Nifedipine: Difference between revisions

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===Other===

[[Raynaud's phenomenon]] is often treated with nifedipine. A 2005 meta-analysis showed modest benefits (33% decrease in attack severity, 2.8-5 reduction in absolute number of attacks per week); it does conclude that most included studies used low doses of nifedipine.<ref>{{cite journal | vauthors = Thompson AE, Pope JE | title = Calcium channel blockers for primary Raynaud's phenomenon: a meta-analysis | journal = Rheumatology | volume = 44 | issue = 2 | pages = 145–50 | date = February 2005 | pmid = 15546967 | doi = 10.1093/rheumatology/keh390 | doi-access = free }}</ref>

[[Raynaud's phenomenon]] is often treated with nifedipine. A 2005 meta-analysis showed modest benefits (33% decrease in attack severity, 2.8-5 reduction in absolute number of attacks per week); it does conclude that most included studies used low doses of nifedipine.

[[Topical]] nifedipine has been shown to be as effective as topical nitrates for [[anal fissure]]s.<ref name="pmid12794583">{{cite journal | vauthors = Ezri T, Susmallian S | title = Topical nifedipine vs. topical glyceryl trinitrate for treatment of chronic anal fissure | journal = Diseases of the Colon and Rectum | volume = 46 | issue = 6 | pages = 805–8 | date = June 2003 | pmid = 12794583 | doi = 10.1007/s10350-004-6660-8 | s2cid = 24717470 }}</ref>

[[Topical]] nifedipine has been shown to be as effective as topical nitrates for [[anal fissure]]s.

Nifedipine is also used in high-altitude medicine to treat [[high altitude pulmonary edema]].<ref name="eMedicine">{{cite web| url= http://www.emedicine.com/med/topic1956.htm| title= Pulmonary Edema, High-Altitude| author1= Ali, Mir Omar| author2= Qazi, Samia| name-list-style= amp| date= 19 September 2007| publisher= eMedicine| access-date= 25 November 2007| url-status= live| archive-url= https://web.archive.org/web/20071116141543/http://www.emedicine.com/med/topic1956.htm| archive-date= 16 November 2007}}</ref>

Nifedipine is also used in high-altitude medicine to treat [[high altitude pulmonary edema]].

Nifedipine is one of the main choices for the treatment of [[Prinzmetal angina]] due to its vasodilating effects on the coronary arteries.~~<ref name=AHFS2015/>~~

Nifedipine is one of the main choices for the treatment of [[Prinzmetal angina]] due to its vasodilating effects on the coronary arteries.

Other uses include painful spasms of the [[esophagus]] such as from [[cancer]] or [[tetanus]].{{medcn|date=January 2020}} It is also used for the small subset of people with [[pulmonary hypertension]].~~{{medcn|date=January 2020}}~~

Other uses include painful spasms of the [[esophagus]] such as from [[cancer]] or [[tetanus]].{{medcn|date=January 2020}} It is also used for the small subset of people with [[pulmonary hypertension]].

Finally, nifedipine can be used in the treatment of renal calculi, which are commonly referred to as [[kidney stones]]. Studies have indicated that it helps to relieve renal colic. However, alpha blockers (such as [[tamsulosin]]) have been described as being significantly better.<ref>{{cite journal | vauthors = Bos D, Kapoor A | title = Update on medical expulsive therapy for distal ureteral stones: Beyond alpha-blockers | journal = Canadian Urological Association Journal | volume = 8 | issue = 11–12 | pages = 442–5 | date = November–December 2014 | pmid = 25553160 | doi = 10.5489/cuaj.2472 | pmc = 4277526 | doi-access = free }}</ref>

Finally, nifedipine can be used in the treatment of renal calculi, which are commonly referred to as [[kidney stones]]. Studies have indicated that it helps to relieve renal colic. However, alpha blockers (such as [[tamsulosin]]) have been described as being significantly better.

==Side effects==

@@ Line 74: / Line 74: @@
 ===Other===
-[[Raynaud's phenomenon]] is often treated with nifedipine. A 2005 meta-analysis showed modest benefits (33% decrease in attack severity, 2.8-5 reduction in absolute number of attacks per week); it does conclude that most included studies used low doses of nifedipine.<ref>{{cite journal | vauthors = Thompson AE, Pope JE | title = Calcium channel blockers for primary Raynaud's phenomenon: a meta-analysis | journal = Rheumatology | volume = 44 | issue = 2 | pages = 145–50 | date = February 2005 | pmid = 15546967 | doi = 10.1093/rheumatology/keh390 | doi-access = free }}</ref>
+[[Raynaud's phenomenon]] is often treated with nifedipine. A 2005 meta-analysis showed modest benefits (33% decrease in attack severity, 2.8-5 reduction in absolute number of attacks per week); it does conclude that most included studies used low doses of nifedipine.
-[[Topical]] nifedipine has been shown to be as effective as topical nitrates for [[anal fissure]]s.<ref name="pmid12794583">{{cite journal | vauthors = Ezri T, Susmallian S | title = Topical nifedipine vs. topical glyceryl trinitrate for treatment of chronic anal fissure | journal = Diseases of the Colon and Rectum | volume = 46 | issue = 6 | pages = 805–8 | date = June 2003 | pmid = 12794583 | doi = 10.1007/s10350-004-6660-8 | s2cid = 24717470 }}</ref>
+[[Topical]] nifedipine has been shown to be as effective as topical nitrates for [[anal fissure]]s.
-Nifedipine is also used in high-altitude medicine to treat [[high altitude pulmonary edema]].<ref name="eMedicine">{{cite web| url= http://www.emedicine.com/med/topic1956.htm| title= Pulmonary Edema, High-Altitude| author1= Ali, Mir Omar| author2= Qazi, Samia| name-list-style= amp| date= 19 September 2007| publisher= eMedicine| access-date= 25 November 2007| url-status= live| archive-url= https://web.archive.org/web/20071116141543/http://www.emedicine.com/med/topic1956.htm| archive-date= 16 November 2007}}</ref>
+Nifedipine is also used in high-altitude medicine to treat [[high altitude pulmonary edema]].
-Nifedipine is one of the main choices for the treatment of [[Prinzmetal angina]] due to its vasodilating effects on the coronary arteries.<ref name=AHFS2015/>
+Nifedipine is one of the main choices for the treatment of [[Prinzmetal angina]] due to its vasodilating effects on the coronary arteries.
-Other uses include painful spasms of the [[esophagus]] such as from [[cancer]] or [[tetanus]].{{medcn|date=January 2020}} It is also used for the small subset of people with [[pulmonary hypertension]].{{medcn|date=January 2020}}
+Other uses include painful spasms of the [[esophagus]] such as from [[cancer]] or [[tetanus]].{{medcn|date=January 2020}} It is also used for the small subset of people with [[pulmonary hypertension]].
-Finally, nifedipine can be used in the treatment of renal calculi, which are commonly referred to as [[kidney stones]]. Studies have indicated that it helps to relieve renal colic. However, alpha blockers (such as [[tamsulosin]]) have been described as being significantly better.<ref>{{cite journal | vauthors = Bos D, Kapoor A | title = Update on medical expulsive therapy for distal ureteral stones: Beyond alpha-blockers | journal = Canadian Urological Association Journal | volume = 8 | issue = 11–12 | pages = 442–5 | date = November–December 2014 | pmid = 25553160 | doi = 10.5489/cuaj.2472 | pmc = 4277526 | doi-access = free }}</ref>
+Finally, nifedipine can be used in the treatment of renal calculi, which are commonly referred to as [[kidney stones]]. Studies have indicated that it helps to relieve renal colic. However, alpha blockers (such as [[tamsulosin]]) have been described as being significantly better.
 ==Side effects==