study of how biological viruses cause diseases in their target hosts, usually carried out at the cellular or molecular level
1 statement, 0 sitelinks - 14:44, 29 June 2023
...s, the same [[mechanism of action]] (i.e. binding to the same [[biological target]]), a related [[mode of action]], and/or are used to treat the same disease
...[inverse agonist]], or [[selective receptor modulator|modulator]]. Enzyme target mechanisms include [[enzyme activator|activator]] or [[enzyme inhibitor|inh
...
7 KB (907 words) - 10:49, 25 March 2024
...s, the same [[mechanism of action]] (i.e. binding to the same [[biological target]]), a related [[mode of action]], and/or are used to treat the same disease
...[inverse agonist]], or [[selective receptor modulator|modulator]]. Enzyme target mechanisms include [[enzyme activator|activator]] or [[enzyme inhibitor|inh
...
7 KB (941 words) - 10:47, 25 March 2024
...同じ[[mechanism of action/ja|作用機序(mechanism of action)]]（すなわち、同じ[[biological target/ja|生物学的標的]]に結合する）を持ち、関連した[[mode of action/ja|作用機序(mode of action)]]を持ち、および/
...生物学的標的によって分類される。共通の分子[[mechanism of action/ja|作用機序]]を持つ薬物は、特定の[[biological target/ja|生物学的標的]]の活性を調節する。作用機序の定義には、その生物学的標的における活性の種類も含まれる。 受容体の場合、これらの活性には[[agon
...
9 KB (422 words) - 17:29, 25 March 2024
==Target for antifungal drugs==
...in cell membranes of fungi, yet absent in those of animals, it is a useful target for [[antifungal]] drugs. Ergosterol is also present in the cell membranes
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6 KB (896 words) - 10:36, 11 April 2024
==Target for antifungal drugs== <!--T:4-->
...in cell membranes of fungi, yet absent in those of animals, it is a useful target for [[antifungal]] drugs. Ergosterol is also present in the cell membranes
...
7 KB (930 words) - 10:35, 11 April 2024
...e]] of [[Chemistry|chemical]] [[molecule]]s and their activities against [[biological assays]]. The system is maintained by the [[National Center for Biotechnolo
...000 genes). It also contains RNA interference (RNAi) screening assays that target over 15,000 genes.<ref>{{Cite journal |last1=Kim |first1=Sunghwan |last2=Th
...
11 KB (1,477 words) - 15:23, 14 November 2023
...mall molecules may be used as research tools to probe [[function (biology)|biological function]] as well as [[lead compound|leads]] in the development of new [[p
...of the [[biological target|target]]. Small molecules can have a variety of biological functions or applications, serving as [[cell signaling]] molecules, [[drug]
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11 KB (1,440 words) - 16:29, 3 January 2023
Protein binding can influence the drug's [[biological half-life]]. The bound portion may act as a reservoir or depot from which t
...n potentially double (depending on whether the free molecules get to their target before they are eliminated by metabolism or excretion). This change in pha
...
8 KB (1,201 words) - 12:11, 15 November 2023
...s and Genomes''') is a collection of databases dealing with [[genome]]s, [[biological pathway]]s, [[disease]]s, [[drug]]s, and [[chemical substance]]s. KEGG is u
.../ref> Foreseeing the need for a computerized resource that can be used for biological interpretation of [[genome project|genome sequence data]], he started devel
...
15 KB (1,996 words) - 13:53, 14 November 2023
...iotech drugs, drug targets, drug transporters, drug target sequences, drug target SNPs, drug metabolites, drug descriptions, disease associations, dosage dat
...chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.<ref name="pmid16381955
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15 KB (1,956 words) - 12:25, 15 November 2023
== Biological and biochemical features ==
...y means of antibiotic efflux, antibiotic target alteration, and antibiotic target protection were present in all ''L. acidophilus'' strains, providing protec
...
17 KB (2,382 words) - 08:05, 17 April 2024
== Biological and biochemical features ==
...y means of antibiotic efflux, antibiotic target alteration, and antibiotic target protection were present in all ''L. acidophilus'' strains, providing protec
...
17 KB (2,418 words) - 08:05, 17 April 2024
...'' is used as a term to encompass these [[endogenous]] and [[exogenous]] [[Biological activity|bioactive]] species). More specifically, it is the study of the in
...stribution, [[metabolism]], and [[excretion]] (ADME) of chemicals from the biological systems.
...
30 KB (3,998 words) - 20:36, 8 January 2023
...xtra-renal synthesis of calcitriol from calcifediol has been shown to have biological effects in these tissues.
...[[calcitroic acid]], but 24,25-(OH)<sub>2</sub>D<sub>3</sub> may have some biological actions itself.
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10 KB (1,460 words) - 20:39, 12 April 2024
...xtra-renal synthesis of calcitriol from calcifediol has been shown to have biological effects in these tissues.
...[[calcitroic acid]], but 24,25-(OH)<sub>2</sub>D<sub>3</sub> may have some biological actions itself.
...
11 KB (1,502 words) - 20:39, 12 April 2024
{{short description|Drug made from biological source}}
...ed in, extracted from, or [[semisynthesis|semisynthesized]] from [[biology|biological]] sources. Different from [[total synthesis|totally synthesized]] pharmaceu
...
29 KB (3,642 words) - 16:31, 3 January 2023
...may have several effects on different target organs, and, conversely, one target organ may be affected by more than one hormone.
...n identified by early anatomists, a more humoral approach to understanding biological function and disease was favoured by the [[Ancient Greece|ancient Greek]] a
...
17 KB (2,368 words) - 13:43, 20 February 2024
...may have several effects on different target organs, and, conversely, one target organ may be affected by more than one hormone.
...n identified by early anatomists, a more humoral approach to understanding biological function and disease was favoured by the [[Ancient Greece|ancient Greek]] a
...
18 KB (2,440 words) - 13:43, 20 February 2024
...put screening]] of large compounds libraries against isolated [[biological target]]s which are hypothesized to be disease-modifying in a process known as [[r
...macology)|potency]], [[Metabolism|metabolic]] stability (to increase the [[Biological half-life|half-life]]), and oral [[bioavailability]]. Once a compound that
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55 KB (7,244 words) - 08:05, 4 January 2023