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Message definition (Dipeptidyl peptidase-4 inhibitor ) [[Glucagon]] increases [[blood glucose]] levels, and DPP-4 inhibitors reduce glucagon and blood glucose levels. The mechanism of DPP-4 inhibitors is to increase [[incretin]] levels ([[GLP-1]] and [[gastric inhibitory polypeptide|GIP]]), which inhibit [[glucagon]] release, which in turn increases [[insulin]] secretion, decreases gastric emptying, and decreases [[blood glucose]] levels.
グルカゴン は血糖値 を上昇させ、DPP-4阻害薬はグルカゴンと血糖値を低下させる。DPP-4阻害薬の機序は、インクレチン レベル（GLP-1 とGIP ）を増加させ、グルカゴン 放出を阻害し、その結果、インスリン 分泌を増加させ、胃排出を減少させ、血糖値 を低下させる。