Drug class/ja: Difference between revisions

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== 作用機序 ==

== Mechanism of action ==

~~This type of categorisation is from a~~ [[Pharmacology|~~pharmacological~~]] ~~perspective and categorises them by their biological target. Drug classes that share a common molecular~~ [[mechanism of action]] ~~modulate the activity of a specific~~ [[biological target]]~~. The definition of a mechanism of action also includes the type of activity at that biological target. For receptors, these activities include~~ [[agonist]], [[receptor antagonist|~~antagonist~~]], [[inverse agonist]]~~, or~~ [[selective receptor modulator|~~modulator~~]]~~. Enzyme target mechanisms include~~ [[enzyme activator|~~activator~~]] or [[enzyme inhibitor|~~inhibitor~~]]~~. Ion channel modulators include~~ [[channel opener|~~opener~~]] or [[channel blocker|~~blocker~~]]~~. The following are specific examples of drug classes whose definition is based on a specific mechanism of action:~~

このタイプの分類は[[Pharmacology/ja|薬理学]]の観点からのもので、生物学的標的によって分類される。共通の分子[[mechanism of action/ja|作用機序]]を持つ薬物は、特定の[[biological target/ja|生物学的標的]]の活性を調節する。作用機序の定義には、その生物学的標的における活性の種類も含まれる。受容体の場合、これらの活性には[[agonist/ja|作動薬]]、[[receptor antagonist/ja|拮抗薬]]、[[inverse agonist/ja|逆作動薬]]、または[[selective receptor modulator/ja|モジュレーター]]が含まれる。酵素標的機構には、[[enzyme activator/ja|活性化剤]]または[[enzyme inhibitor/ja|阻害剤]]が含まれる。イオンチャネル調節薬には、[[channel opener/ja|開口薬]]または[[channel blocker/ja|遮断薬]]が含まれる。以下は、特定の作用機序に基づいて定義されている薬物クラスの具体例である：

* [[5-alpha-reductase inhibitor|5-~~Alpha~~-~~reductase inhibitor~~]]

* [[5-alpha-reductase inhibitor/ja|5-α-還元酵素阻害薬]]

* [[Angiotensin II receptor antagonist]]

* [[Angiotensin II receptor antagonist/ja|アンジオテンシンII受容体拮抗薬]]

* [[ACE inhibitor]]

* [[ACE inhibitor/ja|ACE阻害薬]]

* [[Alpha-adrenergic agonist]]

* [[Alpha-adrenergic agonist/ja|α-アドレナリン作動薬]]

* [[Beta blocker]]

* [[Beta blocker/ja|β遮断薬]]

* [[Cholinergic]]

* [[Cholinergic/ja|コリン作用薬]]

* [[Dopaminergic]]

* [[Dopaminergic/ja|ドパミン作動薬]]

* [[GABAergic]]

* [[GABAergic/ja|GABA作動薬]]

* [[Glucagon-like peptide-1 agonist|~~Incretin mimetic~~]]

* [[Glucagon-like peptide-1 agonist/ja|インクレチン模倣薬]]

* [[Nonsteroidal anti-inflammatory drug]] − [[cyclooxygenase]] ~~inhibitor~~

* [[Nonsteroidal anti-inflammatory drug/ja|非ステロイド性抗炎症薬]] − [[cyclooxygenase/ja|シクロオキシゲナーゼ]]阻害薬

* [[Proton-pump inhibitor]]

* [[Proton-pump inhibitor/ja|プロトンポンプ阻害薬]]

* [[Renin inhibitor]]

* [[Renin inhibitor/ja|レニン阻害薬]]

* [[Selective glucocorticoid receptor modulator]]

* [[Selective glucocorticoid receptor modulator/ja|選択的グルココルチコイド受容体モジュレーター]]

* [[Serotonergic]]

* [[Serotonergic/ja|セロトニン作動薬]]

* [[Statin]] – [[HMG-CoA reductase]] ~~inhibitor~~

* [[Statin/ja|スタチン]] – [[HMG-CoA reductase/ja|HMG-CoA還元酵素]]阻害薬

~~</div>~~

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+== 作用機序 ==
-== Mechanism of action ==
+{{Anchor|Mechanism of action}}
-This type of categorisation is from a [[Pharmacology|pharmacological]] perspective and categorises them by their biological target. Drug classes that share a common molecular [[mechanism of action]] modulate the activity of a specific [[biological target]]. The definition of a mechanism of action also includes the type of activity at that biological target.  For receptors, these activities include [[agonist]], [[receptor antagonist|antagonist]], [[inverse agonist]], or [[selective receptor modulator|modulator]].  Enzyme target mechanisms include [[enzyme activator|activator]] or [[enzyme inhibitor|inhibitor]]. Ion channel modulators include [[channel opener|opener]] or [[channel blocker|blocker]].  The following are specific examples of drug classes whose definition is based on a specific mechanism of action:
+このタイプの分類は[[Pharmacology/ja|薬理学]]の観点からのもので、生物学的標的によって分類される。共通の分子[[mechanism of action/ja|作用機序]]を持つ薬物は、特定の[[biological target/ja|生物学的標的]]の活性を調節する。作用機序の定義には、その生物学的標的における活性の種類も含まれる。 受容体の場合、これらの活性には[[agonist/ja|作動薬]]、[[receptor antagonist/ja|拮抗薬]]、[[inverse agonist/ja|逆作動薬]]、または[[selective receptor modulator/ja|モジュレーター]]が含まれる。 酵素標的機構には、[[enzyme activator/ja|活性化剤]]または[[enzyme inhibitor/ja|阻害剤]]が含まれる。イオンチャネル調節薬には、[[channel opener/ja|開口薬]]または[[channel blocker/ja|遮断薬]]が含まれる。 以下は、特定の作用機序に基づいて定義されている薬物クラスの具体例である：
 {{div col|colwidth=33em}}
-* [[5-alpha-reductase inhibitor|5-Alpha-reductase inhibitor]]
+* [[5-alpha-reductase inhibitor/ja|5-α-還元酵素阻害薬]]
-* [[Angiotensin II receptor antagonist]]
+* [[Angiotensin II receptor antagonist/ja|アンジオテンシンII受容体拮抗薬]]
-* [[ACE inhibitor]]
+* [[ACE inhibitor/ja|ACE阻害薬]]
-* [[Alpha-adrenergic agonist]]
+* [[Alpha-adrenergic agonist/ja|α-アドレナリン作動薬]]
-* [[Beta blocker]]
+* [[Beta blocker/ja|β遮断薬]]
-* [[Cholinergic]]
+* [[Cholinergic/ja|コリン作用薬]]
-* [[Dopaminergic]]
+* [[Dopaminergic/ja|ドパミン作動薬]]
-* [[GABAergic]]
+* [[GABAergic/ja|GABA作動薬]]
-* [[Glucagon-like peptide-1 agonist|Incretin mimetic]]
+* [[Glucagon-like peptide-1 agonist/ja|インクレチン模倣薬]]
-* [[Nonsteroidal anti-inflammatory drug]] − [[cyclooxygenase]] inhibitor
+* [[Nonsteroidal anti-inflammatory drug/ja|非ステロイド性抗炎症薬]] − [[cyclooxygenase/ja|シクロオキシゲナーゼ]]阻害薬
-* [[Proton-pump inhibitor]]
+* [[Proton-pump inhibitor/ja|プロトンポンプ阻害薬]]
-* [[Renin inhibitor]]
+* [[Renin inhibitor/ja|レニン阻害薬]]
-* [[Selective glucocorticoid receptor modulator]]
+* [[Selective glucocorticoid receptor modulator/ja|選択的グルココルチコイド受容体モジュレーター]]
-* [[Serotonergic]]
+* [[Serotonergic/ja|セロトニン作動薬]]
-* [[Statin]] –  [[HMG-CoA reductase]] inhibitor
+* [[Statin/ja|スタチン]] –  [[HMG-CoA reductase/ja|HMG-CoA還元酵素]]阻害薬
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-</div>
 <div lang="en" dir="ltr" class="mw-content-ltr">