Translations:Insulin resistance/21/ja: Difference between revisions

Latest revision as of 21:36, 10 March 2024

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Message definition (Insulin resistance)

==Pathophysiology==
In normal metabolism, the elevated blood glucose instructs beta (β) cells in the [[Islets of Langerhans]], located in the [[pancreas]], to release insulin into the blood. The insulin makes insulin-sensitive tissues in the body (primarily skeletal [[muscle]] cells, [[adipose]] tissue, and [[liver]]) absorb [[glucose]] which provides energy as well as lowers blood glucose. The beta cells reduce insulin output as the blood glucose level falls, allowing blood glucose to settle at a constant of approximately 5 mmol/L (90 mg/dL). In an ''insulin-resistant'' person, normal levels of insulin do not have the same effect in controlling blood glucose levels.

病態生理学

正常な代謝では、上昇した血中グルコースは、膵臓にあるランゲルハンス島のβ細胞にインスリンを血液中に放出するように指示する。インスリンは体内のインスリン感受性組織（主に骨格筋肉細胞、脂肪組織、肝臓）にグルコースを吸収させ、エネルギーを供給すると同時に血糖値を下げる。β細胞は血糖値が下がるとインスリンの分泌を減らし、血糖値を約5 mmol/L（90 mg/dL）に一定に保つ。インスリン抵抗性」では、正常レベルのインスリンでは血糖値をコントロールする効果はない。

Translations:Insulin resistance/21/ja: Difference between revisions

Latest revision as of 21:36, 10 March 2024

病態生理学

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