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Levomefolic acid/ja: Difference between revisions

Levomefolic acid/ja
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Created page with "<small>L</small>-メチル葉酸は水溶性で、主に腎臓から排泄される。冠動脈疾患を持つ21人の被験者を対象とした研究では、経口または非経口投与後1～3時間で血漿中濃度のピークに達した。ピーク濃度は葉酸の7倍以上高いことがわかった（129 ng/ml対14.1 ng/ml）。"
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{{Anchor|Metabolism}}
{{Anchor|Metabolism}}


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[[File:MTHFR metabolism.svg|center|thumb|650px|MTHFR代謝：葉酸サイクル、メチオニンサイクル、トランス-硫酸化、[[hyperhomocysteinemia/ja|高ホモシステイン血症]]。[[5-MTHF/ja|5-MTHF]]： 5-メチルテトラヒドロ葉酸；5,10-メチルテトラヒドロ葉酸；[[Bcl-2-associated X protein/ja|BAX]]： Bcl-2関連Xタンパク質; [[BHMT/ja|BHMT]]: ベタイン-ホモシステインS-メチルトランスフェラーゼ; [[cystathionine beta synthase/ja|CBS]]: シスタチオニンβ合成酵素; [[cystathionine gamma-lyase/ja|CGL]]: シスタチオニンγリアーゼ; [[dihydrofolate/ja|DHF]]： ジヒドロ葉酸（ビタミンB9）；[[dimethylglycine/ja|DMG]]：ジメチルグリシン；[[dTMP/ja|dTMP]]：チミジン一リン酸；[[dUMP/ja|dUMP]]：デオキシウリジン一リン酸；[[flavin adenine dinucleotide/ja|FAD]]<sup>+</sup>フラビンアデニンジヌクレオチド；[[10-formyltetrahydrofolate/ja|FTHF]]： 10-ホルミルテトラヒドロ葉酸；[[methionine synthase/ja|MS]]：メチオニン合成酵素；[[MTHFR/ja|MTHFR]]：メチレンテトラヒドロ葉酸還元酵素；[[S-アデノシル-L-ホモシステイン|SAH]]： S-アデノシル-L-ホモシステイン；[[S-adenosyl-L-homocysteine/ja|SAME]]： S-アデノシル-L-メチオニン；[[tetrahydrofolate/ja|THF]]：テトラヒドロ葉酸。]]
[[File:MTHFR metabolism.svg|center|thumb|650px|MTHFR metabolism: folate cycle, methionine cycle, trans-sulfuration and [[hyperhomocysteinemia]]. [[5-MTHF]]: 5-methyltetrahydrofolate; 5,10-methyltetrahydrofolate; [[Bcl-2-associated X protein|BAX]]: Bcl-2-associated X protein; [[BHMT]]: betaine-homocysteine S-methyltransferase; [[cystathionine beta synthase|CBS]]: cystathionine beta synthase; [[cystathionine gamma-lyase|CGL]]: cystathionine gamma-lyase; [[dihydrofolate|DHF]]: dihydrofolate (vitamin B9); [[dimethylglycine|DMG]]: dimethylglycine; [[dTMP]]: thymidine monophosphate; [[dUMP]]: deoxyuridine monophosphate; [[flavin adenine dinucleotide|FAD]]<sup>+</sup> flavine adenine dicucleotide; [[10-formyltetrahydrofolate|FTHF]]: 10-formyltetrahydrofolate; [[methionine synthase|MS]]: methionine synthase; [[MTHFR]]: methylenetetrahydrofolate reductase; [[S-adenosyl-L-homocysteine|SAH]]: S-adenosyl-L-homocysteine; [[S-adenosyl-L-methionine|SAME]]: S-adenosyl-L-methionine; [[tetrahydrofolate|THF]]: tetrahydrofolate.]]
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==医療用途==
==Medical uses==
{{Anchor|Medical uses}}
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{{Vitamin/ja}}
{{Vitamin}}
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{{二次利用|date=27 February 2024}}
[[Category:Folates]]
[[Category:Folates]]
[[Category:Coenzymes]]
[[Category:Coenzymes]]
[[Category:Medical food]]
[[Category:Medical food]]
[[Category:Patent case law]]
[[Category:Patent case law]]
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