Endocrine disease: Difference between revisions
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{{Infobox medical condition (new) | {{Infobox medical condition (new) | ||
| name = Endocrine diseases | | name = Endocrine diseases | ||
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| caption = Major [[endocrine gland]]s. ([[Male]] left, [[female]] on the right.) '''1.''' [[Pineal gland]] '''2.''' [[Pituitary gland]] '''3.''' [[Thyroid gland]] '''4.''' [[Thymus]] '''5.''' [[Adrenal gland]] '''6.''' [[Pancreas]] '''7.''' [[Ovary]] '''8.''' [[Testes]] | | caption = Major [[endocrine gland]]s. ([[Male]] left, [[female]] on the right.) '''1.''' [[Pineal gland]] '''2.''' [[Pituitary gland]] '''3.''' [[Thyroid gland]] '''4.''' [[Thymus]] '''5.''' [[Adrenal gland]] '''6.''' [[Pancreas]] '''7.''' [[Ovary]] '''8.''' [[Testes]] | ||
| field = [[Endocrinology]] | | field = [[Endocrinology]] | ||
| | | QID = Q16861 | ||
| pronounce = | | pronounce = | ||
| synonyms = Endocrinopathy | | synonyms = Endocrinopathy | ||
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}} | }} | ||
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'''Endocrine diseases''' are disorders of the [[endocrine system]]. The branch of [[medicine]] associated with endocrine disorders is known as [[endocrinology]]. | '''Endocrine diseases''' are disorders of the [[endocrine system]]. The branch of [[medicine]] associated with endocrine disorders is known as [[endocrinology]]. | ||
==Types of disease== | ==Types of disease== <!--T:3--> | ||
Broadly speaking, endocrine disorders may be subdivided into three groups: | Broadly speaking, endocrine disorders may be subdivided into three groups: | ||
# Endocrine gland hypofunction/hypo[[secretion]] (leading to hormone deficiency) | # Endocrine gland hypofunction/hypo[[secretion]] (leading to hormone deficiency) | ||
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# Tumours (benign or malignant) of endocrine glands | # Tumours (benign or malignant) of endocrine glands | ||
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Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of [[hyperthyroidism]] are associated with an excess of [[thyroid hormone]] and a low level of [[thyroid stimulating hormone]]. | Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of [[hyperthyroidism]] are associated with an excess of [[thyroid hormone]] and a low level of [[thyroid stimulating hormone]]. | ||
==List of diseases== | ==List of diseases== <!--T:5--> | ||
=== Glucose homeostasis disorders === | === Glucose homeostasis disorders === <!--T:6--> | ||
* [[Diabetes]] | * [[Diabetes]] | ||
** [[Diabetes mellitus type 1|Type 1 Diabetes]] | ** [[Diabetes mellitus type 1|Type 1 Diabetes]] | ||
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* [[Glucagonoma]] | * [[Glucagonoma]] | ||
=== Thyroid disorders === | === Thyroid disorders === <!--T:7--> | ||
* [[Goitre]] | * [[Goitre]] | ||
* [[Hyperthyroidism]] | * [[Hyperthyroidism]] | ||
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* [[Thyroid hormone resistance]] | * [[Thyroid hormone resistance]] | ||
=== Calcium homeostasis disorders and Metabolic bone disease === | === Calcium homeostasis disorders and Metabolic bone disease === <!--T:8--> | ||
* [[Parathyroid gland]] disorders | * [[Parathyroid gland]] disorders | ||
** [[Hyperparathyroidism]] | ** [[Hyperparathyroidism]] | ||
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* [[Osteomalacia]] | * [[Osteomalacia]] | ||
===Pituitary gland disorders=== | ===Pituitary gland disorders=== <!--T:9--> | ||
====Posterior pituitary==== | ====Posterior pituitary==== <!--T:10--> | ||
* [[Diabetes insipidus]] | * [[Diabetes insipidus]] | ||
* Syndrome of Inappropriate Antidiuretic Hormone (SIADH) | * Syndrome of Inappropriate Antidiuretic Hormone (SIADH) | ||
====Anterior pituitary==== | ====Anterior pituitary==== <!--T:11--> | ||
* [[Hypopituitarism]] (or [[hypopituitarism|Panhypopituitarism]]) | * [[Hypopituitarism]] (or [[hypopituitarism|Panhypopituitarism]]) | ||
* [[Pituitary tumor]]s | * [[Pituitary tumor]]s | ||
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** [[Cushing's disease]] | ** [[Cushing's disease]] | ||
=== Adrenal gland disorders === | === Adrenal gland disorders === <!--T:12--> | ||
* [[Addison's disease]] | * [[Addison's disease]] | ||
* [[Adrenal crisis]] | * [[Adrenal crisis]] | ||
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* [[Hyperaldosteronism]] | * [[Hyperaldosteronism]] | ||
=== Sex hormone disorders === | === Sex hormone disorders === <!--T:13--> | ||
* [[Disorders of sex development]] or intersex disorders | * [[Disorders of sex development]] or intersex disorders | ||
** [[Hermaphroditism]] | ** [[Hermaphroditism]] | ||
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** [[Polycystic ovary syndrome|Polycystic ovary syndrome (PCOS)]] | ** [[Polycystic ovary syndrome|Polycystic ovary syndrome (PCOS)]] | ||
=== Tumours of the endocrine glands not mentioned elsewhere === | === Tumours of the endocrine glands not mentioned elsewhere === <!--T:14--> | ||
[[File:Multiple endocrine neoplasia.png|thumb|[[Multiple endocrine neoplasia]] types.]] | [[File:Multiple endocrine neoplasia.png|thumb|[[Multiple endocrine neoplasia]] types.]] | ||
* [[Multiple endocrine neoplasia]] | * [[Multiple endocrine neoplasia]] | ||
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* [[Carcinoid syndrome]] | * [[Carcinoid syndrome]] | ||
=== See also separate organs === | === See also separate organs === <!--T:15--> | ||
* [[Autoimmune polyendocrine syndrome]]s | * [[Autoimmune polyendocrine syndrome]]s | ||
* [[Incidentaloma]] - an unexpected finding on diagnostic imaging, often of endocrine glands | * [[Incidentaloma]] - an unexpected finding on diagnostic imaging, often of endocrine glands | ||
==Endocrine emergencies== | ==Endocrine emergencies== <!--T:16--> | ||
In endocrinology, medical emergencies include [[diabetic ketoacidosis]], [[hyperosmolar hyperglycemic state]], [[hypoglycemia|hypoglycemic coma]], [[adrenal insufficiency|acute adrenocortical insufficiency]], [[phaeochromocytoma]] crisis, [[hypercalcemic crisis]], [[thyroid storm]], [[myxoedema coma]] and [[pituitary apoplexy]]. | In endocrinology, medical emergencies include [[diabetic ketoacidosis]], [[hyperosmolar hyperglycemic state]], [[hypoglycemia|hypoglycemic coma]], [[adrenal insufficiency|acute adrenocortical insufficiency]], [[phaeochromocytoma]] crisis, [[hypercalcemic crisis]], [[thyroid storm]], [[myxoedema coma]] and [[pituitary apoplexy]]. | ||
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Emergencies arising from decompensated [[pheochromocytoma]]s or [[parathyroid]] adenomas are sometimes referred for emergency resection when aggressive medical therapies fail to control the patient's state, however the surgical risks are significant, especially blood pressure lability and the possibility of cardiovascular collapse after resection (due to a brutal drop in respectively catecholamines and calcium, which must be compensated with gradual normalization). It remains debated when emergency surgery is appropriate as opposed to urgent or elective surgery after continued attempts to stabilize the patient, notably in view of newer and more efficient medications and protocols. | Emergencies arising from decompensated [[pheochromocytoma]]s or [[parathyroid]] adenomas are sometimes referred for emergency resection when aggressive medical therapies fail to control the patient's state, however the surgical risks are significant, especially blood pressure lability and the possibility of cardiovascular collapse after resection (due to a brutal drop in respectively catecholamines and calcium, which must be compensated with gradual normalization). It remains debated when emergency surgery is appropriate as opposed to urgent or elective surgery after continued attempts to stabilize the patient, notably in view of newer and more efficient medications and protocols. | ||
==See also== | ==See also== <!--T:18--> | ||
* [[List of MeSH codes (C19)]] | * [[List of MeSH codes (C19)]] | ||
* [[List of ICD-9 codes 240-279: Endocrine, nutritional and metabolic diseases, and immunity disorders]] | * [[List of ICD-9 codes 240-279: Endocrine, nutritional and metabolic diseases, and immunity disorders]] | ||
==References== | ==References== <!--T:19--> | ||
{{Reflist}} | {{Reflist}} | ||
== External links == | == External links == <!--T:20--> | ||
{{Medical resources | {{Medical resources | ||
| DiseasesDB = | | DiseasesDB = | ||
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{{Disease groups}} | {{Disease groups}} | ||
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{{二次利用|date=17 October 2023}} | {{二次利用|date=17 October 2023}} | ||
{{DEFAULTSORT:Endocrine Disease}} | {{DEFAULTSORT:Endocrine Disease}} |