Translations:Cytochrome P450/8/ja: Difference between revisions

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Created page with "シトクロムP450が触媒する最も一般的な反応はモノオキシゲナーゼ反応であり、例えば、有機基質(RH)の脂肪族位に酸素の1原子を挿入し、もう1つの酸素原子は還元されて水になる: {{center|1= RH + O<sub>2</sub> + NADPH + H<sup>+</sup> → ROH + H<sub>2</sub>O + NADP<sup>+</sup> }} 多くの水酸化反応(水酸基の挿入)にはCYP酵素が使われ..."
 
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Latest revision as of 08:23, 16 March 2024

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Message definition (Cytochrome P450)
The most common reaction catalyzed by cytochromes P450 is a monooxygenase reaction, e.g., insertion of one atom of oxygen into the aliphatic position of an organic substrate (RH), while the other oxygen atom is [[redox|reduced]] to water:
{{center|1=
RH + O<sub>2</sub> + NADPH + H<sup>+</sup> → ROH + H<sub>2</sub>O + NADP<sup>+</sup>
}} Many [[hydroxylation]] reactions (insertion of [[hydroxyl]] groups) use CYP enzymes.

シトクロムP450が触媒する最も一般的な反応はモノオキシゲナーゼ反応であり、例えば、有機基質(RH)の脂肪族位に酸素の1原子を挿入し、もう1つの酸素原子は還元されて水になる:

RH + O2 + NADPH + H+ → ROH + H2O + NADP+

多くの水酸化反応(水酸基の挿入)にはCYP酵素が使われる。