || [[COL11A1/ja]], [[COL11A2/ja]] || [[Collagenopathy, types II and XI/ja]]
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  | XII || [[FACIT collagen]], interacts with type I containing fibrils, [[decorin]] and glycosaminoglycans || [[COL12A1]] || –
  | XII || [[FACIT collagen/ja|FACITコラーゲン]], フィブリル、[[decorin/ja|デコリン]]およびグリコサミノグリカンを含むI型と相互作用する || [[COL12A1/ja]] || –
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  | XIII || Transmembrane collagen, interacts with integrin a1b1, [[fibronectin]] and components of basement membranes like [[nidogen]] and [[perlecan]]. || [[COL13A1]] || –
  | XIII || 膜貫通型コラーゲンで、インテグリンa1b1、[[fibronectin/ja|フィブロネクチン]]、および[[didogen/ja|ニドゲン]]や[[perlecan/ja|ペルレカン]]のような基底膜の成分と相互作用する。 || [[COL13A1/ja]] || –
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  | XIV|| [[FACIT collagen]], also known as undulin || [[COL14A1]] || –
  | XIV|| [[FACIT collagen/ja|FACITコラーゲン]], 別名ウンドゥリン || [[COL14A1/ja]] || –
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  | XV || – || [[COL15A1]] || –
  | XV || – || [[COL15A1/ja]] || –
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  | XVI || [[FACIT collagen]] || [[COL16A1]] || –
  | XVI || [[FACIT collagen/ja|FACITコラーゲン]] || [[COL16A1/ja]] || –
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  | [[Collagen XVII|XVII]] || Transmembrane collagen, also known as BP180, a 180 kDa protein || [[COL17A1]] || [[Bullous pemphigoid]] and certain forms of junctional [[epidermolysis bullosa]]
  | [[Collagen XVII/ja|XVII]] || Transmembrane collagen, also known as BP180, a 180 kDa protein || [[COL17A1/ja]] || [[Bullous pemphigoid/ja]]および接合型[[epidermolysis bullosa/ja|表皮水疱症]]のある種の形態である。
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  | [[Type XVIII collagen|XVIII]] || Source of [[endostatin]] || [[COL18A1]] || –
  | [[Type XVIII collagen/ja|XVIII]] || [[endostatin/ja|エンドスタチン]]の生成源である。 || [[COL18A1/ja]] || –
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  | XIX || [[FACIT collagen]] || [[COL19A1]] || –
  | XIX || [[FACIT collagen/ja|FACITコラーゲン]] || [[COL19A1/ja]] || –
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  | XX || – || [[COL20A1]] || –
  | XX || – || [[COL20A1/ja]] || –
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  | XXI || [[FACIT collagen]] || [[COL21A1]] || –
  | XXI || [[FACIT collagen/ja|FACITコラーゲン]] || [[COL21A1/ja]] || –
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  | XXII || [[FACIT collagen]] || [[COL22A1]] || –
  | XXII || [[FACIT collagen/ja|FACITコラーゲン]] || [[COL22A1/ja]] || –
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  | [[Collagen, type XXIII, alpha 1|XXIII]] || MACIT collagen || [[COL23A1]] || –
  | [[Collagen, type XXIII, alpha 1/ja|XXIII]] || MACITコラーゲン || [[COL23A1/ja]] || –
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  | XXIV || – || [[COL24A1]] || –
  | XXIV || – || [[COL24A1/ja]] || –
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  | XXV || – || [[COL25A1]] || –
  | XXV || – || [[COL25A1/ja]] || –
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  | XXVI || – || [[EMID2]] || –
  | XXVI || – || [[EMID2/ja]] || –
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  | XXVII || – || [[COL27A1]] || –
  | XXVII || – || [[COL27A1/ja]] || –
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  | XXVIII || – || [[COL28A1]] || –
  | XXVIII || – || [[COL28A1/ja]] || –
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  | XXIX || Epidermal collagen || [[COL29A1]] || Atopic dermatitis
  | XXIX || 表皮コラーゲン || [[COL29A1/ja]] || アトピー性皮膚炎
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上記の疾患に加えて、[[scleroderma/ja|強皮症]]ではコラーゲンの過剰沈着が起こる。
In addition to the above-mentioned disorders, excessive deposition of collagen occurs in [[scleroderma]].
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Retrieved from "https://wiki.tiffa.net/wiki/Collagen/ja"