Translations:Hydroxocobalamin/13/ja: Difference between revisions

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Created page with "===ヒドロキソコバラミン注射剤=== ヒドロキソコバラミン注射剤は、ビタミンB<sub>12</sub>欠乏の以下の原因を改善するために使用される（リストはU.S.Food and Drug Administration発行の薬物処方ラベルから引用）。 * 厳格な菜食主義者やその母乳で育てられた乳児に起こるビタミンB<sub>12</sub>の食事性欠乏（単独..."
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Revision as of 10:47, 7 April 2024

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Message definition (Hydroxocobalamin)
===Injectable hydroxocobalamin===
Injection of hydroxocobalamin is used to rectify the following causes of vitamin B<sub>12</sub> deficiency (list taken from the drug prescription label published by the [[Food and Drug Administration (United States)|U.S. Food and Drug Administration]])
* Dietary deficiency of vitamin B<sub>12</sub> occurring in strict vegetarians and in their [[breastfed]] infants (isolated vitamin B<sub>12</sub> deficiency is very rare)
* Malabsorption of vitamin B<sub>12</sub> resulting from damage to the stomach, where [[intrinsic factor]] is secreted, or damage to the [[ileum]], where intrinsic factor facilitates vitamin B<sub>12</sub> absorption. These conditions include [[tropical sprue]] and [[nontropical sprue]] (celiac disease).
* Inadequate secretion of intrinsic factor, resulting from lesions that destroy the [[gastric mucosa]] (which can be caused by ingestion of corrosives, extensive [[tumors]], and conditions associated with gastric atrophy, such as [[multiple sclerosis]], certain [[endocrine disorders]], [[Iron deficiency (medicine)|iron deficiency]], and subtotal [[gastrectomy]])
* Structural lesions leading to vitamin B<sub>12</sub> deficiency, including regional [[ileitis]], ileal reactions, and malignancies
* Competition for vitamin B<sub>12</sub> by [[intestinal parasites]] or bacteria. The [[tapeworm]] from undercooked fish (''[[Diphyllobothrium latum]]'') absorbs huge quantities of vitamin B<sub>12</sub>, and infested patients often have associated gastric atrophy. The [[blind loop syndrome]] may produce deficiency of vitamin B<sub>12</sub> or [[folate]].
* Inadequate use of vitamin B<sub>12</sub>, which may occur if [[antimetabolites]] for the vitamin are employed in the treatment of [[neoplasia]]
[[Pernicious anemia]] is the most common cause of vitamin B<sub>12</sub> deficiency. While it technically refers to anemia caused specifically by autoimmune deficiency of intrinsic factor, it is commonly used to refer to B<sub>12</sub>-deficient anemia as a whole, regardless of cause.

ヒドロキソコバラミン注射剤

ヒドロキソコバラミン注射剤は、ビタミンB12欠乏の以下の原因を改善するために使用される（リストはU.S.Food and Drug Administration発行の薬物処方ラベルから引用）。

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