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Message definition (Omega-3 fatty acid ) Both omega−6 and omega−3 fatty acids are essential: humans must consume them in their diet. Omega−6 and omega−3 eighteen-carbon polyunsaturated fatty acids compete for the same metabolic enzymes, thus the omega−6:omega−3 ratio of ingested fatty acids has significant influence on the ratio and rate of production of eicosanoids, a group of hormones intimately involved in the body's inflammatory and homeostatic processes, which include the [[prostaglandin]]s, [[leukotriene]]s, and [[thromboxane]]s, among others. Altering this ratio can change the body's metabolic and inflammatory state.
オメガ6脂肪酸もオメガ3脂肪酸も必須脂肪酸であり、ヒトは食事から摂取しなければならない。オメガ6脂肪酸とオメガ3脂肪酸の炭素数18の多価不飽和脂肪酸は、同じ代謝酵素を取り合うため、摂取する脂肪酸のオメガ6：オメガ3の比率は、特にプロスタグランジン 、ロイコトリエン 、トロンボキサン などを含む、身体の炎症と恒常性維持過程に深く関与するホルモン群であるエイコサノイドの比率と産生速度に大きな影響を及ぼす。この比率を変えることで、身体の代謝状態や炎症状態を変化させることができる。