Docosahexaenoic acid: Difference between revisions

Created page with "{{About|the omega-3 fatty acid|the vitamin C metabolite also abbreviated as DHA|Dehydroascorbic acid}} {{chembox | verifiedrevid = 477163061 | Name = Docosahexaenoic acid | ImageFile = DHA_numbers.svg | ImageSize = 300px | ImageFileL2 = Docosahexaenoic-acid-3D-balls.png | ImageSizeL2 = 170px | ImageFileR2 = Docosahexaenoic-acid-3D-sf.png | ImageSizeR2 = 170px | OtherNames = cervonic acid<br />DHA<br />doconexent (INN) | PIN = (4'..."
 
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Structurally, DHA is a [[carboxylic acid]] (-''oic acid'') with a 22-[[carbon chain]] (''docosa-'' derives from the [[Ancient Greek]] for 22)  and six (''hexa-'') ''[[Cis-trans isomerism|cis]]'' [[double bond]]s (''-en-''); Its [[trivial name]] is ''cervonic acid'' (from the [[Latin]] word ''cerebrum'' for "brain"), its [[systematic name]] is ''all-cis-docosa-4,7,10,13,16,19-hexa-enoic acid''.
Structurally, DHA is a [[carboxylic acid]] (-''oic acid'') with a 22-[[carbon chain]] (''docosa-'' derives from the [[Ancient Greek]] for 22)  and six (''hexa-'') ''[[Cis-trans isomerism|cis]]'' [[double bond]]s (''-en-''); Its [[trivial name]] is ''cervonic acid'' (from the [[Latin]] word ''cerebrum'' for "brain"), its [[systematic name]] is ''all-cis-docosa-4,7,10,13,16,19-hexa-enoic acid''.


In organisms that do not eat [[algae]] containing DHA nor animal products containing DHA, DHA is instead produced internally from [[α-Linolenic acid|α-linolenic acid]], a shorter omega-3 fatty acid manufactured by plants (and also occurring in animal products as obtained from plants).<ref name=Burdge/> Limited amounts of [[Eicosapentaenoic acid|eicosapentaenoic]] and [[docosapentaenoic acid]]s are possible products of α-linolenic acid metabolism in young women and men. DHA in [[breast milk]] is important for the developing infant. Rates of DHA production in women are 15% higher than in men.
In organisms that do not eat [[algae]] containing DHA nor animal products containing DHA, DHA is instead produced internally from [[α-Linolenic acid|α-linolenic acid]], a shorter omega-3 fatty acid manufactured by plants (and also occurring in animal products as obtained from plants). Limited amounts of [[Eicosapentaenoic acid|eicosapentaenoic]] and [[docosapentaenoic acid]]s are possible products of α-linolenic acid metabolism in young women and men. DHA in [[breast milk]] is important for the developing infant. Rates of DHA production in women are 15% higher than in men.


DHA is a major fatty acid in brain [[phospholipid]]s and the [[retina]]. Preliminary research has investigated its potential benefit in [[Alzheimer's disease]], and [[cardiovascular disease]], and other disorders.
DHA is a major fatty acid in brain [[phospholipid]]s and the [[retina]]. Preliminary research has investigated its potential benefit in [[Alzheimer's disease]], and [[cardiovascular disease]], and other disorders.