class of chemical compounds
1 statement, 0 sitelinks - 11:46, 4 December 2023
...n what compound is in the ring position, in the C-4 region of the proximal phenyl ring, and how the thiazole ring relates.
...is bonded to the distal ring (given that in the C-4 region of the proximal phenyl ring is a Cl atom).
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17 KB (2,477 words) - 09:56, 14 February 2024
...n what compound is in the ring position, in the C-4 region of the proximal phenyl ring, and how the thiazole ring relates.
...is bonded to the distal ring (given that in the C-4 region of the proximal phenyl ring is a Cl atom).
...
17 KB (2,553 words) - 09:56, 14 February 2024
{{Short description|Class of organic compounds used in medicine and agriculture}}
'''Sulfonylureas''' or '''sulphonylureas''' are a class of [[organic compounds]] used in [[medicine]] and [[agriculture]]. The functional group consists o
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12 KB (1,572 words) - 20:36, 12 March 2024
{{Short description|Class of organic compounds used in medicine and agriculture}}
'''Sulfonylureas''' or '''sulphonylureas''' are a class of [[organic compounds]] used in [[medicine]] and [[agriculture]]. The functional group consists o
...
12 KB (1,638 words) - 20:35, 12 March 2024
...olidine]], cyanopyrrolidine, [[thiazolidine]] and cyanothiazolidine. These compounds commonly form covalent bonds to the [[catalytic]] residue Ser630.
...two cyanopyrrolidine DPP-4 inhibitors, which they published in 1995. These compounds had excellent [[potency (pharmacology)|potency]] and improved chemical stab
...
32 KB (4,417 words) - 10:31, 12 March 2024
...olidine]], cyanopyrrolidine, [[thiazolidine]] and cyanothiazolidine. These compounds commonly form covalent bonds to the [[catalytic]] residue Ser630.
...two cyanopyrrolidine DPP-4 inhibitors, which they published in 1995. These compounds had excellent [[potency (pharmacology)|potency]] and improved chemical stab
...
33 KB (4,561 words) - 10:30, 12 March 2024
2-カルボキシ-ベンズアミド-基を2-カルボキシ-[[phenyl/ja|フェニル]]-基に置き換えると、[[lipophilic/ja|親油性]]の[[biphenyl/ja|ビフェニル]]-含有EXP-7711がで
...ylic acid/ja|カルボン酸]][[metabolite/ja|代謝物]] EXP 3174となる。EXP3174は、親[[chemical compounds/ja|化合物]]よりも強力なAT<sub>1</sub>受容体拮抗薬であり、他のいくつかのARBを開発し続けるモデルとなっている。
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27 KB (998 words) - 12:39, 28 March 2024
...)|derivatives]] diminished blood pressure responses to Ang II in rats. Two compounds, [[S-8307]] and [[S-8308]], were later found to be highly specific and prom
...were bound at the same receptor site. These two substances served as lead compounds for further optimization of AT<sub>1</sub> receptor blockers.
...
22 KB (3,221 words) - 10:25, 28 March 2024
...)|derivatives]] diminished blood pressure responses to Ang II in rats. Two compounds, [[S-8307]] and [[S-8308]], were later found to be highly specific and prom
...were bound at the same receptor site. These two substances served as lead compounds for further optimization of AT<sub>1</sub> receptor blockers.
...
22 KB (3,315 words) - 10:25, 28 March 2024