Translations:Inulin/5/en

Inulin was discovered in 1804 by German scientist Valentin Rose. He found "a peculiar substance" from Inula helenium roots by boiling-water extraction. In the 1920s, J. Irvine used chemical methods such as methylation to study the molecular structure of inulin, and he designed the isolation method for this new anhydrofructose. During studies of renal tubules in the 1930s, researchers searched for a substance that could serve as a biomarker that is not reabsorbed or secreted after introduction into tubules. A. N. Richards introduced inulin because of its high molecular weight and its resistance to enzymes. Inulin is used to determine glomerular filtration rate of the kidneys.