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Message definition (Citric acid cycle ) In many tissues, especially heart and skeletal [[muscle tissue]], [[fatty acid]]s are broken down through a process known as [[beta oxidation]], which results in the production of mitochondrial ''acetyl-CoA'', which can be used in the citric acid cycle. [[Beta oxidation]] of [[fatty acid]]s with an odd number of [[methylene bridge]]s produces [[propionyl-CoA]], which is then converted into ''[[succinyl-CoA]]'' and fed into the citric acid cycle as an anaplerotic intermediate.
多くの組織、特に心臓や骨格筋組織 において、脂肪酸 はβ酸化 として知られる過程を経て分解され、その結果クエン酸サイクルで使用できるミトコンドリアのアセチル-CoA が産生される。奇数のメチレン橋 を持つ脂肪酸 のβ酸化 はプロピオニル-CoA を生成し、これはスクシニル-CoA に変換され、アナプレロティック中間体としてクエン酸サイクルに供給される。