Translations:Cytochrome P450/7/en

Microsomal P450 systems

in which electrons are transferred from NADPH via cytochrome P450 reductase (variously CPR, POR, or CYPOR). Cytochrome b₅ (cyb₅) can also contribute reducing power to this system after being reduced by cytochrome b₅ reductase (CYB₅R).

Mitochondrial P450 systems

which employ adrenodoxin reductase and adrenodoxin to transfer electrons from NADPH to P450.

Bacterial P450 systems

which employ a ferredoxin reductase and a ferredoxin to transfer electrons to P450.

CYB₅R/cyb₅/P450 systems

in which both electrons required by the CYP come from cytochrome b₅.

FMN/Fd/P450 systems

originally found in Rhodococcus species, in which a FMN-domain-containing reductase is fused to the CYP.

P450 only systems

which do not require external reducing power. Notable ones include thromboxane synthase (CYP5), prostacyclin synthase (CYP8), and CYP74A (allene oxide synthase).