Translations:Riboflavin/17/ja: Difference between revisions

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Message definition (Riboflavin)
===Industrial synthesis===
[[File:Micrococcus riboflavin.jpg|thumb|Cultures of ''Micrococcus luteus'' growing on pyridine (left) and succinic acid (right). The pyridine culture has turned yellow from the accumulation of riboflavin.]]
The industrial-scale production of riboflavin uses various microorganisms, including [[Mold (fungus)|filamentous fungi]] such as ''[[Ashbya gossypii]]'', ''[[Candida famata]]'' and ''Candida flaveri'',  as well as the [[bacteria]] ''[[Corynebacterium]] ammoniagenes'' and ''[[Bacillus subtilis]]''. ''B. subtilis'' that has been genetically modified to both increase the production of riboflavin and to introduce an antibiotic ([[ampicillin]]) resistance marker, is employed at a commercial scale to produce riboflavin for [[animal feed|feed]] and food fortification. By 2012, over 4,000 tonnes per annum were produced by such fermentation processes.

工業合成

ピリジン（左）とコハク酸（右）で培養したMicrococcus luteusの培養液。ピリジン培養液はリボフラビンの蓄積により黄色に変色している。

リボフラビンの工業的生産には、Ashbya gossypii、Candida famata、Candida flaveriなどの糸状菌や、細菌のCorynebacterium ammoniagenes、枯草菌などを含む様々な微生物が用いられる。リボフラビンの生産量を増やし、抗生物質（アンピシリン）耐性マーカーを導入するために遺伝子組み換えされた枯草菌は、飼料や食品強化のためのリボフラビン生産に商業規模で使用されている。2012年までに、このような発酵プロセスによって年間4,000トン以上が生産された。

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