central term in chemical kinetics
1 statement, 0 sitelinks - 16:31, 18 February 2023
'''酵素''' ({{IPAc-en|ˈ|ɛ|n|z|aɪ|m|z}}) は、[[chemical reactions/ja|化学反応]]を促進することによって生物学的[[catalyst/ja|触媒]]として働く[[protein/ja|タンパク質
...ことが知られている。他の生体触媒は[[Ribozyme/ja|触媒RNA分子]]で、[[ribozymes/ja|リボザイム]]と呼ばれる。酵素の[[Chemical specificity/ja|特異性]]は、そのユニークな[[tertiary structure/ja|立体構造]]に由来する。
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64 KB (2,204 words) - 15:33, 22 February 2024
...se compounds had excellent [[potency (pharmacology)|potency]] and improved chemical stability.
...ignificant [[solvent]] access that makes it possible to tune the [[physico-chemical]] properties of the inhibitors that leads to better [[pharmacokinetic]] beh
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32 KB (4,417 words) - 10:31, 12 March 2024
...}) are [[protein]]s that act as biological [[catalyst]]s by accelerating [[chemical reactions]]. The [[molecules]] upon which enzymes may act are called [[subs
...[[Ribozyme|catalytic RNA molecules]], called [[ribozymes]]. An enzyme's [[Chemical specificity|specificity]] comes from its unique [[tertiary structure|three-
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52 KB (7,533 words) - 19:19, 21 February 2024
...attempts to analyze chemical [[metabolism]] and to discover the fate of a chemical from the moment that it is administered up to the point at which it is comp
...sm|'''<u>M</u>'''etabolism]] (or biotransformation, or inactivation) – the chemical reactions of the drug and irreversible breakdown into [[metabolite]]s (e.g.
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44 KB (6,066 words) - 12:21, 15 November 2023
...se compounds had excellent [[potency (pharmacology)|potency]] and improved chemical stability.
...ignificant [[solvent]] access that makes it possible to tune the [[physico-chemical]] properties of the inhibitors that leads to better [[pharmacokinetic]] beh
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33 KB (4,561 words) - 10:30, 12 March 2024
<!-- Chemical data -->
...out 50% (42–100%). Food intake has no clinically relevant influence on the kinetics of telmisartan. [[Plasma protein binding]] is over 99.5%, mainly to [[album
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8 KB (1,021 words) - 16:03, 28 March 2024
...}) are [[protein]]s that act as biological [[catalyst]]s by accelerating [[chemical reactions]]. The [[molecules]] upon which enzymes may act are called [[subs
...[[Ribozyme|catalytic RNA molecules]], called [[ribozymes]]. An enzyme's [[Chemical specificity|specificity]] comes from its unique [[tertiary structure|three-
...
54 KB (7,773 words) - 19:18, 21 February 2024
<!-- Chemical data -->
...out 50% (42–100%). Food intake has no clinically relevant influence on the kinetics of telmisartan. [[Plasma protein binding]] is over 99.5%, mainly to [[album
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8 KB (1,075 words) - 16:02, 28 March 2024
|[[Nissan Chemical Corporation|日産化学]]
[[File:Dipines.svg|thumb|right|General chemical structure of dihydropyridine calcium channel blockers (dipines)]]
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23 KB (2,941 words) - 15:18, 11 November 2023
...素]]に[[amino/ja|アミノ基]]、[[carboxyl/ja|カルボキシル基]]、および可変の[[side chain/ja|側鎖]]が[[chemical bond/ja||結合]]している[[alpha carbon/ja|α-炭素]]を含む共通の構造的特徴を持っている。[[proline/ja|プロリ
短いタンパク質は[[peptide synthesis/ja|ペプチド合成]]と呼ばれる一連の方法によって化学的に合成することもできる。これは[[chemical ligation/ja|化学ライゲーション]]などの[[organic synthesis/ja|有機合成]]技術に依存して高収率でペプチドを生産する
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70 KB (2,326 words) - 18:42, 23 April 2024
|[[Nissan Chemical Corporation|日産化学]]
[[File:Dipines.svg|thumb|right|General chemical structure of dihydropyridine calcium channel blockers (dipines)]]
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23 KB (3,025 words) - 14:41, 11 November 2023
{{Short description|Set of chemical reactions in organisms}}
...eir environments. The word ''metabolism'' can also refer to the sum of all chemical reactions that occur in living organisms, including [[digestion]] and the t
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54 KB (7,765 words) - 19:27, 22 January 2024
{{Short description|Set of chemical reactions in organisms}}
...eir environments. The word ''metabolism'' can also refer to the sum of all chemical reactions that occur in living organisms, including [[digestion]] and the t
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55 KB (7,943 words) - 19:27, 22 January 2024
...'metabolē'', "change")とは、[[organisms/ja|生物]]における[[life/ja|生命]]を維持するための一連の[[chemical reactions/ja|化学反応]]のことである。代謝の3つの主な機能は、食物中のエネルギーを細胞プロセスを実行するために利用可能な[[energy
...ell membrane/ja|細胞膜]]のような内外の[[biological membrane/ja|生体膜]]の一部としての利用である。その[[chemical energy/ja|化学エネルギー]]を利用することもできる。脂質は、酸素を含む小さな極性領域を持つ長い非極性炭化水素鎖を含む脂肪酸のポリマーである。
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68 KB (2,680 words) - 16:54, 13 April 2024
...fied by [[post-translational modification]], which alters the physical and chemical properties, folding, stability, activity, and ultimately, the function of t
[[File:Peptide-Figure-Revised.png|thumb|upright=1.35|Chemical structure of the peptide bond (bottom) and the three-dimensional structure
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55 KB (7,841 words) - 18:41, 23 April 2024
...fied by [[post-translational modification]], which alters the physical and chemical properties, folding, stability, activity, and ultimately, the function of t
[[File:Peptide-Figure-Revised.png|thumb|upright=1.35|Chemical structure of the peptide bond (bottom) and the three-dimensional structure
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56 KB (8,015 words) - 18:40, 23 April 2024
...tory of penicillin|as with penicillin]]. More recently, [[chemical library|chemical libraries]] of synthetic [[small molecule]]s, [[natural product]]s or [[ext
...= 28 February 2014}}</ref> Another champion of the approach of developing chemical analogues of known active substances was [[Sir David Jack]] at Allen and Ha
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55 KB (7,244 words) - 08:05, 4 January 2023