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Message definition (Calcipotriol ) ===Pharmacokinetics=== After application and systemic uptake, calcipotriol undergoes rapid [[hepatic]] metabolism. Calcipotriol is metabolized to MC1046 (the α,β−unsaturated ketone analog), which is subsequently metabolized to its primary metabolite, the saturated ketone analog MC1080. MC1080 is then slowly metabolized to [[calcitroic acid]].
薬物動態
適用および全身への取り込み後、カルシポトリオールは急速な肝 代謝を受ける。カルシポトリオールはMC1046(α,β-不飽和ケトン類似体)に代謝され、続いてその一次代謝物である飽和ケトン類似体MC1080に代謝される。MC1080はその後ゆっくりと代謝されてカルシトロイン酸 となる。