Translations:Sporulation in Bacillus subtilis/6/ja
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以下の表において、'アクチベーター'とは、最終的に胞子形成の開始をもたらす遺伝子/タンパク質を指し、'リプレッサー'とは、この胞子形成の開始を阻害するものを指す。
アクティベーター | レギュレーション | リプレッサー | レギュレーション |
---|---|---|---|
KinA | Transfers phosphate to the Spo0F | Sda | Blocks autophosphorylation of KinA |
KinB | Transfers phosphate to the Spo0F | KipI | Blocks autophosphorylation of KinA |
Spo0A | Activates several key sporulation-specific genes | Spo0A | Negatively controls transcription of abrB |
Spo0H (σH) | Activates phrE gene | ComA | Activates competence |
Spo0B | Phosphotransferase initiation | SinR | Negative regulation of kinB |
Spo0F | Phosphotransferase initiation | RapA, RapB, RapE, and RapH | Dephosphorylation of Spo0F~P |
ComA | Activates phrA | Spo0E, YisI, and YnzD | Dephosphorylation of Spo0A~P |
SinI | Antagonist of SinR | GTP-bound CodY | Inhibits rapA-phrA |
KipA | Inhibits kipI gene | AbrB | Encodes a repressor of spo0H |
PhrA | Suppresses dephosphorylation activity of RapA | Hpr | Overexpression inhibits sporulation |
PhrE | Inhibits RapE | DnaA | Over expression of Sda |
PhrH | Inhibits RapH |